Probucol
(FYPMFJGVHOHGLL-UHFFFAOYSA-N)
Structure
- SMILES
- CC(Sc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(Sc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)C
- Type(s)
- Approved; Investigational
- ATC code(s)
- C10AX02
- Molecular Formula:
- C31H48O2S2
- Molecular Weight:
- 516.842
- Log P:
- 9.9083
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 2
- TPSA:
- 91.06
- CAS Number(s):
- 23288-49-5
Synonym(s)
1.
Probucol
2.
Biphenabid
3.
DH-581
4.
Lorelco
5.
Lurselle
6.
Panavir
7.
Superlipid
8.
DH 581
9.
DH581
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Blood cholesterol increased | FAERS: 1 | US FAERS | |
| 2 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 3 | Malaise | FAERS: 1 | US FAERS | |
| 4 | Albuminuria | 9527400 | CTD | |
| 5 | Ascites | 8205698 | CTD | |
| 6 | Atherosclerosis | CTD | ||
| 7 | Cardiomegaly | 30240538 | CTD | |
| 8 | Cardiomyopathies | CTD | ||
| 9 | Edema | 9862172 | CTD | |
| 10 | Endomyocardial Fibrosis | 30240538 | CTD | |
| 11 | Granuloma | 2318380 | CTD | |
| 12 | Heart Diseases | 12879278 | CTD | |
| 13 | Heart failure | 10888230 10912462 | CTD | |
| 14 | Hemorrhage | 15683744 | CTD | |
| 15 | Hepatomegaly | 11814474 | CTD | |
| 16 | Hypercholesterolemia | CTD | ||
| 17 | Liver Neoplasms, Experimental | 12014681 | CTD | |
| 18 | Long QT Syndrome | CTD | ||
| 19 | Lysosomal Storage Diseases | 28551711 | CTD | |
| 20 | Nephrosis | 8583697 | CTD | |
| 21 | Nephrotic Syndrome | 2256470 | CTD | |
| 22 | Proteinuria | 7731104 8583697 8959623 | CTD | |
| 23 | Signs and Symptoms, Digestive | 8593127 | CTD | |
| 24 | Syncope | 8022053 | CTD | |
| 25 | Tachycardia | 8644599 15683744 | CTD | |
| 26 | Torsades de Pointes | CTD | ||
| 27 | Ventricular Dysfunction, Left | 8205698 | CTD | |
| 28 | Ventricular Fibrillation | 95312 4197360 | CTD | |
| 29 | Weight Gain | 11814474 | CTD |
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