MetaADEDB 2.0 @ LMMD
arotinolol
(BHIAIPWSVYSKJS-UHFFFAOYSA-N)
Structure
SMILES
OC(CSc1scc(n1)c1ccc(s1)C(=O)N)CNC(C)(C)C
Type(s)
Investigational
Molecular Formula:
C15H21N3O2S3
Molecular Weight:
371.541
Log P:
3.9028
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
3
TPSA:
170.02
CAS Number(s):
52560-77-7; 68377-92-4
Synonym(s)
1.
arotinolol
2.
2-(3'-tert-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-thienyl)thiazole hydrochloride
3.
S 596
4.
S-596
5.
arotinolol hydrochloride
6.
arotinolol, (+-)-isomer
External Link(s)
MeSHC024523
PubChem Compound2239
BindingDB81885
ChEBI135569
CHEMBLCHEMBL93298
DrugBankDB09204
DrugCentral243
KEGGdr:D07465
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AbasiaOFFSIDES
2AmphetaminesOFFSIDES
3Anticonvulsant drug level increasedOFFSIDES
4AsthmaOFFSIDES
5AtelectasisOFFSIDES
6Atrioventricular BlockOFFSIDES
7AuraOFFSIDES
8Blood GlucoseOFFSIDES
9Blood amylase increasedOFFSIDES
10Blood creatine phosphokinase increasedOFFSIDES
11Blood glucose decreasedOFFSIDES
12BradycardiaOFFSIDES
13BronchopneumoniaOFFSIDES
14Bulbar palsyOFFSIDES
15Cardiac TamponadeOFFSIDES
16Cardiovascular insufficiencyOFFSIDES
17CholangiolitisOFFSIDES
18ChromaturiaOFFSIDES
19Depressed Level of ConsciousnessOFFSIDES
20DiarrheaOFFSIDES
21Diffuse Large B-Cell LymphomaOFFSIDES
22Disseminated Intravascular CoagulationOFFSIDES
23Febrile NeutropeniaOFFSIDES
24GangreneOFFSIDES
25Hepatic congestionOFFSIDES
26HepatitisOFFSIDES
27HyperreflexiaOFFSIDES
28Intestinal ObstructionOFFSIDES
29Markedly reduced dietary intakeOFFSIDES
30Metabolic acidosisOFFSIDES
31Musculoskeletal PainOFFSIDES
32NephrolithiasisOFFSIDES
33Neuroleptic Malignant SyndromeOFFSIDES
34NystagmusOFFSIDES
35Oculomucocutaneous syndromeOFFSIDES
36Phrenic nerve paralysisOFFSIDES
37Renal cystOFFSIDES
38Renal tubular disorderOFFSIDES
39Respiratory FailureOFFSIDES
40RhabdomyolysisOFFSIDES
41Small intestine carcinomaOFFSIDES
42Sudden onset of sleepOFFSIDES
43Tachycardia29117
2575990		CTD
44Unresponsive to stimuliOFFSIDES
45Ventricular FibrillationOFFSIDES
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