gadoteridol
(DPNNNPAKRZOSMO-UHFFFAOYSA-K)
Structure
- SMILES
- CC(CN1CCN(CCN(CCN(CC1)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])O.[Gd+3]
- Type(s)
- Approved; Investigational
- ATC code(s)
- V08CA04
- Molecular Formula:
- C17H29GdN4O7
- Molecular Weight:
- 558.685
- Log P:
- -6.4099
- Hydrogen Bond Acceptor:
- 11
- Hydrogen Bond Donor:
- 1
- TPSA:
- 153.58
- CAS Number(s):
- 120066-54-8
Synonym(s)
1.
gadoteridol
2.
Gd(DO3A)
3.
Gd-HP-D03A
4.
Gd-HP-DO3A
5.
Gd-HPDO3A
6.
Gd-hydroxypropyl-D03A
7.
GdHPDO3A
8.
Prohance
9.
SQ 32,692
10.
SQ 32692
11.
SQ-32692
12.
gadolinium 1,4,7-tris(carboxymethyl)-10-(2'-hydroxypropyl)-1,4,7,10-tetraazacyclododecane
13.
gadolinium 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane
14.
gadolinium HP-DO3A
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 59 | SIDER US FAERS | |
| 2 | Hypersensitivity | FAERS: 55 | SIDER US FAERS | |
| 3 | Vomiting | FAERS: 36 | SIDER US FAERS | |
| 4 | Shock | FAERS: 34 | SIDER US FAERS | |
| 5 | Urticaria | FAERS: 34 | SIDER US FAERS | |
| 6 | Anaphylactic shock | FAERS: 26 | SIDER US FAERS | |
| 7 | Dizziness | FAERS: 22 | SIDER US FAERS | |
| 8 | Sneezing | FAERS: 20 | US FAERS | |
| 9 | Contrast media reaction | FAERS: 18 | US FAERS | |
| 10 | Hypotension | FAERS: 18 | SIDER US FAERS | |
| 11 | Pruritus | FAERS: 17 | SIDER US FAERS | |
| 12 | Anaphylactoid Reaction | FAERS: 15 | SIDER US FAERS | |
| 13 | Erythema | FAERS: 12 | OFFSIDES SIDER US FAERS | |
| 14 | Pallor | FAERS: 12 | US FAERS | |
| 15 | Burning sensation | FAERS: 11 | OFFSIDES US FAERS | |
| 16 | Tremor | FAERS: 11 | SIDER US FAERS | |
| 17 | Cold sweat | FAERS: 10 | US FAERS | |
| 18 | Malaise | FAERS: 10 | SIDER US FAERS | |
| 19 | Asthenia | FAERS: 9 | OFFSIDES US FAERS | |
| 20 | Throat irritation | FAERS: 9 | US FAERS | |
| 21 | Respiratory arrest | FAERS: 8 | US FAERS | |
| 22 | Urinary Incontinence | FAERS: 8 | SIDER US FAERS | |
| 23 | Cardiac Arrest | FAERS: 7 | SIDER US FAERS | |
| 24 | Chest discomfort | FAERS: 7 | US FAERS | |
| 25 | Feeling abnormal | FAERS: 7 | SIDER US FAERS | |
| 26 | Pain | FAERS: 7 | OFFSIDES SIDER US FAERS | |
| 27 | Syncope | FAERS: 7 | SIDER US FAERS | |
| 28 | Arthralgia | FAERS: 6 | US FAERS | |
| 29 | Back Pain | FAERS: 6 | US FAERS | |
| 30 | Chest Pain | FAERS: 6 | SIDER US FAERS | |
| 31 | Chills | FAERS: 6 | US FAERS | |
| 32 | Contrast media allergy | FAERS: 6 | US FAERS | |
| 33 | Depressed Level of Consciousness | FAERS: 6 | SIDER US FAERS | |
| 34 | Drug ineffective | FAERS: 6 | US FAERS | |
| 35 | Fatigue | FAERS: 6 | OFFSIDES US FAERS | |
| 36 | Flushing | FAERS: 6 | SIDER US FAERS | |
| 37 | Lethargy | FAERS: 6 | US FAERS | |
| 38 | No adverse event | FAERS: 6 | US FAERS | |
| 39 | Wheezing | FAERS: 6 | SIDER US FAERS | |
| 40 | Abdominal Pain | FAERS: 5 | SIDER US FAERS | |
| 41 | Biopsy bone abnormal | FAERS: 5 | US FAERS | |
| 42 | Biopsy brain abnormal | FAERS: 5 | US FAERS | |
| 43 | Cyanosis | FAERS: 5 | SIDER US FAERS | |
| 44 | Disorientation | FAERS: 5 | US FAERS | |
| 45 | Headache | FAERS: 5 | SIDER US FAERS | |
| 46 | Retching | FAERS: 5 | US FAERS | |
| 47 | Tachycardia | FAERS: 5 | US FAERS | |
| 48 | Unresponsive to stimuli | FAERS: 5 | US FAERS | |
| 49 | Aphonia | FAERS: 4 | US FAERS | |
| 50 | Bronchospasm | FAERS: 4 | US FAERS | |
| 51 | Dysphonia | FAERS: 4 | US FAERS | |
| 52 | Feeling Cold | FAERS: 4 | US FAERS | |
| 53 | Foaming at mouth | FAERS: 4 | US FAERS | |
| 54 | Musculoskeletal stiffness | FAERS: 4 | OFFSIDES SIDER US FAERS | |
| 55 | Amnesia | FAERS: 3 | US FAERS | |
| 56 | Angioedema | FAERS: 3 | US FAERS | |
| 57 | Anxiety | FAERS: 3 | OFFSIDES SIDER US FAERS | |
| 58 | Bone pain | FAERS: 3 | OFFSIDES US FAERS | |
| 59 | Bradycardia | FAERS: 3 | SIDER US FAERS | |
| 60 | Cerebrovascular accident | FAERS: 3 | US FAERS | |
| 61 | Dysgeusia | FAERS: 3 | SIDER US FAERS | |
| 62 | Eye irritation | FAERS: 3 | US FAERS | |
| 63 | Lip swelling | FAERS: 3 | US FAERS | |
| 64 | Myalgia | FAERS: 3 | US FAERS | |
| 65 | Myocardial Infarction | FAERS: 3 | US FAERS | |
| 66 | Palpitations | FAERS: 3 | US FAERS | |
| 67 | Retrograde amnesia | FAERS: 3 | OFFSIDES US FAERS | |
| 68 | Upper respiratory tract congestion | FAERS: 3 | US FAERS | |
| 69 | Abdominal discomfort | FAERS: 2 | OFFSIDES US FAERS | |
| 70 | Acute kidney injury | FAERS: 2 | US FAERS | |
| 71 | Acute respiratory failure | FAERS: 2 | US FAERS | |
| 72 | Amaurosis | FAERS: 2 | US FAERS | |
| 73 | Asphyxia | FAERS: 2 | US FAERS | |
| 74 | Biopsy skin abnormal | FAERS: 2 | US FAERS | |
| 75 | Blindness | FAERS: 2 | US FAERS | |
| 76 | Blood glucose decreased | FAERS: 2 | US FAERS | |
| 77 | Choking | FAERS: 2 | US FAERS | |
| 78 | Constipation | FAERS: 2 | US FAERS | |
| 79 | Dermatitis | FAERS: 2 | SIDER US FAERS | |
| 80 | Electromechanical dissociation | FAERS: 2 | OFFSIDES US FAERS | |
| 81 | Epilepsy | FAERS: 2 | US FAERS | |
| 82 | Head discomfort | FAERS: 2 | US FAERS | |
| 83 | Infusion site phlebitis | FAERS: 2 | US FAERS | |
| 84 | Limb discomfort | FAERS: 2 | US FAERS | |
| 85 | Memory impairment | FAERS: 2 | US FAERS | |
| 86 | Muscle Rigidity | FAERS: 2 | US FAERS | |
| 87 | Musculoskeletal chest pain | FAERS: 2 | US FAERS | |
| 88 | Pneumothorax | FAERS: 2 | US FAERS | |
| 89 | Presyncope | FAERS: 2 | US FAERS | |
| 90 | Product impurity | FAERS: 2 | US FAERS | |
| 91 | Product quality issue | FAERS: 2 | US FAERS | |
| 92 | Rales | FAERS: 2 | US FAERS | |
| 93 | Respiratory distress | FAERS: 2 | US FAERS | |
| 94 | Rhonchi | FAERS: 2 | US FAERS | |
| 95 | Somnolence | FAERS: 2 | US FAERS | |
| 96 | Stridor | FAERS: 2 | US FAERS | |
| 97 | Toxicity to various agents | FAERS: 2 | US FAERS | |
| 98 | Urticarial vasculitis | FAERS: 2 | US FAERS | |
| 99 | Ventricular Fibrillation | FAERS: 2 | US FAERS | |
| 100 | Visual Impairment | FAERS: 2 | US FAERS | |
| 101 | Visual acuity reduced transiently | FAERS: 2 | OFFSIDES US FAERS | |
| 102 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 103 | Abscess | FAERS: 1 | US FAERS | |
| 104 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 105 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 106 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 107 | Anuria | FAERS: 1 | US FAERS | |
| 108 | Asthma | FAERS: 1 | US FAERS | |
| 109 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 110 | Blood pressure immeasurable | FAERS: 1 | US FAERS | |
| 111 | Cerebral Infarction | FAERS: 1 | US FAERS | |
| 112 | Contraindicated product administered | FAERS: 1 | US FAERS | |
| 113 | Contrast media deposition | FAERS: 1 | US FAERS | |
| 114 | Croup infectious | FAERS: 1 | US FAERS | |
| 115 | Drooling | FAERS: 1 | US FAERS | |
| 116 | Electrocardiogram abnormal | FAERS: 1 | US FAERS | |
| 117 | Electromagnetic interference | FAERS: 1 | US FAERS | |
| 118 | Embolism | FAERS: 1 | US FAERS | |
| 119 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 120 | Exposure during breast feeding | FAERS: 1 | US FAERS | |
| 121 | Eye inflammation | FAERS: 1 | US FAERS | |
| 122 | Eye pain | FAERS: 1 | US FAERS | |
| 123 | Feeling jittery | FAERS: 1 | US FAERS | |
| 124 | Flank Pain | FAERS: 1 | US FAERS | |
| 125 | Hoarseness | FAERS: 1 | US FAERS | |
| 126 | Hyperventilation | FAERS: 1 | US FAERS | |
| 127 | Hypoxia | FAERS: 1 | US FAERS | |
| 128 | Inappropriate affect | FAERS: 1 | US FAERS | |
| 129 | Incoherent | FAERS: 1 | US FAERS | |
| 130 | Incontinence | FAERS: 1 | US FAERS | |
| 131 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 132 | Incorrect route of product administration | FAERS: 1 | US FAERS | |
| 133 | Increased upper airway secretion | FAERS: 1 | US FAERS | |
| 134 | Inflammation | FAERS: 1 | US FAERS | |
| 135 | Injection site inflammation | FAERS: 1 | US FAERS | |
| 136 | Joint destruction | FAERS: 1 | US FAERS | |
| 137 | Lip pruritus | FAERS: 1 | US FAERS | |
| 138 | Mental status changes | FAERS: 1 | US FAERS | |
| 139 | Metastasis | FAERS: 1 | US FAERS | |
| 140 | Mouth swelling | FAERS: 1 | US FAERS | |
| 141 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 142 | Nasal discomfort | FAERS: 1 | US FAERS | |
| 143 | Nasal pruritus | FAERS: 1 | US FAERS | |
| 144 | Nephrogenic Fibrosing Dermopathy | FAERS: 1 | OFFSIDES US FAERS | |
| 145 | Nervousness | FAERS: 1 | US FAERS | |
| 146 | Oculogyric crisis | FAERS: 1 | US FAERS | |
| 147 | Onychalgia | FAERS: 1 | US FAERS | |
| 148 | Orthostatic tremor | FAERS: 1 | US FAERS | |
| 149 | Petechiae | FAERS: 1 | US FAERS | |
| 150 | Procedural complication | FAERS: 1 | US FAERS | |
| 151 | Productive Cough | FAERS: 1 | US FAERS | |
| 152 | Quality of life decreased | FAERS: 1 | OFFSIDES US FAERS | |
| 153 | Reflux laryngitis | FAERS: 1 | US FAERS | |
| 154 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 155 | Restlessness | FAERS: 1 | US FAERS | |
| 156 | Seizure like phenomena | FAERS: 1 | US FAERS | |
| 157 | Septic Shock | FAERS: 1 | US FAERS | |
| 158 | Shock symptom | FAERS: 1 | US FAERS | |
| 159 | Sinoatrial Block | FAERS: 1 | US FAERS | |
| 160 | Skin discomfort | FAERS: 1 | US FAERS | |
| 161 | Skin tightness | FAERS: 1 | OFFSIDES US FAERS | |
| 162 | Stomatitis | FAERS: 1 | US FAERS | |
| 163 | Tetany | FAERS: 1 | US FAERS | |
| 164 | Thrombosis in device | FAERS: 1 | US FAERS | |
| 165 | Toothache | FAERS: 1 | US FAERS | |
| 166 | Tracheal Stenosis | FAERS: 1 | US FAERS | |
| 167 | Urinary Retention | FAERS: 1 | US FAERS | |
| 168 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 169 | Vascular pain | FAERS: 1 | US FAERS | |
| 170 | Wrong technique in product usage process | FAERS: 1 | US FAERS | |
| 171 | Yawning | FAERS: 1 | OFFSIDES US FAERS | |
| 172 | Abasia | OFFSIDES | ||
| 173 | Abdominal Cramps | SIDER | ||
| 174 | Activities of daily living impaired | OFFSIDES | ||
| 175 | Adverse event | OFFSIDES | ||
| 176 | Amputation | OFFSIDES | ||
| 177 | Anhedonia | OFFSIDES | ||
| 178 | Arthritis | OFFSIDES | ||
| 179 | Arthropathy | OFFSIDES | ||
| 180 | Bereavement | OFFSIDES | ||
| 181 | Bone density decreased | OFFSIDES | ||
| 182 | Bronchopneumonia | OFFSIDES | ||
| 183 | Calcinosis | OFFSIDES | ||
| 184 | Catheter site erythema | OFFSIDES | ||
| 185 | Contracture | OFFSIDES | ||
| 186 | Demyelination | OFFSIDES | ||
| 187 | Discomfort | SIDER | ||
| 188 | Dry skin | OFFSIDES | ||
| 189 | Emotional distress | OFFSIDES | ||
| 190 | Eschar | OFFSIDES | ||
| 191 | Excoriation | OFFSIDES | ||
| 192 | Exfoliative rash | OFFSIDES | ||
| 193 | Extremity contracture | OFFSIDES | ||
| 194 | Eye Infection | OFFSIDES | ||
| 195 | Eye Redness | OFFSIDES | ||
| 196 | Formication | OFFSIDES | ||
| 197 | General physical health deterioration | OFFSIDES | ||
| 198 | Gingivitis | SIDER | ||
| 199 | Granuloma | OFFSIDES | ||
| 200 | Hyperkeratosis | OFFSIDES | ||
| 201 | Hyperpigmentation | OFFSIDES | ||
| 202 | Hypertensive emergency | OFFSIDES | ||
| 203 | Impaired self-care | OFFSIDES | ||
| 204 | Impaired work ability | OFFSIDES | ||
| 205 | Induration | OFFSIDES | ||
| 206 | Infusion site mobility decreased | OFFSIDES | ||
| 207 | Injection Site Reaction | SIDER | ||
| 208 | Injection site pain | SIDER | ||
| 209 | Joint Range of Motion Decreased | OFFSIDES | ||
| 210 | Joint stiffness | OFFSIDES | ||
| 211 | Laryngospasm | SIDER | ||
| 212 | Lichenification | OFFSIDES | ||
| 213 | Life expectancy shortened | OFFSIDES | ||
| 214 | Livedo Reticularis | OFFSIDES | ||
| 215 | Lymphedema | OFFSIDES | ||
| 216 | Metaplasia | OFFSIDES | ||
| 217 | Muscle Fatigue | OFFSIDES | ||
| 218 | Muscle Weakness | OFFSIDES | ||
| 219 | Muscle fibrosis | OFFSIDES | ||
| 220 | Muscle tightness | OFFSIDES | ||
| 221 | Musculoskeletal discomfort | OFFSIDES | ||
| 222 | Myocardial fibrosis | OFFSIDES | ||
| 223 | Myosclerosis | OFFSIDES | ||
| 224 | Neck stiffness | SIDER | ||
| 225 | Nephrogenic Systemic Fibrosis | SIDER | ||
| 226 | Neuralgia | OFFSIDES | ||
| 227 | Nodule on extremity | OFFSIDES | ||
| 228 | Nuchal Rigidity | SIDER | ||
| 229 | Ocular icterus | OFFSIDES | ||
| 230 | Open wound | OFFSIDES | ||
| 231 | Pain of skin | OFFSIDES | ||
| 232 | Physical disability | OFFSIDES | ||
| 233 | Pinguecula | OFFSIDES | ||
| 234 | Postoperative renal failure | OFFSIDES | ||
| 235 | Pulmonary function test decreased | OFFSIDES | ||
| 236 | QRS axis abnormal | OFFSIDES | ||
| 237 | Quadriparesis | OFFSIDES | ||
| 238 | Rhinitis | SIDER | ||
| 239 | Sclerodactylia | OFFSIDES | ||
| 240 | Scleroderma | OFFSIDES | ||
| 241 | Skin Erosion | OFFSIDES | ||
| 242 | Skin Induration | OFFSIDES | ||
| 243 | Skin Wrinkling | OFFSIDES | ||
| 244 | Skin hypertrophy | OFFSIDES | ||
| 245 | Skin lesion | OFFSIDES | ||
| 246 | Skin necrosis | OFFSIDES | ||
| 247 | Spinal column stenosis | OFFSIDES | ||
| 248 | Spondylitis | OFFSIDES | ||
| 249 | Staring | SIDER | ||
| 250 | Stasis dermatitis | OFFSIDES | ||
| 251 | Stress | OFFSIDES | ||
| 252 | Stupor | SIDER | ||
| 253 | Subcutaneous nodule | OFFSIDES | ||
| 254 | Sweating | SIDER | ||
| 255 | Tinnitus | SIDER | ||
| 256 | Unevaluable event | OFFSIDES | ||
| 257 | Xerosis | OFFSIDES | ||
| 258 | effusion | OFFSIDES |
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