MetaADEDB 2.0 @ LMMD
halofantrine
(FOHHNHSLJDZUGQ-UHFFFAOYSA-N)
Structure
SMILES
CCCCN(CCC(c1cc2c(Cl)cc(cc2c2c1ccc(c2)C(F)(F)F)Cl)O)CCCC
Type(s)
Approved
ATC code(s)
P01BX01
Molecular Formula:
C26H30Cl2F3NO
Molecular Weight:
500.424
Log P:
8.6443
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
23.47
CAS Number(s):
66051-76-1; 69756-53-2
Synonym(s)
1.
halofantrine
2.
1-(1,3-dichloro-6-trifluoromethyl-9-phenanthryl)-3-di(n-butyl)aminopropanol HCl
3.
Halfan
4.
WR 171,699
5.
WR 171669
6.
WR-171,669
7.
WR-171699
8.
halofantrine hydrochloride
External Link(s)
MeSHC023768
PubChem Compound37393
BindingDB79214
50096846
ChEBI94392
CHEMBLCHEMBL1107
DrugBankDB01218
DrugCentral1350
IUPHAR/BPS Guide to PHARMACOLOGY10019
KEGGcpd:C07634
dr:D08033
Therapeutic Target DatabaseD07MVK
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood urine presentFAERS: 2US FAERS
2ChromaturiaFAERS: 2US FAERS
3MalaiseFAERS: 2SIDER
US FAERS
4PallorFAERS: 1US FAERS
5Plasmodium falciparum infectionFAERS: 1US FAERS
6Abdominal PainSIDER
7Abnormal visionSIDER
8Altered state of consciousnessSIDER
9Anaphylactic shockSIDER
10AnorexiaSIDER
11ArthralgiaSIDER
12AstheniaSIDER
13Back PainSIDER
14Cerebrovascular accidentSIDER
15Chest PainSIDER
16ChillsSIDER
17ConstipationSIDER
18Depressed Level of ConsciousnessSIDER
19DermatitisSIDER
20DisabilitySIDER
21DiscomfortSIDER
22DizzinessSIDER
23DyspepsiaSIDER
24FatigueSIDER
25Feeling abnormalSIDER
26Gastrointestinal PainSIDER
27HeadacheSIDER
28Hemolytic reactionSIDER
29Hypertensive crisisSIDER
30Long QT Syndrome

View details

7570888
8009050
8600755
15934850
 		CTD
31Lysosomal Storage Diseases28551711CTD
32Malaria, Falciparum15215119
15893244		CTD
33Malaria8116811
15934850
17404338		CTD
34Musculoskeletal discomfortSIDER
35MyalgiaSIDER
36NauseaSIDER
37PalpitationsSIDER
38PruritusSIDER
39Romano-Ward Syndrome8009050
8124107		CTD
40StomatitisSIDER
41TetanySIDER
42TinnitusSIDER
43Torsades de Pointes8124107CTD
44UrticariaSIDER
45Visual ImpairmentSIDER
46VomitingSIDER
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