Ototoxicity
(UMLS:C0235280)
- Definition:
- Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
- UMLS ID:
- C0235280
- MeSH ID:
- N/A
Synonym(s)
1.
Ototoxicity
2.
OTOTOXICITY
3.
Ototoxicity, NOS
4.
ototoxicity
Associated Drug(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Gentamicins | FAERS: 30 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 2 | Erythromycin | FAERS: 24 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 3 | Clarithromycin | FAERS: 14 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 4 | Deferoxamine | FAERS: 8 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 5 | Tobramycin | FAERS: 8 | OFFSIDES SIDER US FAERS | |
| 6 | Gabapentin | FAERS: 6 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 7 | Hydroxychloroquine | FAERS: 5 | US FAERS | |
| 8 | Erythromycin Ethylsuccinate | FAERS: 4 | US FAERS | |
| 9 | Furosemide | FAERS: 4 | SIDER US FAERS | |
| 10 | Metronidazole | FAERS: 4 | US FAERS | |
| 11 | Naproxen | FAERS: 4 | US FAERS | |
| 12 | erythromycin stearate | FAERS: 4 | US FAERS | |
| 13 | Amikacin | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance SIDER US FAERS | |
| 14 | Aprotinin | FAERS: 3 | US FAERS | |
| 15 | Bortezomib | FAERS: 3 | US FAERS | |
| 16 | Cephalexin | FAERS: 3 | US FAERS | |
| 17 | Ciprofloxacin | FAERS: 3 | US FAERS | |
| 18 | Linezolid | FAERS: 3 | OFFSIDES US FAERS | |
| 19 | Vancomycin | FAERS: 3 | US FAERS | |
| 20 | Aspirin | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Atenolol | FAERS: 2 | US FAERS | |
| 22 | Carboplatin | FAERS: 2 | SIDER US FAERS | |
| 23 | Erlotinib Hydrochloride | FAERS: 2 | US FAERS | |
| 24 | Minocycline | FAERS: 2 | US FAERS | |
| 25 | Paclitaxel | FAERS: 2 | SIDER US FAERS | |
| 26 | Tamoxifen | FAERS: 2 | US FAERS | |
| 27 | bedaquiline | FAERS: 2 | US FAERS | |
| 28 | erythromycin propionate | FAERS: 2 | US FAERS | |
| 29 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | FAERS: 1 | US FAERS | |
| 30 | Amlodipine | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 31 | Avalide | FAERS: 1 | US FAERS | |
| 32 | Azithromycin | FAERS: 1 | US FAERS | |
| 33 | Bumetanide | FAERS: 1 | US FAERS | |
| 34 | Ceftriaxone | FAERS: 1 | US FAERS | |
| 35 | Cetirizine | FAERS: 1 | US FAERS | |
| 36 | Chlorhexidine | FAERS: 1 | US FAERS | |
| 37 | Chloroquine | FAERS: 1 | OFFSIDES US FAERS | |
| 38 | Cyclosporine | FAERS: 1 | US FAERS | |
| 39 | Dabigatran | FAERS: 1 | US FAERS | |
| 40 | Deferasirox | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 41 | Deferoxamine | FAERS: 1 | OFFSIDES US FAERS | |
| 42 | Duloxetine Hydrochloride | FAERS: 1 | US FAERS | |
| 43 | Epirubicin | FAERS: 1 | US FAERS | |
| 44 | Erlotinib Hydrochloride | FAERS: 1 | US FAERS | |
| 45 | Ethacrynic Acid | FAERS: 1 | US FAERS | |
| 46 | Fluorouracil | FAERS: 1 | US FAERS | |
| 47 | Hydroxychloroquine | FAERS: 1 | US FAERS | |
| 48 | Ibuprofen | FAERS: 1 | US FAERS | |
| 49 | Iloprost | FAERS: 1 | US FAERS | |
| 50 | Isotretinoin | FAERS: 1 | US FAERS | |
| 51 | Itraconazole | FAERS: 1 | US FAERS | |
| 52 | Letrozole | FAERS: 1 | US FAERS | |
| 53 | Levofloxacin | FAERS: 1 | US FAERS | |
| 54 | Lisdexamfetamine Dimesylate | FAERS: 1 | US FAERS | |
| 55 | Lorcet | FAERS: 1 | US FAERS | |
| 56 | Melphalan | FAERS: 1 | US FAERS | |
| 57 | Methotrexate | FAERS: 1 | US FAERS | |
| 58 | Minocycline | FAERS: 1 | US FAERS | |
| 59 | Omeprazole | FAERS: 1 | US FAERS | |
| 60 | Oxytocin | FAERS: 1 | US FAERS | |
| 61 | Paroxetine | FAERS: 1 | US FAERS | |
| 62 | Pregabalin | FAERS: 1 | US FAERS | |
| 63 | Prezcobix | FAERS: 1 | US FAERS | |
| 64 | Rifampin | FAERS: 1 | OFFSIDES US FAERS | |
| 65 | Sertraline | FAERS: 1 | US FAERS | |
| 66 | Sertraline | FAERS: 1 | OFFSIDES US FAERS | |
| 67 | Sunitinib | FAERS: 1 | US FAERS | |
| 68 | Tadalafil | FAERS: 1 | US FAERS | |
| 69 | Tenofovir | FAERS: 1 | US FAERS | |
| 70 | Thalidomide | FAERS: 1 | US FAERS | |
| 71 | Torsemide | FAERS: 1 | US FAERS | |
| 72 | Tramadol | FAERS: 1 | US FAERS | |
| 73 | Vancomycin | FAERS: 1 | US FAERS | |
| 74 | Varenicline | FAERS: 1 | US FAERS | |
| 75 | aliskiren | FAERS: 1 | US FAERS | |
| 76 | atovaquone, proguanil drug combination | FAERS: 1 | US FAERS | |
| 77 | chloroquine diphosphate | FAERS: 1 | US FAERS | |
| 78 | elbasvir-grazoprevir drug combination | FAERS: 1 | US FAERS | |
| 79 | exemestane | FAERS: 1 | US FAERS | |
| 80 | gemcitabine | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 81 | halofantrine | FAERS: 1 | US FAERS | |
| 82 | liposomal amphotericin B | FAERS: 1 | US FAERS | |
| 83 | pazopanib | FAERS: 1 | US FAERS | |
| 84 | pomalidomide | FAERS: 1 | US FAERS | |
| 85 | Acebutolol | OFFSIDES | ||
| 86 | Amifostine | OFFSIDES | ||
| 87 | Amikacin | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Buprenorphine | OFFSIDES | ||
| 89 | Cetirizine | SIDER | ||
| 90 | Clopidogrel | OFFSIDES | ||
| 91 | Dactinomycin | OFFSIDES | ||
| 92 | Docetaxel | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 93 | Ethambutol | OFFSIDES | ||
| 94 | Etoposide | OFFSIDES | ||
| 95 | Floxacillin | OFFSIDES | ||
| 96 | Hydrocortisone | OFFSIDES | ||
| 97 | Ifosfamide | OFFSIDES | ||
| 98 | Ivermectin | OFFSIDES | ||
| 99 | Kanamycin | SIDER | ||
| 100 | Lapatinib | OFFSIDES | ||
| 101 | Mefloquine | OFFSIDES | ||
| 102 | Mesna | OFFSIDES | ||
| 103 | Neomycin | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 104 | Norepinephrine | OFFSIDES | ||
| 105 | Palonosetron | OFFSIDES | ||
| 106 | Pemetrexed | OFFSIDES | ||
| 107 | Phenylbutazone | Canada Vigilance: 1 | Canada Vigilance | |
| 108 | Ribavirin | OFFSIDES | ||
| 109 | Rosiglitazone | Canada Vigilance: 1 | Canada Vigilance | |
| 110 | Sitagliptin Phosphate | OFFSIDES | ||
| 111 | Sodium | SIDER | ||
| 112 | Streptomycin | SIDER | ||
| 113 | Thiotepa | SIDER | ||
| 114 | Tramadol | Canada Vigilance: 1 | Canada Vigilance | |
| 115 | Vancomycin | SIDER | ||
| 116 | Vinorelbine | SIDER | ||
| 117 | amphotericin B, deoxycholate drug combination | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | gemcitabine | OFFSIDES |
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