MetaADEDB 2.0 @ LMMD
Amputation
(UMLS:C0002688)
Definition:
The removal of a limb or other appendage or outgrowth of the body. (Dorland, 28th ed)
UMLS ID:
C0002688
MeSH ID:
D000671
Classification:
Name:
urgical Procedures, Operative
MeSH Tree Number(s):
E04.555.080
Synonym(s)
1.
Amputation
2.
AMPUTATION
3.
Amputation - action
4.
Amputation, NOS
5.
Amputation, not otherwise specified
6.
amputation
7.
amputation procedure
8.
amputations
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1CanagliflozinFAERS: 279
Canada Vigilance: 7		Canada Vigilance
US FAERS
2OlanzapineFAERS: 17US FAERS
3Insulin GlargineFAERS: 13US FAERS
4BosentanFAERS: 8OFFSIDES
US FAERS
5InvokametFAERS: 7US FAERS
6rofecoxibFAERS: 6OFFSIDES
US FAERS
7CinacalcetFAERS: 5US FAERS
8PregabalinFAERS: 5US FAERS
9ALANINE, 3-(p-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-, MONOHYDROCHLORIDE, L-FAERS: 4US FAERS
10AtorvastatinFAERS: 4US FAERS
11RosiglitazoneFAERS: 4US FAERS
12TeriparatideFAERS: 4US FAERS
13WarfarinFAERS: 4US FAERS
14ambrisentanFAERS: 4US FAERS
152-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triolFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
16AlprostadilFAERS: 3US FAERS
17AprotininFAERS: 3US FAERS
18FentanylFAERS: 3US FAERS
19Imatinib MesylateFAERS: 3US FAERS
20LenalidomideFAERS: 3US FAERS
21MelphalanFAERS: 3OFFSIDES
US FAERS
22TacrolimusFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
23bivalirudinFAERS: 3US FAERS
24AripiprazoleFAERS: 2US FAERS
25Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationFAERS: 2US FAERS
26DroxidopaFAERS: 2US FAERS
27ExenatideFAERS: 2US FAERS
28InsulinFAERS: 2US FAERS
29MethotrexateFAERS: 2US FAERS
30RanolazineFAERS: 2US FAERS
31RisperidoneFAERS: 2OFFSIDES
US FAERS
32RivaroxabanFAERS: 2US FAERS
33SynjardyFAERS: 2US FAERS
34ThalidomideFAERS: 2US FAERS
35TriamcinoloneFAERS: 2US FAERS
36acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamideFAERS: 2US FAERS
37benazeprilFAERS: 2US FAERS
38reviparinFAERS: 2US FAERS
394-[(1R)-2-[6-[2-[(2,6-Dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanolFAERS: 1US FAERS
40AMG-416FAERS: 1US FAERS
41Abiraterone AcetateFAERS: 1US FAERS
42AlprazolamFAERS: 1US FAERS
43AmlodipineFAERS: 1US FAERS
44ArthrotecFAERS: 1US FAERS
45AzathioprineFAERS: 1US FAERS
46CarbamazepineFAERS: 1US FAERS
47ClonazepamFAERS: 1US FAERS
48ClozapineFAERS: 1US FAERS
49CyclosporineFAERS: 1US FAERS
50Dapagliflozin and metformin hydrochlorideFAERS: 1US FAERS
51DaptomycinFAERS: 1US FAERS
52DasatinibFAERS: 1US FAERS
53DeferasiroxFAERS: 1US FAERS
54Diovan HctFAERS: 1US FAERS
55EpinephrineFAERS: 1US FAERS
56FluoxetineFAERS: 1US FAERS
57FurosemideFAERS: 1US FAERS
58GabapentinFAERS: 1US FAERS
59Glatiramer AcetateFAERS: 1US FAERS
60HydrochlorothiazideFAERS: 1US FAERS
61Ibandronic AcidFAERS: 1US FAERS
62IloprostFAERS: 1US FAERS
63Insulin DetemirFAERS: 1US FAERS
64Insulin degludecFAERS: 1US FAERS
65Ketorolac TromethamineFAERS: 1US FAERS
66LCZ 696FAERS: 1US FAERS
67LevetiracetamFAERS: 1US FAERS
68LinezolidFAERS: 1OFFSIDES
US FAERS
69MeprobamateFAERS: 1US FAERS
70Mycophenolic AcidFAERS: 1US FAERS
71OmeprazoleFAERS: 1US FAERS
72PCI 32765FAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
73PhenytoinFAERS: 1US FAERS
74PolidocanolFAERS: 1US FAERS
75PropofolFAERS: 1US FAERS
76RopivacaineFAERS: 1US FAERS
77RosiglitazoneFAERS: 1US FAERS
78SorafenibFAERS: 1US FAERS
79TamoxifenFAERS: 1US FAERS
80Tiotropium BromideFAERS: 1US FAERS
81Trimethoprim, Sulfamethoxazole Drug CombinationFAERS: 1US FAERS
82VareniclineFAERS: 1US FAERS
83VemurafenibFAERS: 1US FAERS
84VoriconazoleFAERS: 1US FAERS
85apremilastFAERS: 1US FAERS
86empagliflozinFAERS: 1US FAERS
87gadodiamideFAERS: 1US FAERS
88gemcitabineFAERS: 1US FAERS
89isosorbide-5-mononitrateFAERS: 1US FAERS
90ledipasvir, sofosbuvir drug combinationFAERS: 1US FAERS
91liposomal amphotericin BFAERS: 1US FAERS
92macitentanFAERS: 1US FAERS
93nefazodoneFAERS: 1US FAERS
94saxagliptinFAERS: 1US FAERS
95selexipagFAERS: 1US FAERS
96telithromycinFAERS: 1US FAERS
97tofacitinibFAERS: 1US FAERS
98valdecoxibFAERS: 1US FAERS
99AcitretinOFFSIDES
100AlbuterolOFFSIDES
101AmiodaroneOFFSIDES
102Brimonidine TartrateOFFSIDES
103CalcitriolOFFSIDES
104FluticasoneOFFSIDES
105FulvestrantOFFSIDES
106Lanthanum carbonate hydrateOFFSIDES
107Methylprednisolone AcetateOFFSIDES
108PamidronateOFFSIDES
109PyridoxineOFFSIDES
110Quetiapine FumarateOFFSIDES
111TobramycinOFFSIDES
112TravoprostOFFSIDES
113VancomycinOFFSIDES
114VerapamilOFFSIDES
115Zoledronic AcidCanada Vigilance: 1Canada Vigilance
OFFSIDES
116gadobenic acidOFFSIDES
117gadodiamideOFFSIDES
118gadoteridolOFFSIDES
119gadoversetamideOFFSIDES
120glimepirideOFFSIDES
121zopicloneOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Arthrodesis42.9%
2Osteotomy42.9%
3Traction42.9%
4Synovectomy42.9%
5Tenodesis34.9%
6Cementoplasty28.6%
7Arthroscopy25.6%
8Debridement23.1%
9Extracorporeal Circulation23.1%
10Laparotomy23.1%
11Mastectomy23.1%
12Splenectomy23.1%
13Fasciotomy23.1%
14Fasciectomy23.1%
15Prosthesis Implantation23.1%
16Cytoreductive Surgery23.1%
17Pneumonectomy22%
18Vertebroplasty20.5%
19Dacryocystorhinostomy19%
20Gastroenterostomy19%
21Gastrostomy19%
22Hypophysectomy19%
23Radical Neck Dissection19%
24Thoracostomy19%
25Neck Dissection19%
26Cholecystostomy16.3%
27Salpingostomy16.3%
28Decompressive Craniectomy16.3%
29Deep Brain Stimulation15%
30Cystostomy14.9%
31Adenoidectomy14.3%
32Adrenalectomy14.3%
33Appendectomy14.3%
34Cardiopulmonary Bypass14.3%
35Colectomy14.3%
36Craniotomy14.3%
37Gastrectomy14.3%
38Hepatectomy14.3%
39Hysterotomy14.3%
40Laryngectomy14.3%
41Simple mastectomy14.3%
42Pancreatectomy14.3%
43Thoracotomy14.3%
44Thymectomy14.3%
45Thyroidectomy14.3%
46Tonsillectomy14.3%
47Vitrectomy14.3%
48Parathyroidectomy14.3%
49Pancreaticoduodenectomy14.3%
50Pallidotomy14.3%
51Craniectomy14.3%
52Foraminotomy14.3%
53Neurectomy14.3%
54Iridectomy14.3%
55Thyroplasty14.3%
56Gastroplasty13.9%
57Duodenostomy13.6%
58Pericardiotomy13.6%
59Proctocolectomy13.6%
60Tubal Ligation13.6%
61Gastric Bypass13.6%
62Salpingo-oophorectomy13.2%
63Vasectomy12.4%
64Percutaneous Coronary Intervention12.4%
65rhinoplasty12.3%
66Mediastinoscopy12%
67Colposcopy11.3%
68Hysteroscopy11.3%
69Endarterectomy10.3%
70Episiotomy10.3%
71Goniotomy10.3%
72Hysterectomy10.3%
73Modified radical mastectomy10.3%
74Myringoplasty10.3%
75Nephrectomy10.3%
76Stapedectomy10.3%
77Trabeculectomy10.3%
78Salpingectomy10.3%
79Tympanoplasty10.3%
80Thromboendarterectomy10.3%
81Embolectomy10.3%
82Thrombectomy10.3%
83Pyelotomy10.3%
84Vulvectomy10.3%
85Mastoidectomy10.3%
86Surgical Stapling10.3%
87Posterior Capsulotomy10.3%
88Myomectomy10.3%
89Keratoplasty10.1%
90Lithotripsy10%
91Laser Therapy10%
92Extracorporeal Membrane Oxygenation9.5%
93Glossectomy9.5%
94Laryngoscopy9.5%
95Leukotomy9.5%
96Tooth Extraction9.5%
97Radiofrequency Ablation9.5%
98Photopheresis9.2%
99Carotid Endarterectomy8.5%
100Vaginal hysterectomy8.5%
101Nephroureterectomy8.5%
102Prostatectomy8.5%
103Sympathectomy8.5%
104Orchidopexy8.5%
105Cervicectomy8.5%
106Artificial rupture of membranes8.5%
107Bronchoscopy8.1%
108Cystoscopy8.1%
109Paracentesis8%
110Angioplasty7.6%
111Vagotomy7.6%
112Gingivectomy7.1%
113Preoperative Care7%
114Dermabrasion7%
115Electrocoagulation7%
116Face Lift7%
117Postoperative Care6.8%
118Alveoloplasty6.8%
119Nerve Block6.8%
120Laparoscopy6.7%
121Atherectomy6.3%
122colonoscopy6.2%
123Proctoscopy6.2%
124Endoscopic Retrograde Cholangiopancreatography5.1%
125Biopsy5.1%
126venipuncture4%
127Amniocentesis2.5%
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