cyclopamine
(QASFUMOKHFSJGL-LAFRSMQTSA-N)
Structure
- SMILES
- O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC2=C(C)[C@]4(CC[C@@H]32)O[C@H]2[C@H]([C@H]4C)NC[C@H](C2)C)C1)C
- Molecular Formula:
- C27H41NO2
- Molecular Weight:
- 411.620
- Log P:
- 5.3307
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 2
- TPSA:
- 41.49
- CAS Number(s):
- 4449-51-8
Synonym(s)
1.
cyclopamine
External Link(s)
| MeSH | C000541 |
| PubChem Compound | 442972 |
| BindingDB | 50232973 |
| ChEBI | 4021 |
| CHEMBL | CHEMBL254129 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 10328 |
| KEGG | cpd:C10798 |
| Therapeutic Target Database | D05UKJ |
| ZINC | 4098868 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abnormalities, Drug-Induced | 17728282 | CTD | |
| 2 | Cleft Palate | 18411234 | CTD | |
| 3 | Craniofacial Abnormalities | 17728282 | CTD | |
| 4 | Edema | 22265815 | CTD | |
| 5 | Holoprosencephaly | 22265815 23264560 | CTD | |
| 6 | Jaw Abnormalities | 16580747 | CTD | |
| 7 | Lung Neoplasms | 22923130 | CTD | |
| 8 | Prenatal Injuries | 22265815 | CTD |
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