MetaADEDB 2.0 @ LMMD
Phenoxybenzamine
(QZVCTJOXCFMACW-UHFFFAOYSA-N)
Structure
SMILES
ClCCN(C(COc1ccccc1)C)Cc1ccccc1
Type(s)
Approved
ATC code(s)
C04AX02
Molecular Formula:
C18H22ClNO
Molecular Weight:
303.826
Log P:
4.1949
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
59-96-1
Synonym(s)
1.
Phenoxybenzamine
2.
Dibenylene
3.
Dibenyline
4.
Dibenziran
5.
Dibenzylin
6.
Dibenzyline
7.
Dibenzyran
8.
Phenoxybenzamine Hydrochloride
9.
Hydrochloride, Phenoxybenzamine
External Link(s)
MeSHD010643
PubChem Compound4768
BindingDB50017679
ChEBI8077
CHEMBLCHEMBL753
DrugBankDB00925
DrugCentral2136
IUPHAR/BPS Guide to PHARMACOLOGY7268
KEGGcpd:C07435
dr:D08358
Therapeutic Target DatabaseD0X2DK
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 2
Canada Vigilance: 7		16130025CTD
Canada Vigilance
US FAERS
2DysplasiaFAERS: 1US FAERS
3HydronephrosisFAERS: 1US FAERS
4HypotensionFAERS: 1
Canada Vigilance: 2

View details

2217678
2894880
2900909
12019395
15166586
 		CTD
Canada Vigilance
US FAERS
5Abdominal discomfortSIDER
6Alanine Aminotransferase IncreasedCanada Vigilance: 1Canada Vigilance
7Albuminuria11576345CTD
8Aspartate Aminotransferase IncreasedCanada Vigilance: 1Canada Vigilance
9AstheniaSIDER
10BlindnessCanada Vigilance: 1Canada Vigilance
11Carcinoma, Small Cell16130025CTD
12Cardiac ArrestCanada Vigilance: 1Canada Vigilance
13Causalgia6726371CTD
14DrowsinessSIDER
15Erectile dysfunction3640652CTD
16FatigueCanada Vigilance: 6Canada Vigilance
SIDER
17HeadacheCanada Vigilance: 2Canada Vigilance
18Hemorrhage6123488CTD
19Hyperalgesia7908645
20601862		CTD
20HypersensitivityCanada Vigilance: 1Canada Vigilance
21Hypokinesia989390CTD
22Hypotension, Orthostatic3178477
6726371		CTD
23Intraoperative Complications9564401CTD
24Kidney Diseases11576345CTD
25Muscle Rigidity14172950CTD
26Myocardial Infarction991929CTD
27Myoclonus37558CTD
28NauseaCanada Vigilance: 3Canada Vigilance
29Necrosis6123488CTD
30Pain20846436CTD
31PalpitationsCanada Vigilance: 2Canada Vigilance
32Paraganglioma21318381CTD
33Personality Disorders575199CTD
34Pheochromocytoma9564401
15166586		CTD
35Prenatal Exposure Delayed Effects15166586CTD
36Prostatic Hyperplasia1373456
2459421		CTD
37Pulmonary HypertensionCanada Vigilance: 1Canada Vigilance
38Reflex, Abnormal3798479CTD
39Respiratory Distress Syndrome, Newborn15166586CTD
40Sarcoma, Experimental6123488CTD
41Shock, Hemorrhagic998147CTD
42Shock4140426CTD
43SomnolenceCanada Vigilance: 3Canada Vigilance
SIDER
44TachycardiaCanada Vigilance: 11238330
2894880		CTD
SIDER
Canada Vigilance
45Tremor14172950CTD
46Urinary Incontinence7459779CTD
47Urinary Retention3178477
12903414		CTD
48Vasospasm, Intracranial10953871CTD
49Ventricular Fibrillation6103072
6655564		CTD
50VomitingCanada Vigilance: 1Canada Vigilance
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