MetaADEDB 2.0 @ LMMD
Avalide
(NZPSYYOURGWZCM-UHFFFAOYSA-N)
Structure
SMILES
Clc1cc2NCNS(=O)(=O)c2cc1S(=O)(=O)N.CCCCC1=NC2(C(=O)N1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CCCC2
Molecular Formula:
C32H36ClN9O5S2
Molecular Weight:
726.269
Log P:
7.1283
Hydrogen Bond Acceptor:
13
Hydrogen Bond Donor:
4
TPSA:
222.25
CAS Number(s):
448264-66-2
Synonym(s)
1.
Avalide
External Link(s)
PubChem Compound9831761
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 53
Canada Vigilance: 3
Canada Vigilance
US FAERS
2DizzinessFAERS: 47SIDER
US FAERS
3HeadacheFAERS: 32
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
4Product contamination microbialFAERS: 28US FAERS
5DysgeusiaFAERS: 24
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
6Medication ErrorFAERS: 21US FAERS
7MalaiseFAERS: 17SIDER
US FAERS
8NauseaFAERS: 16SIDER
US FAERS
9Adverse eventFAERS: 13US FAERS
10FatigueFAERS: 13
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
11HypotensionFAERS: 13SIDER
US FAERS
12PalpitationsFAERS: 12US FAERS
13AstheniaFAERS: 11SIDER
US FAERS
14Back PainFAERS: 11US FAERS
15Blood pressure fluctuationFAERS: 10US FAERS
16Blood pressure inadequately controlledFAERS: 10US FAERS
17Erectile dysfunctionFAERS: 10US FAERS
18Product quality issueFAERS: 10US FAERS
19TinnitusFAERS: 10SIDER
US FAERS
20Drug dose omissionFAERS: 9US FAERS
21MyalgiaFAERS: 9
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
22PainFAERS: 9
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
23AlopeciaFAERS: 8US FAERS
24HypersensitivityFAERS: 7SIDER
US FAERS
25PruritusFAERS: 7SIDER
US FAERS
26UrticariaFAERS: 7SIDER
US FAERS
27Abdominal discomfortFAERS: 6US FAERS
28AngioedemaFAERS: 6SIDER
US FAERS
29Feeling abnormalFAERS: 6SIDER
US FAERS
30Joint swellingFAERS: 6US FAERS
31SwellingFAERS: 6US FAERS
32VomitingFAERS: 6SIDER
US FAERS
33AnxietyFAERS: 5SIDER
US FAERS
34Blood potassium decreasedFAERS: 5US FAERS
35Chest PainFAERS: 5SIDER
US FAERS
36Circumstance or information capable of leading to medication errorFAERS: 5US FAERS
37FlushingFAERS: 5SIDER
US FAERS
38GoutFAERS: 5SIDER
US FAERS
39Musculoskeletal PainFAERS: 5US FAERS
40TachycardiaFAERS: 5SIDER
US FAERS
41TremorFAERS: 5SIDER
US FAERS
42Wrong technique in product usage processFAERS: 5US FAERS
43Abdominal PainFAERS: 4
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
44ArthropathyFAERS: 4US FAERS
45Blood creatinine increasedFAERS: 4US FAERS
46Blood glucose increasedFAERS: 4US FAERS
47Blood potassium increasedFAERS: 4US FAERS
48Diabetes MellitusFAERS: 4SIDER
US FAERS
49DyspepsiaFAERS: 4SIDER
US FAERS
50FlatulenceFAERS: 4SIDER
US FAERS
51No adverse eventFAERS: 4US FAERS
52PregnancyFAERS: 4US FAERS
53SyncopeFAERS: 4SIDER
US FAERS
54VertigoFAERS: 4SIDER
US FAERS
55Visual ImpairmentFAERS: 4SIDER
US FAERS
56Apparent deathFAERS: 3US FAERS
57AsthmaFAERS: 3US FAERS
58Blood sodium decreasedFAERS: 3US FAERS
59ChillsFAERS: 3US FAERS
60ConstipationFAERS: 3SIDER
US FAERS
61DeafnessFAERS: 3US FAERS
62Drug dispensing errorFAERS: 3US FAERS
63Hypertensive crisisFAERS: 3US FAERS
64Incorrect dose administeredFAERS: 3US FAERS
65NephrolithiasisFAERS: 3US FAERS
66NervousnessFAERS: 3SIDER
US FAERS
67NocturiaFAERS: 3US FAERS
68OverdoseFAERS: 3US FAERS
69ShockFAERS: 3SIDER
US FAERS
70SomnolenceFAERS: 3SIDER
US FAERS
71Unevaluable eventFAERS: 3US FAERS
72AgeusiaFAERS: 2US FAERS
73ArthralgiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
74Atrial FibrillationFAERS: 2US FAERS
75Basal cell carcinomaFAERS: 2US FAERS
76Blood creatine phosphokinase increasedFAERS: 2US FAERS
77Cerebrovascular accidentFAERS: 2US FAERS
78CystFAERS: 2US FAERS
79Depressed moodFAERS: 2US FAERS
80DisorientationFAERS: 2US FAERS
81Dry skinFAERS: 2US FAERS
82DysuriaFAERS: 2US FAERS
83Electrolyte imbalanceFAERS: 2SIDER
US FAERS
84EpistaxisFAERS: 2SIDER
US FAERS
85ErythemaFAERS: 2SIDER
US FAERS
86Flank PainFAERS: 2US FAERS
87InfluenzaFAERS: 2SIDER
US FAERS
88Muscle CrampFAERS: 2US FAERS
89Muscle tightnessFAERS: 2US FAERS
90NasopharyngitisFAERS: 2US FAERS
91Night sweatsFAERS: 2US FAERS
92Olfactory Nerve DisorderFAERS: 2US FAERS
93Pharmaceutical product complaintFAERS: 2US FAERS
94PolyuriaFAERS: 2US FAERS
95Product counterfeitFAERS: 2US FAERS
96Product substitution issueFAERS: 2US FAERS
97Renal painFAERS: 2US FAERS
98Respiratory arrestFAERS: 2US FAERS
99RhabdomyolysisFAERS: 2SIDER
US FAERS
100Therapeutic response unexpectedFAERS: 2US FAERS
101Throat irritationFAERS: 2US FAERS
102Transaminases increasedFAERS: 2US FAERS
103Weight decreasedFAERS: 2US FAERS
104AbasiaFAERS: 1US FAERS
105Accidental drug intake by childFAERS: 1US FAERS
106Accidental overdoseFAERS: 1US FAERS
107Actinic keratosisFAERS: 1US FAERS
108AgitationFAERS: 1SIDER
US FAERS
109Anaphylactic shockFAERS: 1SIDER
US FAERS
110AneurysmFAERS: 1US FAERS
111Angle Closure GlaucomaFAERS: 1US FAERS
112Aortic AneurysmFAERS: 1US FAERS
113ArthritisFAERS: 1SIDER
US FAERS
114AtopyFAERS: 1US FAERS
115Benign Prostatic HyperplasiaFAERS: 1US FAERS
116Bladder spasmFAERS: 1US FAERS
117Blood cholesterol increasedFAERS: 1US FAERS
118Blood electrolytes decreasedFAERS: 1US FAERS
119Blood electrolytes increasedFAERS: 1US FAERS
120Blood potassium abnormalFAERS: 1US FAERS
121Blood sodium abnormalFAERS: 1US FAERS
122Blood triglycerides increasedFAERS: 1US FAERS
123Blood urea increasedFAERS: 1US FAERS
124Blood urine presentFAERS: 1US FAERS
125Bone painFAERS: 1SIDER
US FAERS
126BronchitisFAERS: 1US FAERS
127Burning sensationFAERS: 1US FAERS
128BursitisFAERS: 1US FAERS
129Capillary Leak SyndromeFAERS: 1US FAERS
130Cardiac ArrestFAERS: 1US FAERS
131Carpal Tunnel SyndromeFAERS: 1US FAERS
132Chest discomfortFAERS: 1US FAERS
133Cold sweatFAERS: 1US FAERS
134Counterfeit drug administeredFAERS: 1US FAERS
135CryingFAERS: 1US FAERS
136DehydrationFAERS: 1US FAERS
137DementiaFAERS: 1US FAERS
138Diabetes mellitus inadequate controlFAERS: 1US FAERS
139DisabilityFAERS: 1US FAERS
140Disease complicationFAERS: 1US FAERS
141Drug abuseFAERS: 1US FAERS
142Drug administration errorFAERS: 1US FAERS
143Duodenal UlcerFAERS: 1US FAERS
144DysarthriaFAERS: 1US FAERS
145DysphoniaFAERS: 1US FAERS
146Ear discomfortFAERS: 1US FAERS
147EczemaFAERS: 1US FAERS
148Electrocardiogram repolarisation abnormalityFAERS: 1US FAERS
149Emotional disorderFAERS: 1US FAERS
150EructationFAERS: 1US FAERS
151Erythema MultiformeFAERS: 1US FAERS
152Expired drug administeredFAERS: 1US FAERS
153Feeling jitteryFAERS: 1US FAERS
154FibromyalgiaFAERS: 1US FAERS
155Foreign body traumaFAERS: 1US FAERS
156GastritisFAERS: 1US FAERS
157HypothyroidismFAERS: 1US FAERS
158IleusFAERS: 1US FAERS
159Impaired work abilityFAERS: 1US FAERS
160Incorrect product storageFAERS: 1US FAERS
161Increased viscosity of upper respiratory secretionFAERS: 1US FAERS
162InfectionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
163Infrequent bowel movementsFAERS: 1US FAERS
164Intentional product misuseFAERS: 1US FAERS
165Intestinal ObstructionFAERS: 1US FAERS
166Intraocular pressure fluctuationFAERS: 1US FAERS
167Joint injuryFAERS: 1US FAERS
168KeratitisFAERS: 1US FAERS
169Labile blood pressureFAERS: 1US FAERS
170LacerationFAERS: 1US FAERS
171LethargyFAERS: 1US FAERS
172Lichen PlanusFAERS: 1US FAERS
173Limb operationFAERS: 1US FAERS
174Lip swellingFAERS: 1US FAERS
175LipomaFAERS: 1US FAERS
176Lupus-like syndromeFAERS: 1US FAERS
177LymphadenopathyFAERS: 1US FAERS
178MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
179Memory impairmentFAERS: 1US FAERS
180Meniscus injuryFAERS: 1US FAERS
181Migraine with AuraFAERS: 1US FAERS
182Musculoskeletal discomfortFAERS: 1SIDER
US FAERS
183Musculoskeletal stiffnessFAERS: 1SIDER
US FAERS
184MydriasisFAERS: 1US FAERS
185Myocardial InfarctionFAERS: 1SIDER
US FAERS
186Neck PainFAERS: 1US FAERS
187Oropharyngeal swellingFAERS: 1US FAERS
188OsteoporosisFAERS: 1US FAERS
189OtotoxicityFAERS: 1US FAERS
190PancreatitisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
191Pelvic PainFAERS: 1US FAERS
192PharyngotonsillitisFAERS: 1US FAERS
193PneumoniaFAERS: 1SIDER
US FAERS
194PolymyositisFAERS: 1US FAERS
195Product comminglingFAERS: 1US FAERS
196Product dose omissionFAERS: 1US FAERS
197Product formulation issueFAERS: 1US FAERS
198Product packaging issueFAERS: 1US FAERS
199Product size issueFAERS: 1US FAERS
200Product taste abnormalFAERS: 1US FAERS
201Product use issueFAERS: 1US FAERS
202ProteinuriaFAERS: 1US FAERS
203PsoriasisFAERS: 1US FAERS
204Pulmonary EmbolismFAERS: 1US FAERS
205Pulmonary HypertensionFAERS: 1US FAERS
206Respiratory tract congestionFAERS: 1US FAERS
207RetchingFAERS: 1US FAERS
208Retinal DegenerationFAERS: 1US FAERS
209Retinal DetachmentFAERS: 1US FAERS
210Retinal artery embolismFAERS: 1US FAERS
211Rheumatoid ArthritisFAERS: 1US FAERS
212ScabFAERS: 1US FAERS
213Stevens-Johnson SyndromeFAERS: 1US FAERS
214Tablet physical issueFAERS: 1US FAERS
215Temperature intoleranceFAERS: 1US FAERS
216Urinary RetentionFAERS: 1US FAERS
217Urinary tract infectionFAERS: 1US FAERS
218Uterine CancerFAERS: 1US FAERS
219White blood cell count decreasedFAERS: 1US FAERS
220Wrong drug administeredFAERS: 1US FAERS
221Wrong technique in drug usage processFAERS: 1US FAERS
222Acute Coronary SyndromeSIDER
223AgranulocytosisSIDER
224Angina PectorisCanada Vigilance: 1Canada Vigilance
225AnorexiaSIDER
226Atrial rhythmSIDER
227BradycardiaSIDER
228Coordination disturbanceSIDER
229DermatitisSIDER
230DiscomfortSIDER
231Epigastric discomfortSIDER
232Epigastric painSIDER
233Feeling ColdSIDER
234Gastric irritationSIDER
235Gastrointestinal PainSIDER
236GlycosuriaSIDER
237HeartburnSIDER
238HepatitisSIDER
239LeukopeniaSIDER
240MetastasisCanada Vigilance: 1Canada Vigilance
241MonoparesisSIDER
242Mood swingsSIDER
243NeutropeniaSIDER
244NumbnessSIDER
245Oral lesionSIDER
246PharyngitisSIDER
247Respiratory distressSIDER
248RhinitisSIDER
249Sensation of warmthSIDER
250Sexual DysfunctionSIDER
251Skin discomfortSIDER
252StiffnessSIDER
253StressSIDER
254Swelling of limbSIDER
255TensionSIDER
256ThrombocytopeniaSIDER
257Toxic Epidermal NecrolysisSIDER
258TraumaSIDER
259VasculitisSIDER
260Ventricular arrhythmiaSIDER
261WheezingSIDER
262XanthopsiaSIDER
263bad tasteSIDER
264jaundiceSIDER
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