17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
(KUFRQPKVAWMTJO-LMZWQJSESA-N)
Structure
- SMILES
- CO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(C2=O)NC(=O)/C(=C/C=C\[C@@H]([C@H](/C(=C/[C@@H]([C@H]1O)C)/C)OC(=O)N)OC)/C
- Type(s)
- Investigational
- Molecular Formula:
- C32H48N4O8
- Molecular Weight:
- 616.746
- Log P:
- 3.3332
- Hydrogen Bond Acceptor:
- 12
- Hydrogen Bond Donor:
- 4
- TPSA:
- 169.52
- CAS Number(s):
- 150270-08-9; 467214-20-6
Synonym(s)
1.
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
2.
17-(dimethylaminoethylamino)-17-demethoxy-geldanamycin
3.
17-DMAG
4.
17-desmethoxy-17-n,n-dimethylaminoethylamino-geldanamycin
5.
17-dimethylaminoethylamino-17-demethoxy-geldanamycin
6.
17DMAG
7.
KOS 1022
8.
KOS-1022
9.
KOS1022
10.
NSC 707545
11.
NSC707545
12.
alvespimycin
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Blood Coagulation Disorders | 27224288 | CTD | |
| 2 | Endotoxemia | 27224288 | CTD | |
| 3 | Hyperalgesia | 19833175 | CTD | |
| 4 | Hypotension | 27224288 | CTD | |
| 5 | Multiple Organ Failure | 27224288 | CTD |
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