MetaADEDB 2.0 @ LMMD
mebeverine
(VYVKHNNGDFVQGA-UHFFFAOYSA-N)
Structure
SMILES
COc1ccc(cc1)CC(N(CCCCOC(=O)c1ccc(c(c1)OC)OC)CC)C
Type(s)
Approved; Investigational
ATC code(s)
A03AA04
Molecular Formula:
C25H35NO5
Molecular Weight:
429.549
Log P:
4.6025
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
0
TPSA:
57.23
CAS Number(s):
3625-06-7; 630203
Synonym(s)
1.
mebeverine
2.
4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate
3.
duspatalin
4.
mebeverine hydrochloride
5.
spasmotalin
External Link(s)
MeSHC005096
PubChem Compound4031
ChEBI91514
CHEMBLCHEMBL282121
DrugBankDB12554
DrugCentral1642
IUPHAR/BPS Guide to PHARMACOLOGY9011
KEGGdr:D08160
Therapeutic Target DatabaseD0VU8Q
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainOFFSIDES
2Abnormal visionOFFSIDES
3Accidental overdoseOFFSIDES
4Acute Coronary SyndromeOFFSIDES
5Acute myocardial infarctionOFFSIDES
6AgoraphobiaOFFSIDES
7AgraphiaOFFSIDES
8AmnesiaOFFSIDES
9Anal abscessOFFSIDES
10Anaphylactic shockSIDER
11AneurysmOFFSIDES
12AngerOFFSIDES
13AngioedemaSIDER
14AnorexiaSIDER
15AnosmiaOFFSIDES
16Antidepressant drug level increasedOFFSIDES
17Aortic AneurysmOFFSIDES
18AtelectasisOFFSIDES
19Bipolar I disorderOFFSIDES
20Blood alkaline phosphatase increasedOFFSIDES
21Blood fibrinogenOFFSIDES
22Blood sodiumOFFSIDES
23Blurred visionOFFSIDES
24Bowen's DiseaseOFFSIDES
25Brain scan abnormalOFFSIDES
26Cardiac TamponadeOFFSIDES
27Cardiac perforationOFFSIDES
28Cell DeathOFFSIDES
29Chemotherapeutic drug level increasedOFFSIDES
30Choking sensationOFFSIDES
31ChokingOFFSIDES
32CholangiolitisOFFSIDES
33ChromatopsiaOFFSIDES
34ClaustrophobiaOFFSIDES
35ConfabulationOFFSIDES
36Conjunctival erosionOFFSIDES
37Conjunctival ulcerOFFSIDES
38Depressed moodOFFSIDES
39DermatitisSIDER
40DiarrheaOFFSIDES
41Diffuse Large B-Cell LymphomaOFFSIDES
42DiscomfortSIDER
43DizzinessSIDER
44Drug dispensing errorOFFSIDES
45DyspepsiaOFFSIDES
SIDER
46Dysthymic DisorderOFFSIDES
47DysuriaOFFSIDES
48EczemaOFFSIDES
49Electrocardiogram changeOFFSIDES
50Electromechanical dissociationOFFSIDES
51Emotional disorderOFFSIDES
52EpistaxisOFFSIDES
53Erectile dysfunctionOFFSIDES
54Erosive gastritisOFFSIDES
55Feeling abnormalSIDER
56FormicationOFFSIDES
57FrustrationOFFSIDES
58Gamma-Glutamyltransferase IncreasedOFFSIDES
59Glasgow coma scaleOFFSIDES
60HaematotoxicityOFFSIDES
61HeadacheSIDER
62HeartburnSIDER
63HyperreflexiaOFFSIDES
64HypersensitivitySIDER
65IncontinenceOFFSIDES
66Infusion site mobility decreasedOFFSIDES
67Intention tremorOFFSIDES
68Intentional self-injuryOFFSIDES
69Intermittent ClaudicationOFFSIDES
70Intestinal ObstructionOFFSIDES
71IritisOFFSIDES
72Kidney NeoplasmOFFSIDES
73LethargyOFFSIDES
74LeukoencephalopathyOFFSIDES
75Leukopenia neonatalOFFSIDES
76MalaiseSIDER
77MonoparesisOFFSIDES
78Mucosal erosionOFFSIDES
79Musculoskeletal chest painOFFSIDES
80Negative thoughtsOFFSIDES
81Nervous tensionOFFSIDES
82Neutropenic sepsisOFFSIDES
83NystagmusOFFSIDES
84Oropharyngeal blisteringOFFSIDES
85PallorOFFSIDES
86ParanoiaOFFSIDES
87Pelvic abscessOFFSIDES
88PolyuriaOFFSIDES
89Poor quality sleepOFFSIDES
90Pulmonary HypertensionOFFSIDES
91RhabdomyolysisOFFSIDES
92RhinitisOFFSIDES
93Sinus bradycardiaOFFSIDES
94Therapy non-responderOFFSIDES
95UrticariaSIDER
96Venous thrombosis limbOFFSIDES
97Visual disturbanceOFFSIDES
98VulvitisOFFSIDES
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