Diffuse Large B-Cell Lymphoma
(UMLS:C0079744)
- Definition:
- Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
- UMLS ID:
- C0079744
- MeSH ID:
- N/A
Synonym(s)
1.
Diffuse Large B-Cell Lymphoma
2.
DHL
3.
DHL (diffuse histiocytic lymphoma)
4.
Diffuse large B-cell lymphoma
5.
Diffuse malignant lymphoma - histiocytic
6.
Diffuse malignant lymphoma - large cell
7.
Diffuse non-Hodgkin lymphoma, large cell
8.
Diffuse non-Hodgkin's lymphoma, large cell
9.
Diffuse non-Hodgkin's lymphoma, large cell (clinical)
10.
Large cell (diffuse) non-Hodgkin's lymphoma
11.
Lymphoma, diffuse large B cell, non Hodgkins
12.
Malignant lymphoma - large cell cleaved and non-cleaved
13.
Malignant lymphoma, diffuse, large cell
14.
Malignant lymphoma, histiocytic
15.
Malignant lymphoma, histiocytic, diffuse
16.
Malignant lymphoma, large B-cell
Associated Drug(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Lenalidomide | FAERS: 208 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 2 | Methotrexate | FAERS: 92 | OFFSIDES US FAERS | |
| 3 | Methotrexate | FAERS: 48 | US FAERS | |
| 4 | Mercaptopurine | FAERS: 18 | OFFSIDES US FAERS | |
| 5 | Ruxolitinib phosphate | FAERS: 16 | US FAERS | |
| 6 | Imatinib Mesylate | FAERS: 11 | US FAERS | |
| 7 | Clozapine | FAERS: 10 | OFFSIDES US FAERS | |
| 8 | Tacrolimus | FAERS: 9 | OFFSIDES US FAERS | |
| 9 | pimecrolimus | FAERS: 8 | OFFSIDES US FAERS | |
| 10 | venetoclax | FAERS: 7 | US FAERS | |
| 11 | Fingolimod Hydrochloride | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | PCI 32765 | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | idelalisib | FAERS: 6 | US FAERS | |
| 14 | Temozolomide | FAERS: 5 | OFFSIDES US FAERS | |
| 15 | Alendronate | FAERS: 4 | US FAERS | |
| 16 | Dabigatran | FAERS: 4 | US FAERS | |
| 17 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | FAERS: 3 | US FAERS | |
| 18 | Azacitidine | FAERS: 3 | US FAERS | |
| 19 | Azathioprine | FAERS: 3 | US FAERS | |
| 20 | Dasatinib | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Imatinib Mesylate | FAERS: 3 | US FAERS | |
| 22 | Pentostatin | FAERS: 3 | US FAERS | |
| 23 | Prednisolone | FAERS: 3 | US FAERS | |
| 24 | Sirolimus | FAERS: 3 | OFFSIDES US FAERS | |
| 25 | apremilast | FAERS: 3 | US FAERS | |
| 26 | Bortezomib | FAERS: 2 | US FAERS | |
| 27 | Cladribine | FAERS: 2 | US FAERS | |
| 28 | Cyclosporine | FAERS: 2 | US FAERS | |
| 29 | Emtricitabine, Rilpivirine, Tenofovir Drug Combination | FAERS: 2 | US FAERS | |
| 30 | Leflunomide | FAERS: 2 | OFFSIDES US FAERS | |
| 31 | MDV 3100 | FAERS: 2 | US FAERS | |
| 32 | Prednisone | FAERS: 2 | US FAERS | |
| 33 | Raltegravir Potassium | FAERS: 2 | US FAERS | |
| 34 | Ribavirin | FAERS: 2 | OFFSIDES US FAERS | |
| 35 | Vitamin D | FAERS: 2 | US FAERS | |
| 36 | eltrombopag | FAERS: 2 | US FAERS | |
| 37 | ledipasvir, sofosbuvir drug combination | FAERS: 2 | US FAERS | |
| 38 | pomalidomide | FAERS: 2 | US FAERS | |
| 39 | 4-Aminopyridine | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Acetaminophen | FAERS: 1 | US FAERS | |
| 41 | Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination | FAERS: 1 | US FAERS | |
| 42 | Azithromycin | FAERS: 1 | US FAERS | |
| 43 | Bexarotene | FAERS: 1 | US FAERS | |
| 44 | Chlorambucil | FAERS: 1 | OFFSIDES US FAERS | |
| 45 | Crizotinib | FAERS: 1 | US FAERS | |
| 46 | Daclatasvir dihydrochloride | FAERS: 1 | US FAERS | |
| 47 | Darunavir | FAERS: 1 | OFFSIDES US FAERS | |
| 48 | Deferasirox | FAERS: 1 | US FAERS | |
| 49 | Dronedarone | FAERS: 1 | US FAERS | |
| 50 | Epoprostenol | FAERS: 1 | US FAERS | |
| 51 | Erlotinib Hydrochloride | FAERS: 1 | US FAERS | |
| 52 | Estramustine phosphate | FAERS: 1 | US FAERS | |
| 53 | Fluoxetine | FAERS: 1 | US FAERS | |
| 54 | GS-7340 | FAERS: 1 | US FAERS | |
| 55 | Hydroxyurea | FAERS: 1 | US FAERS | |
| 56 | Ibandronic Acid | FAERS: 1 | US FAERS | |
| 57 | Liraglutide | FAERS: 1 | US FAERS | |
| 58 | Melphalan | FAERS: 1 | US FAERS | |
| 59 | Metformin | FAERS: 1 | US FAERS | |
| 60 | Methylprednisolone | FAERS: 1 | US FAERS | |
| 61 | Mycophenolic Acid | FAERS: 1 | US FAERS | |
| 62 | Mycophenolic Acid | FAERS: 1 | US FAERS | |
| 63 | Omeprazole | FAERS: 1 | US FAERS | |
| 64 | Procarbazine | FAERS: 1 | US FAERS | |
| 65 | Tamoxifen | FAERS: 1 | US FAERS | |
| 66 | Tenofovir | FAERS: 1 | OFFSIDES US FAERS | |
| 67 | Teriparatide | FAERS: 1 | US FAERS | |
| 68 | Thalidomide | FAERS: 1 | US FAERS | |
| 69 | Thyroxine | FAERS: 1 | US FAERS | |
| 70 | Valganciclovir | FAERS: 1 | US FAERS | |
| 71 | Valsartan | FAERS: 1 | US FAERS | |
| 72 | Zoledronic Acid | FAERS: 1 | US FAERS | |
| 73 | empagliflozin | FAERS: 1 | US FAERS | |
| 74 | macitentan | FAERS: 1 | US FAERS | |
| 75 | midostaurin | FAERS: 1 | US FAERS | |
| 76 | pirfenidone | FAERS: 1 | US FAERS | |
| 77 | sofosbuvir-velpatasvir drug combination | FAERS: 1 | US FAERS | |
| 78 | teriflunomide | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 79 | tofacitinib | FAERS: 1 | US FAERS | |
| 80 | Acarbose | OFFSIDES | ||
| 81 | Acyclovir | OFFSIDES | ||
| 82 | Amlodipine | OFFSIDES | ||
| 83 | Anastrozole | OFFSIDES | ||
| 84 | Calcitriol | OFFSIDES | ||
| 85 | Cefoxitin | OFFSIDES | ||
| 86 | Chondroitin Sulfates | OFFSIDES | ||
| 87 | Cysteamine | SIDER | ||
| 88 | Cytarabine | SIDER | ||
| 89 | Dacarbazine | OFFSIDES | ||
| 90 | Doxorubicin | OFFSIDES | ||
| 91 | Dronabinol | OFFSIDES | ||
| 92 | Etoposide | OFFSIDES | ||
| 93 | Felbinac | OFFSIDES | ||
| 94 | Isoniazid | OFFSIDES | ||
| 95 | Leucovorin | OFFSIDES | ||
| 96 | Maraviroc | SIDER | ||
| 97 | Meropenem | OFFSIDES | ||
| 98 | Mesna | OFFSIDES | ||
| 99 | Methyltestosterone | OFFSIDES | ||
| 100 | Metoprolol | OFFSIDES | ||
| 101 | Mometasone Furoate | OFFSIDES | ||
| 102 | Nabumetone | OFFSIDES | ||
| 103 | Nateglinide | OFFSIDES | ||
| 104 | Penicillin V | OFFSIDES | ||
| 105 | Primidone | OFFSIDES | ||
| 106 | Pyridostigmine Bromide | OFFSIDES | ||
| 107 | Pyridoxal Phosphate | OFFSIDES | ||
| 108 | Rabeprazole | OFFSIDES | ||
| 109 | Risedronic Acid | OFFSIDES | ||
| 110 | Ritonavir | OFFSIDES | ||
| 111 | Stavudine | OFFSIDES | ||
| 112 | Sulfasalazine | OFFSIDES | ||
| 113 | Sumatriptan | OFFSIDES | ||
| 114 | Tamsulosin | OFFSIDES | ||
| 115 | Vinblastine | OFFSIDES | ||
| 116 | Vincristine | OFFSIDES | ||
| 117 | Vitamin K 2 | OFFSIDES | ||
| 118 | aceclofenac | OFFSIDES | ||
| 119 | arotinolol | OFFSIDES | ||
| 120 | fludarabine phosphate | OFFSIDES | ||
| 121 | fludarabine | OFFSIDES | ||
| 122 | mebeverine | OFFSIDES | ||
| 123 | mizoribine | OFFSIDES |
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