MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

temocapril hydrochloride

(FIQOFIRCTOWDOW-BJLQDIEVSA-N)

Structure

SMILES: CCOC(=O)[C@@H](N[C@H]1CS[C@@H](CN(C1=O)CC(=O)O)c1cccs1)CCc1ccccc1
Type(s): Experimental; Investigational
ATC code(s): C09AA14
Molecular Formula:: C23H28N2O5S2
Molecular Weight:: 476.609
Log P:: 3.3007
Hydrogen Bond Acceptor:: 9
Hydrogen Bond Donor:: 2
TPSA:: 149.48
CAS Number(s):: 111902-57-9

Synonym(s)

temocapril hydrochloride

CS 622

CS-622

CS622

alpha-((2S,6R)-6-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl)acetic acid.HCl

temocapril

External Link(s)

MeSH	C055603
PubChem Compound	40466973 443874
ChEBI	135771
CHEMBL	CHEMBL2110627
DrugBank	DB08836
DrugCentral	2586
KEGG	dr:D08566
ZINC	3808778

Adverse Drug Event(s)

	Name	Data Source
1	Acidosis	OFFSIDES
2	Activities of daily living impaired	OFFSIDES
3	Acute intermittent porphyria	OFFSIDES
4	Acute prerenal failure	OFFSIDES
5	Agraphia	OFFSIDES
6	Altered state of consciousness	OFFSIDES
7	Aneurysm	OFFSIDES
8	Anhidrosis	OFFSIDES
9	Anorexia	OFFSIDES
10	Anti-insulin antibody positive	OFFSIDES
11	Anuria	OFFSIDES
12	Aortic Aneurysm	OFFSIDES
13	Apathy	OFFSIDES
14	Blood Glucose	OFFSIDES
15	Blood alkaline phosphatase increased	OFFSIDES
16	Blood calcium abnormal	OFFSIDES
17	Blood chloride decreased	OFFSIDES
18	Blood creatinine increased	OFFSIDES
19	Blood fibrinogen increased	OFFSIDES
20	Blood glucose decreased	OFFSIDES
21	Blood glucose fluctuation	OFFSIDES
22	Blood lactate dehydrogenase increased	OFFSIDES
23	Blood phosphorus increased	OFFSIDES
24	Blood potassium increased	OFFSIDES
25	Blood pressure inadequately controlled	OFFSIDES
26	Blood sodium	OFFSIDES
27	Blood triglycerides decreased	OFFSIDES
28	Blood urea increased	OFFSIDES
29	Colitis	OFFSIDES
30	Conversion disorder	OFFSIDES
31	Depressed Level of Consciousness	OFFSIDES
32	Detachment of retinal pigment epithelium	OFFSIDES
33	Diabetic Nephropathy	OFFSIDES
34	Disseminated Intravascular Coagulation	OFFSIDES
35	Diverticulosis	OFFSIDES
36	Dry skin	OFFSIDES
37	Dyschezia	OFFSIDES
38	Dysuria	OFFSIDES
39	Erythema Multiforme	OFFSIDES
40	Focal glomerulosclerosis	OFFSIDES
41	Gastrointestinal erosion	OFFSIDES
42	Gingival Hypertrophy	OFFSIDES
43	Gingivectomy	OFFSIDES
44	Globulinuria	OFFSIDES
45	Hallucinations, mixed	OFFSIDES
46	Hemiplegia	OFFSIDES
47	Histiocytosis haematophagic	OFFSIDES
48	Immune reconstitution syndrome	OFFSIDES
49	Infection	OFFSIDES
50	Injection site dermatitis	OFFSIDES
51	Intestinal Obstruction	OFFSIDES
52	Intestinal Perforation	OFFSIDES
53	Leukopenia neonatal	OFFSIDES
54	Lymphangiosis carcinomatosa	OFFSIDES
55	Lymphocyte stimulation test positive	OFFSIDES
56	Malabsorption	OFFSIDES
57	Metabolic acidosis	OFFSIDES
58	Myoglobin blood increased	OFFSIDES
59	Nephrotic Syndrome	OFFSIDES
60	Oliguria	OFFSIDES
61	Oropharyngitis fungal	OFFSIDES
62	Overdose	OFFSIDES
63	Paraparesis	OFFSIDES
64	Pelvic fluid collection	OFFSIDES
65	Pericoronitis	OFFSIDES
66	Peritonitis	OFFSIDES
67	Post procedural complication	OFFSIDES
68	Psychiatric symptom	OFFSIDES
69	Pyelonephritis	OFFSIDES
70	Retinal Vein Occlusion	OFFSIDES
71	Retinal pigment epithelial tear	OFFSIDES
72	Rhabdomyolysis	OFFSIDES
73	Silent myocardial infarction	OFFSIDES
74	Skin lesion	OFFSIDES
75	Spondylitis	OFFSIDES
76	Thrombotic stroke	OFFSIDES
77	Traumatic fracture	OFFSIDES
78	Vitamin K Deficiency	OFFSIDES
79	Weight Gain	OFFSIDES

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