amphotericin B, deoxycholate drug combination
(NFHDUMMQBQTVTR-OXEBIIQQSA-M)
Structure
- SMILES
- O[C@@H]1CC[C@@H](O)[C@H](O)C[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@@H](O2)C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H]([C@H]([C@H]([C@@H](OC(=O)C[C@@H](C1)O)C)C)O)C)O[C@@H]1O[C@H](C)[C@H]([C@@H]([C@@H]1O)N)O)C(=O)O.O[C@@H]1CC[C@]2([C@@H](C1)CC[C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)[O-])C)C)C.[Na+]
- Molecular Formula:
- C71H112NNaO21
- Molecular Weight:
- 1338.630
- Log P:
- 4.5552
- Hydrogen Bond Acceptor:
- 22
- Hydrogen Bond Donor:
- 14
- TPSA:
- 400.2
- CAS Number(s):
- N/A
Synonym(s)
1.
amphotericin B, deoxycholate drug combination
2.
D-AmB cpd
3.
HAmB-DOC
4.
amphotericin B - deoxycholate
5.
amphotericin B deoxycholate
6.
amphotericin B-deoxycholate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | AIDS-Related Opportunistic Infections | 20536366 | CTD | |
| 2 | Acute kidney injury | Canada Vigilance: 1 | CTD Canada Vigilance | |
| 3 | Agitation | Canada Vigilance: 1 | Canada Vigilance | |
| 4 | Chemical and Drug Induced Liver Injury | 10965993 | CTD | |
| 5 | Chills | Canada Vigilance: 5 | 17718252 | CTD Canada Vigilance |
| 6 | Cyanosis | Canada Vigilance: 2 | Canada Vigilance | |
| 7 | Erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 8 | Fever | 20140311 | CTD | |
| 9 | Hypokalemia | CTD | ||
| 10 | Inflammation | 10965993 | CTD | |
| 11 | Kidney Diseases | CTD | ||
| 12 | Leishmaniasis, Visceral | 10897369 11035738 | CTD | |
| 13 | Lung Diseases, Interstitial | 10965993 | CTD | |
| 14 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 15 | Meningitis, Cryptococcal | 20536366 | CTD | |
| 16 | Mycoses | 11322173 20140311 | CTD | |
| 17 | Nausea | Canada Vigilance: 2 | Canada Vigilance | |
| 18 | Necrosis | 22863853 | CTD | |
| 19 | Ototoxicity | Canada Vigilance: 1 | Canada Vigilance | |
| 20 | Thrombocytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Tremor | Canada Vigilance: 1 | Canada Vigilance | |
| 22 | Vomiting | Canada Vigilance: 1 | Canada Vigilance |
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