MetaADEDB 2.0 @ LMMD
Meprobamate
(NPPQSCRMBWNHMW-UHFFFAOYSA-N)
Structure
SMILES
CCCC(COC(=O)N)(COC(=O)N)C
Type(s)
Approved; Illicit
ATC code(s)
N05BC01; N05BC51; N05CX01
Molecular Formula:
C9H18N2O4
Molecular Weight:
218.250
Log P:
2.3840
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
104.64
CAS Number(s):
57-53-4
Synonym(s)
1.
Meprobamate
2.
Dapaz
3.
Equanil
4.
Meprospan
5.
Miltown
6.
Méprobamate Richard
7.
Tranmep
8.
Visano
External Link(s)
MeSHD008620
PubChem Compound4064
ChEBI6761
CHEMBLCHEMBL979
DrugBankDB00371
DrugCentral1704
IUPHAR/BPS Guide to PHARMACOLOGY7225
KEGGdr:D00376
Therapeutic Target DatabaseD0E0GV
D0Y4AW
D0J7DI
ZINC1530701
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 6US FAERS
2Suicide attemptFAERS: 4US FAERS
3Toxicity to various agentsFAERS: 4US FAERS
4Cardiovascular insufficiencyFAERS: 3US FAERS
5OverdoseFAERS: 3OFFSIDES
US FAERS
6Respiratory DepressionFAERS: 3US FAERS
7CyanosisFAERS: 2US FAERS
8Drug exposure during pregnancyFAERS: 2US FAERS
9Drug withdrawal syndromeFAERS: 2US FAERS
10GangreneFAERS: 2US FAERS
11HeadacheFAERS: 2
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
12LeukocytosisFAERS: 2US FAERS
13Product substitution issueFAERS: 2US FAERS
14Wrong technique in drug usage processFAERS: 2OFFSIDES
US FAERS
15AmputationFAERS: 1US FAERS
16AnxietyFAERS: 1US FAERS
17CholelithiasisFAERS: 1US FAERS
18Completed SuicideFAERS: 1OFFSIDES
US FAERS
19Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
20Drug DependenceFAERS: 1US FAERS
21Drug abuseFAERS: 1US FAERS
22Extremity necrosisFAERS: 1US FAERS
23FatigueFAERS: 1US FAERS
24HypersensitivityFAERS: 1SIDER
US FAERS
25HypotensionFAERS: 1
Canada Vigilance: 2		5092569CTD
SIDER
Canada Vigilance
US FAERS
26Incorrect dose administeredFAERS: 1US FAERS
27Incorrect route of drug administrationFAERS: 1US FAERS
28Intentional drug misuseFAERS: 1US FAERS
29LethargyFAERS: 1US FAERS
30Metabolic acidosisFAERS: 1US FAERS
31MyalgiaFAERS: 1US FAERS
32NauseaFAERS: 1
Canada Vigilance: 3		5092569CTD
SIDER
Canada Vigilance
US FAERS
33NecrosisFAERS: 1US FAERS
34No adverse eventFAERS: 1US FAERS
35PalpitationsFAERS: 1SIDER
US FAERS
36Pectus excavatumFAERS: 1US FAERS
37PoisoningFAERS: 1US FAERS
38Product use issueFAERS: 1US FAERS
39SyncopeFAERS: 15092569CTD
SIDER
US FAERS
40TachycardiaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
41TremorFAERS: 1
Canada Vigilance: 3		Canada Vigilance
US FAERS
42Wrong technique in product usage processFAERS: 1US FAERS
43AbuseOFFSIDES
44Accidental deathOFFSIDES
45Accidental overdoseOFFSIDES
46AcidosisOFFSIDES
47Activities of daily living impairedOFFSIDES
48AgeusiaOFFSIDES
49AgitationSIDER
50Agranulocytosis5092569CTD
SIDER
51AkathisiaCanada Vigilance: 1Canada Vigilance
52Alcohol Withdrawal Delirium12809069CTD
53Alcohol consumptionOFFSIDES
54Alcohol interactionOFFSIDES
55Alcohol poisoningOFFSIDES
56Alcohol problemCanada Vigilance: 1Canada Vigilance
57AlkalosisOFFSIDES
58Ammonia increasedOFFSIDES
59Amnesia2900011CTD
60AnalgesiaOFFSIDES
61Anaphylactic shockSIDER
62AngioedemaSIDER
63Ankle FractureOFFSIDES
64Antiviral drug level above therapeuticOFFSIDES
65AnuriaSIDER
66ApathyOFFSIDES
67ApneaOFFSIDES
68ArteriosclerosisOFFSIDES
69Arteriovenous graft thrombosisOFFSIDES
70Aspiration PneumoniaOFFSIDES
71AsterixisOFFSIDES
72AstheniaSIDER
73AtaxiaSIDER
74AtherosclerosisOFFSIDES
75Atrial tachycardiaOFFSIDES
76Basal cell carcinomaOFFSIDES
77Biopsy bone abnormalOFFSIDES
78Blood alcohol increasedOFFSIDES
79Blood creatine phosphokinase increasedOFFSIDES
80Blood creatinine increasedOFFSIDES
81Blood glucose fluctuationOFFSIDES
82Blood osmolarity decreasedOFFSIDES
83Blood sodiumOFFSIDES
84Blood thyroid stimulating hormone increasedOFFSIDES
85Blood urea increasedOFFSIDES
86Body TemperatureOFFSIDES
87Bone fragmentationOFFSIDES
88Bone swellingOFFSIDES
89BradycardiaOFFSIDES
90Bronchial secretion retentionOFFSIDES
91BronchopneumoniaOFFSIDES
92BronchospasmSIDER
93Bulbar palsyOFFSIDES
94Cell DeathOFFSIDES
95CellulitisOFFSIDES
96Central nervous system massOFFSIDES
97Cerebral atrophyOFFSIDES
98Cerebral calcificationOFFSIDES
99Chemotherapeutic drug level increasedOFFSIDES
100Chest wall painOFFSIDES
101Chills5092569CTD
SIDER
102CholangiolitisOFFSIDES
103Chronic left ventricular failureOFFSIDES
104CirrhosisOFFSIDES
105Coagulation factor V level decreasedOFFSIDES
106Colonic Diseases, Functional3489028CTD
107Compulsive sexual behaviourOFFSIDES
108ConfabulationOFFSIDES
109Conjunctival depositOFFSIDES
110Coronary artery insufficiencyOFFSIDES
111Creatinine renal clearance decreasedOFFSIDES
112CryptorchidismOFFSIDES
113Culture positiveOFFSIDES
114Cytolytic hepatitisOFFSIDES
115Cytomegalovirus hepatitisOFFSIDES
116DemyelinationOFFSIDES
117Dental cleaningOFFSIDES
118DermatitisSIDER
119Device FailureOFFSIDES
120DizzinessCanada Vigilance: 1Canada Vigilance
SIDER
121DrowningOFFSIDES
122DrowsinessOFFSIDES
SIDER
123Drug Eruptions5092569CTD
124Drug abuserOFFSIDES
125Drug addictOFFSIDES
126Drug administration errorOFFSIDES
127Drug screen positiveOFFSIDES
128Drug toxicityOFFSIDES
129Dysarthria622433CTD
SIDER
130Dysthymic DisorderOFFSIDES
131EcchymosisSIDER
132Economic problemOFFSIDES
133EmbolismOFFSIDES
134EnteritisOFFSIDES
135EosinophiliaSIDER
136Eosinophilic myocarditisOFFSIDES
137EpilepsyOFFSIDES
138Epstein-Barr virus antibody positiveOFFSIDES
139Epstein-Barr virus test positiveOFFSIDES
140Erectile dysfunctionOFFSIDES
141ErysipelasOFFSIDES
142Erythema MultiformeSIDER
143ErythemaCanada Vigilance: 2Canada Vigilance
OFFSIDES
144Erythrodermic psoriasisOFFSIDES
145ErythrosisOFFSIDES
146Escherichia infectionOFFSIDES
147Escherichia urinary tract infectionOFFSIDES
148Euphoric moodSIDER
149ExcoriationOFFSIDES
150Eyelid DiseasesOFFSIDES
151Failure of implantOFFSIDES
152Feeding disorder neonatalOFFSIDES
153Fever5092569CTD
154Fixed drug eruptionSIDER
155Fluid replacementOFFSIDES
156FlushingCanada Vigilance: 1Canada Vigilance
157Gamma-Glutamyltransferase IncreasedOFFSIDES
158Gastrointestinal toxicityOFFSIDES
159General physical health deteriorationOFFSIDES
160Glasgow coma scaleOFFSIDES
161GranulocytosisOFFSIDES
162HemiplegiaOFFSIDES
163Hepatic congestionOFFSIDES
164Hepatic necrosisOFFSIDES
165HepatitisOFFSIDES
166HepatosplenomegalyOFFSIDES
167High density lipoprotein increasedOFFSIDES
168HyperpyrexiaSIDER
169Hypertensive cardiomyopathyOFFSIDES
170Hypertensive heart diseaseOFFSIDES
171HypotensiveSIDER
172Iatrogenic injuryOFFSIDES
173IncoherentOFFSIDES
174Infantile apnoeic attackOFFSIDES
175Injury asphyxiationOFFSIDES
176Intelligence test abnormalOFFSIDES
177Intentional misuseOFFSIDES
178Intervertebral disc injuryOFFSIDES
179Intestinal infarctionOFFSIDES
180Kidney FailureOFFSIDES
181Leukopenia neonatalOFFSIDES
182LeukopeniaSIDER
183Limb injuryOFFSIDES
184Locked-In SyndromeOFFSIDES
185Lymph node cancer metastaticOFFSIDES
186LymphadenopathySIDER
187LymphedemaOFFSIDES
188Lymphoma, Non-Hodgkin8834551CTD
189MacrocytosisOFFSIDES
190MacroglossiaOFFSIDES
191Malignant neoplasm progressionOFFSIDES
192Maternal alcohol useOFFSIDES
193Medical device painOFFSIDES
194Medication ErrorCanada Vigilance: 1Canada Vigilance
195Mental disorders17033575CTD
196Metastases to adrenalsOFFSIDES
197Modified radical mastectomyOFFSIDES
198Motor retardationOFFSIDES
199Multiple MyelomaOFFSIDES
200Multiple drug overdoseOFFSIDES
201Multiple drug overdose intentionalOFFSIDES
202Myocardial fibrosisOFFSIDES
203Myoglobin blood increasedOFFSIDES
204ObstructionOFFSIDES
205OliguriaSIDER
206OrthopneaOFFSIDES
207OsteopeniaOFFSIDES
208PCO2 decreasedOFFSIDES
209Pancytopenia5092569CTD
210Parvovirus B19 serology positiveOFFSIDES
211PetechiaeSIDER
212Pneumatosis Cystoides IntestinalisOFFSIDES
213PneumoconiosisOFFSIDES
214Polysubstance abuseOFFSIDES
215Poor sucking reflexOFFSIDES
216Post-anoxic myoclonusOFFSIDES
217Postoperative thrombosisOFFSIDES
218ProctitisSIDER
219Product physical issueCanada Vigilance: 1Canada Vigilance
220Protein total increasedOFFSIDES
221Prothrombin level abnormalOFFSIDES
222Prothrombin time ratio decreasedOFFSIDES
223PruritusCanada Vigilance: 45092569CTD
SIDER
Canada Vigilance
224PseudarthrosisOFFSIDES
225Psychotic Disorders5092569CTD
226Pulmonary congestionOFFSIDES
227PurpuraCanada Vigilance: 15092569CTD
SIDER
Canada Vigilance
228Radicular painOFFSIDES
229RalesOFFSIDES
230Reduced facial expressionCanada Vigilance: 1Canada Vigilance
231Respiratory FailureCanada Vigilance: 1Canada Vigilance
232RestlessnessCanada Vigilance: 1Canada Vigilance
233RhabdomyolysisOFFSIDES
234Rhinovirus infectionOFFSIDES
235SchizophreniaOFFSIDES
236ScreamingOFFSIDES
237Seizures1803
2978064		CTD
238Sensorimotor disorderOFFSIDES
239ShockSIDER
240Skin lacerationOFFSIDES
241Skin necrosisOFFSIDES
242Sleep Wake Disorders17033575CTD
243Slurred speechSIDER
244SnoringOFFSIDES
245SomnolenceCanada Vigilance: 2Canada Vigilance
SIDER
246Spondylitic myelopathyOFFSIDES
247Stevens-Johnson SyndromeSIDER
248StomatitisSIDER
249Substance Withdrawal Syndrome5092569
5714910
5714911		CTD
250Substance-Related Disorders8438828
18792430		CTD
251Sudden deathOFFSIDES
252SynovitisOFFSIDES
253Therapeutic product ineffectiveOFFSIDES
254Thrombocytopenia5092569CTD
255Thrombocytopenic purpuraSIDER
256Tonic clonic movementsOFFSIDES
257Toxicologic test abnormalOFFSIDES
258Toxoplasma serologyOFFSIDES
259Transferrin decreasedOFFSIDES
260Troponin increasedOFFSIDES
261UrticariaCanada Vigilance: 45092569CTD
Canada Vigilance
262Vascular purpuraSIDER
263Vertigo5070302CTD
SIDER
264Victim of sexual abuseOFFSIDES
265Viral labyrinthitisOFFSIDES
266Vomiting5092569CTD
SIDER
267Vulvovaginal discomfortOFFSIDES
268Vulvovaginal painCanada Vigilance: 1Canada Vigilance
269Wound InfectionOFFSIDES
270Wrong drug administeredOFFSIDES
271effusionOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.