MetaADEDB 2.0 @ LMMD
isavuconazole
(LWXUIUUOMSMZKJ-KLFWAVJMSA-M)
Structure
SMILES
[O-]S(=O)(=O)O.CNCC(=O)OCc1cccnc1N(C(=O)OC([n+]1cnn(c1)C[C@](c1cc(F)ccc1F)([C@H](c1scc(n1)c1ccc(cc1)C#N)C)O)C)C
Molecular Formula:
C35H36F2N8O9S2
Molecular Weight:
814.835
Log P:
5.0609
Hydrogen Bond Acceptor:
17
Hydrogen Bond Donor:
3
TPSA:
273.42
CAS Number(s):
946075-13-4
Synonym(s)
1.
isavuconazole
2.
BAL 8557
3.
BAL-8557
4.
BAL8557
5.
Cresemba
6.
isavuconazonium sulfate
External Link(s)
MeSHC508735
PubChem Compound72196309
ChEBI85977
CHEMBLCHEMBL3137333
KEGGdr:D10643
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Inappropriate schedule of drug administrationFAERS: 33US FAERS
2NauseaFAERS: 23US FAERS
3Wrong technique in product usage processFAERS: 19US FAERS
4Drug ineffectiveFAERS: 15US FAERS
5Drug dose omissionFAERS: 13US FAERS
6MalaiseFAERS: 12US FAERS
7HeadacheFAERS: 11US FAERS
8InfectionFAERS: 11US FAERS
9PneumoniaFAERS: 11US FAERS
10VomitingFAERS: 11US FAERS
11Incorrect product storageFAERS: 10US FAERS
12Drug prescribing errorFAERS: 9US FAERS
13Product storage errorFAERS: 9US FAERS
14Product use in unapproved indicationFAERS: 7US FAERS
15FatigueFAERS: 6US FAERS
16TremorFAERS: 6US FAERS
17AlopeciaFAERS: 5US FAERS
18AstheniaFAERS: 5US FAERS
19Circumstance or information capable of leading to medication errorFAERS: 5US FAERS
20PainFAERS: 5US FAERS
21Peripheral swellingFAERS: 5US FAERS
22Abdominal PainFAERS: 4US FAERS
23Burning sensationFAERS: 4US FAERS
24DizzinessFAERS: 4US FAERS
25OverdoseFAERS: 4US FAERS
26Product prescribing errorFAERS: 4US FAERS
27Product use issueFAERS: 4US FAERS
28Weight decreasedFAERS: 4US FAERS
29Blood alkaline phosphatase increasedFAERS: 3US FAERS
30General physical health deteriorationFAERS: 3US FAERS
31HypotensionFAERS: 3US FAERS
32Inappropriate schedule of product administrationFAERS: 3US FAERS
33MyalgiaFAERS: 3US FAERS
34Poor quality drug administeredFAERS: 3US FAERS
35Product packaging issueFAERS: 3US FAERS
36Product physical issueFAERS: 3US FAERS
37Product size issueFAERS: 3US FAERS
38SomnolenceFAERS: 3US FAERS
39Therapy non-responderFAERS: 3US FAERS
40Urinary tract infectionFAERS: 3US FAERS
41White blood cell count decreasedFAERS: 3US FAERS
42treatment failureFAERS: 3US FAERS
43Abdominal discomfortFAERS: 2US FAERS
44ArthralgiaFAERS: 2US FAERS
45Atrial FibrillationFAERS: 2US FAERS
46Back PainFAERS: 2US FAERS
47Blood creatinine increasedFAERS: 2US FAERS
48Chest discomfortFAERS: 2US FAERS
49Clostridium difficile infectionFAERS: 2US FAERS
50ConstipationFAERS: 2US FAERS
51DehydrationFAERS: 2US FAERS
52DeliriumFAERS: 2US FAERS
53Drug administered to patient of inappropriate ageFAERS: 2US FAERS
54DysgeusiaFAERS: 2US FAERS
55Feeling abnormalFAERS: 2US FAERS
56GastrostomyFAERS: 2US FAERS
57InfluenzaFAERS: 2US FAERS
58Intercepted medication errorFAERS: 2US FAERS
59Loss of personal independence in daily activitiesFAERS: 2US FAERS
60NasopharyngitisFAERS: 2US FAERS
61PneumonitisFAERS: 2US FAERS
62Prescribed underdoseFAERS: 2US FAERS
63Product supply issueFAERS: 2US FAERS
64SepsisFAERS: 2US FAERS
65Systemic mycosisFAERS: 2US FAERS
66TinnitusFAERS: 2US FAERS
67Accidental exposure to productFAERS: 1US FAERS
68Activities of daily living impairedFAERS: 1US FAERS
69Acute respiratory failureFAERS: 1US FAERS
70AgeusiaFAERS: 1US FAERS
71Alanine Aminotransferase IncreasedFAERS: 1US FAERS
72Alternaria infectionFAERS: 1US FAERS
73Anaphylactoid ReactionFAERS: 1US FAERS
74AnosmiaFAERS: 1US FAERS
75Aortic AneurysmFAERS: 1US FAERS
76Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
77AspergillomaFAERS: 1US FAERS
78BedriddenFAERS: 1US FAERS
79Bladder NeoplasmFAERS: 1US FAERS
80Blood phosphorus increasedFAERS: 1US FAERS
81Blood potassium decreasedFAERS: 1US FAERS
82Blood potassium increasedFAERS: 1US FAERS
83Blood sodium decreasedFAERS: 1US FAERS
84Bone painFAERS: 1US FAERS
85Cardiac ArrestFAERS: 1US FAERS
86CellulitisFAERS: 1US FAERS
87Cerebrovascular accidentFAERS: 1US FAERS
88Chest PainFAERS: 1US FAERS
89ChillsFAERS: 1US FAERS
90ChokingFAERS: 1US FAERS
91ColitisFAERS: 1US FAERS
92CryingFAERS: 1US FAERS
93DisabilityFAERS: 1US FAERS
94Disease recurrenceFAERS: 1US FAERS
95Drug dispensing errorFAERS: 1US FAERS
96Drug effect delayedFAERS: 1US FAERS
97Drug effect incompleteFAERS: 1US FAERS
98Drug level below therapeuticFAERS: 1US FAERS
99Drug level decreasedFAERS: 1US FAERS
100Drug level increasedFAERS: 1US FAERS
101Drug resistanceFAERS: 1US FAERS
102EncephalitisFAERS: 1US FAERS
103EructationFAERS: 1US FAERS
104Escherichia infectionFAERS: 1US FAERS
105Exposure via inhalationFAERS: 1US FAERS
106Facial PainFAERS: 1US FAERS
107Feeding tube userFAERS: 1US FAERS
108Fluid overloadFAERS: 1US FAERS
109Fluoride increasedFAERS: 1US FAERS
110Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
111Gastrointestinal infectionFAERS: 1US FAERS
112Gastrointestinal motility disorderFAERS: 1US FAERS
113HepatotoxicityFAERS: 1US FAERS
114HypersensitivityFAERS: 1US FAERS
115HypophagiaFAERS: 1US FAERS
116Incorrect dose administeredFAERS: 1US FAERS
117Incorrect route of product administrationFAERS: 1US FAERS
118Intentional dose omissionFAERS: 1US FAERS
119Joint swellingFAERS: 1US FAERS
120LethargyFAERS: 1US FAERS
121Lower respiratory tract infectionFAERS: 1US FAERS
122Lung transplant rejectionFAERS: 1US FAERS
123MalabsorptionFAERS: 1US FAERS
124Malignant neoplasm progressionFAERS: 1US FAERS
125Maternal exposure before pregnancyFAERS: 1US FAERS
126Memory impairmentFAERS: 1US FAERS
127MenorrhagiaFAERS: 1US FAERS
128MucormycosisFAERS: 1US FAERS
129Mucosal hypertrophyFAERS: 1US FAERS
130MyopathyFAERS: 1US FAERS
131Nasal PolypsFAERS: 1US FAERS
132NeutropeniaFAERS: 1US FAERS
133No adverse eventFAERS: 1US FAERS
134NoduleFAERS: 1US FAERS
135Pelvic InfectionFAERS: 1US FAERS
136Post procedural complicationFAERS: 1US FAERS
137Post procedural dischargeFAERS: 1US FAERS
138Prescribed overdoseFAERS: 1US FAERS
139Product administered to patient of inappropriate ageFAERS: 1US FAERS
140Product blister packaging issueFAERS: 1US FAERS
141Product coating issueFAERS: 1US FAERS
142Product depositFAERS: 1US FAERS
143Product dispensing errorFAERS: 1US FAERS
144Product packaging counterfeitFAERS: 1US FAERS
145Product packaging quantity issueFAERS: 1US FAERS
146Product solubility abnormalFAERS: 1US FAERS
147Product taste abnormalFAERS: 1US FAERS
148PruritusFAERS: 1US FAERS
149Pulmonary HypertensionFAERS: 1US FAERS
150Pulmonary thrombosisFAERS: 1US FAERS
151Renal tubular necrosisFAERS: 1US FAERS
152Respiratory FailureFAERS: 1US FAERS
153Respiratory arrestFAERS: 1US FAERS
154Rheumatoid ArthritisFAERS: 1US FAERS
155Rift Valley FeverFAERS: 1US FAERS
156Sinus painFAERS: 1US FAERS
157Supraventricular tachycardiaFAERS: 1US FAERS
158SwellingFAERS: 1US FAERS
159TachycardiaFAERS: 1US FAERS
160Throat cancerFAERS: 1US FAERS
161Throat irritationFAERS: 1US FAERS
162ThrombocytopeniaFAERS: 1US FAERS
163Toxicity to various agentsFAERS: 1US FAERS
164Transaminases increasedFAERS: 1US FAERS
165Wrong technique in drug usage processFAERS: 1US FAERS
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