MetaADEDB 2.0 @ LMMD
eicosapentaenoic acid ethyl ester
(SSQPWTVBQMWLSZ-AAQCHOMXSA-N)
Structure
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCC
Type(s)
Approved; Investigational; Nutraceutical
Molecular Formula:
C22H34O2
Molecular Weight:
330.504
Log P:
6.4712
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
26.3
CAS Number(s):
86227-47-6
Synonym(s)
1.
eicosapentaenoic acid ethyl ester
2.
5,8,11,14,17-eicosapentaenoic acid, ethyl ester, (5Z,8Z,11Z,14Z,17Z)-
3.
AMR-101
4.
AMR101
5.
EPA-E
6.
Epadel
7.
ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
8.
ethyl all-cis-5,8,11,14,17-icosapentaenoate
9.
ethyl eicosapentaenoate
10.
ethyl icosapentaenoate
11.
icosapent ethyl
External Link(s)
MeSHC035276
PubChem Compound9831415
ChEBI84883
80366
CHEMBLCHEMBL2095209
DrugBankDB08887
DrugCentral1413
IUPHAR/BPS Guide to PHARMACOLOGY7441
KEGGcpd:C16184
dr:D01892
Therapeutic Target DatabaseD0G2MW
D0LW5J
D0Q8BT
ZINC3785276
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood triglycerides increasedFAERS: 44OFFSIDES
US FAERS
2Product taste abnormalFAERS: 42US FAERS
3Product physical issueFAERS: 40US FAERS
4ArthralgiaFAERS: 39US FAERS
5EructationFAERS: 24US FAERS
6Drug ineffectiveFAERS: 22US FAERS
7Product adhesion issueFAERS: 22US FAERS
8Abdominal discomfortFAERS: 18US FAERS
9NauseaFAERS: 18US FAERS
10Product use complaintFAERS: 15US FAERS
11DyspepsiaFAERS: 14US FAERS
12Product size issueFAERS: 14US FAERS
13MyalgiaFAERS: 13US FAERS
14DysgeusiaFAERS: 12OFFSIDES
US FAERS
15Abdominal PainFAERS: 10US FAERS
16RetchingFAERS: 10US FAERS
17DizzinessFAERS: 8US FAERS
18FatigueFAERS: 8US FAERS
19PainFAERS: 8US FAERS
20Prescribed underdoseFAERS: 8US FAERS
21Intentional product use issueFAERS: 7US FAERS
22Product coating issueFAERS: 7US FAERS
23Blood glucose increasedFAERS: 6US FAERS
24HeadacheFAERS: 6US FAERS
25Oropharyngeal painFAERS: 6US FAERS
26Wrong technique in product usage processFAERS: 6US FAERS
27FlatulenceFAERS: 5US FAERS
28GoutFAERS: 5US FAERS
29PruritusFAERS: 5US FAERS
30VomitingFAERS: 5US FAERS
31AlopeciaFAERS: 4US FAERS
32Atrial FibrillationFAERS: 4US FAERS
33Chest discomfortFAERS: 4US FAERS
34ChokingFAERS: 4US FAERS
35Drug dose omissionFAERS: 4US FAERS
36Feeling abnormalFAERS: 4US FAERS
37Low density lipoprotein increasedFAERS: 4US FAERS
38MalaiseFAERS: 4US FAERS
39No adverse eventFAERS: 4US FAERS
40Product leakageFAERS: 4US FAERS
41Therapeutic response unexpectedFAERS: 4US FAERS
42Throat irritationFAERS: 4US FAERS
43Wrong technique in drug usage processFAERS: 4US FAERS
44Back PainFAERS: 3US FAERS
45Cerebrovascular accidentFAERS: 3US FAERS
46HypothyroidismFAERS: 3US FAERS
47Inappropriate schedule of drug administrationFAERS: 3US FAERS
48Incorrect dose administeredFAERS: 3US FAERS
49Medication residue presentFAERS: 3US FAERS
50UrticariaFAERS: 3US FAERS
51ArthritisFAERS: 2US FAERS
52Blood cholesterol increasedFAERS: 2US FAERS
53Burning sensationFAERS: 2US FAERS
54Chest PainFAERS: 2US FAERS
55ErythemaFAERS: 2US FAERS
56Foreign body in respiratory tractFAERS: 2US FAERS
57Incorrect product storageFAERS: 2US FAERS
58Intentional dose omissionFAERS: 2US FAERS
59Intentional product misuseFAERS: 2US FAERS
60Joint swellingFAERS: 2US FAERS
61MalabsorptionFAERS: 2US FAERS
62Memory impairmentFAERS: 2US FAERS
63Musculoskeletal PainFAERS: 2US FAERS
64Non-cardiac chest painFAERS: 2US FAERS
65Peripheral swellingFAERS: 2US FAERS
66Prescription drug used without a prescriptionFAERS: 2US FAERS
67Product container issueFAERS: 2US FAERS
68Product physical consistency issueFAERS: 2US FAERS
69SwellingFAERS: 2US FAERS
70Therapy cessationFAERS: 2US FAERS
71Abdominal tendernessFAERS: 1US FAERS
72AcneFAERS: 1US FAERS
73AgitationFAERS: 1US FAERS
74AnxietyFAERS: 1US FAERS
75AphasiaFAERS: 1US FAERS
76Arterial InjuryFAERS: 1US FAERS
77Arterial therapeutic procedureFAERS: 1US FAERS
78Autonomic nervous system imbalanceFAERS: 1US FAERS
79Blood alcohol increasedFAERS: 1US FAERS
80Blood glucose abnormalFAERS: 1US FAERS
81Blood potassium increasedFAERS: 1US FAERS
82Blood thyroid stimulating hormone increasedFAERS: 1US FAERS
83Blood triglycerides abnormalFAERS: 1US FAERS
84BradykinesiaFAERS: 1US FAERS
85ChillsFAERS: 1US FAERS
86Choking sensationFAERS: 1US FAERS
87ChromaturiaFAERS: 1OFFSIDES
US FAERS
88ConstipationFAERS: 1US FAERS
89Deep Vein ThrombosisFAERS: 1US FAERS
90DermatitisFAERS: 1US FAERS
91Diabetes MellitusFAERS: 1US FAERS
92Drug administration errorFAERS: 1US FAERS
93EczemaFAERS: 1US FAERS
94FlushingFAERS: 1US FAERS
95GastrectomyFAERS: 1US FAERS
96Gastrointestinal motility disorderFAERS: 1US FAERS
97General symptomFAERS: 1US FAERS
98HypersensitivityFAERS: 1US FAERS
99Intercepted drug prescribing errorFAERS: 1US FAERS
100Joint stiffnessFAERS: 1US FAERS
101LazinessFAERS: 1US FAERS
102Lip swellingFAERS: 1US FAERS
103MenorrhagiaFAERS: 1US FAERS
104Musculoskeletal stiffnessFAERS: 1US FAERS
105MydriasisFAERS: 1US FAERS
106Myocardial InfarctionFAERS: 1US FAERS
107NervousnessFAERS: 1US FAERS
108Nipple painFAERS: 1US FAERS
109OverdoseFAERS: 1US FAERS
110Pain of skinFAERS: 1US FAERS
111PalpitationsFAERS: 1US FAERS
112Peritonsillar AbscessFAERS: 1US FAERS
113PharyngitisFAERS: 1US FAERS
114PneumoniaFAERS: 1US FAERS
115Poor quality sleepFAERS: 1US FAERS
116Prescribed overdoseFAERS: 1US FAERS
117PresyncopeFAERS: 1US FAERS
118Product container seal issueFAERS: 1US FAERS
119Product difficult to swallowFAERS: 1US FAERS
120Product label confusionFAERS: 1US FAERS
121Product packaging quantity issueFAERS: 1US FAERS
122Product storage errorFAERS: 1US FAERS
123Product tamperingFAERS: 1US FAERS
124Product use issueFAERS: 1US FAERS
125Productive CoughFAERS: 1US FAERS
126Pulmonary EmbolismFAERS: 1US FAERS
127SyncopeFAERS: 1US FAERS
128ToothacheFAERS: 1US FAERS
129TremorFAERS: 1US FAERS
130Viral pharyngitisFAERS: 1US FAERS
131Weight decreasedFAERS: 1US FAERS
132Activities of daily living impairedOFFSIDES
133Adverse eventOFFSIDES
134Alanine aminotransferase abnormalOFFSIDES
135Altered state of consciousnessOFFSIDES
136Aspartate aminotransferase abnormalOFFSIDES
137Aspiration PneumoniaOFFSIDES
138AtaxiaOFFSIDES
139Band neutrophil count increasedOFFSIDES
140Band neutrophil percentage increasedOFFSIDES
141Bed restOFFSIDES
142Blood albumin decreasedOFFSIDES
143Blood amylase increasedOFFSIDES
144Blood amylaseOFFSIDES
145Blood cholesterolOFFSIDES
146Blood creatine phosphokinase increasedOFFSIDES
147Blood elastase increasedOFFSIDES
148Blood lactate dehydrogenase increasedOFFSIDES
149Blood magnesium increasedOFFSIDES
150Blood urea increasedOFFSIDES
151Blood uric acidOFFSIDES
152Cerebral atrophyOFFSIDES
153Disseminated Intravascular CoagulationOFFSIDES
154DysuriaOFFSIDES
155EnteritisOFFSIDES
156Erosive gastritisOFFSIDES
157Erythema MultiformeOFFSIDES
158Fatty LiverOFFSIDES
159Feeling ColdOFFSIDES
160Femoral artery occlusionOFFSIDES
161Fibrin increasedOFFSIDES
162Gamma-Glutamyltransferase IncreasedOFFSIDES
163Gingival HypertrophyOFFSIDES
164GlobulinuriaOFFSIDES
165Heat illnessOFFSIDES
166Histiocytosis haematophagicOFFSIDES
167Ileal ulcerOFFSIDES
168Insulin Resistance14614217CTD
169Intestinal mucosal hypertrophyOFFSIDES
170Intraocular inflammationOFFSIDES
171LipaseOFFSIDES
172Lipoprotein (a) abnormalOFFSIDES
173Myoglobin blood increasedOFFSIDES
174Myoglobin urine presentOFFSIDES
175Nephrogenic Diabetes InsipidusOFFSIDES
176Oropharyngeal discomfortOFFSIDES
177PneumothoraxOFFSIDES
178Protein total decreasedOFFSIDES
179Prothrombin level decreasedOFFSIDES
180Respiratory FailureOFFSIDES
181Skin necrosisOFFSIDES
182Transaminases increasedOFFSIDES
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