MetaADEDB 2.0 @ LMMD
adefovir
(SUPKOOSCJHTBAH-UHFFFAOYSA-N)
Structure
SMILES
Nc1ncnc2c1ncn2CCOCP(=O)(O)O
Type(s)
Investigational
Molecular Formula:
C8H12N5O4P
Molecular Weight:
273.186
Log P:
0.1415
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
3
TPSA:
146.19
CAS Number(s):
106941-25-7
Synonym(s)
1.
adefovir
2.
9-(2-phosphonomethoxyethyl)adenine
3.
9-(2-phosphonylmethoxyethyl)adenine
4.
9-PMEA
External Link(s)
MeSHC053001
PubChem Compound60172
BindingDB50001103
ChEBI134512
2469
CHEMBLCHEMBL484
DrugBankDB13868
KEGGcpd:C11277
dr:D02768
Therapeutic Target DatabaseD00UUM
ZINC21297308
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood pressure fluctuationFAERS: 1US FAERS
2Bone painFAERS: 1SIDER
US FAERS
3FatigueFAERS: 1US FAERS
4HeadacheFAERS: 1SIDER
US FAERS
5Muscle tightnessFAERS: 1US FAERS
6MyalgiaFAERS: 1SIDER
US FAERS
7SomnolenceFAERS: 1US FAERS
8Abdominal PainSIDER
9Alanine Aminotransferase IncreasedSIDER
10AnorexiaSIDER
11Ascites17409599CTD
12AstheniaSIDER
13Back PainSIDER
14Blood creatinine increasedSIDER
15Blood phosphorus decreasedSIDER
16Chest PainSIDER
17Creatinine increasedSIDER
18DermatitisSIDER
19DyspepsiaSIDER
20Fanconi SyndromeSIDER
21FlatulenceSIDER
22FractureSIDER
23Gastrointestinal PainSIDER
24GlycosuriaSIDER
25Hepatitis B e antigen positiveSIDER
26Hepatitis B, Chronic

View details

16338024
18350610
18367858
19152409
19346146
19712848
20332649
20559524
20659226
20729619
20872709
 		CTD
27Hepatitis B

View details

10377169
11709523
12500185
16152756
16448446
16913979
17052272
17404847
17409599
17687019
17854030
17935165
17983429
18795708
19203548
19373086
 		CTD
28HepatitisSIDER
29Kidney Diseases12460055CTD
30Liver Cirrhosis17409599CTD
31MalnutritionSIDER
32Musculoskeletal discomfortSIDER
33MyopathySIDER
34NauseaSIDER
35OsteomalaciaSIDER
36PancreatitisSIDER
37PharyngitisSIDER
38Phosphorus lowSIDER
39Proteinuria19203548CTD
40PruritusSIDER
41Renal tubular disorderSIDER
42SinusitisSIDER
43ThrombocytopeniaSIDER
44VomitingSIDER
45Weight decreasedSIDER
46jaundiceSIDER
47nervous system disorderSIDER
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