MetaADEDB 2.0 @ LMMD
tafenoquine
(LBHLFPGPEGDCJG-UHFFFAOYSA-N)
Structure
SMILES
NCCCC(Nc1cc(OC)c(c2c1nc(OC)cc2C)Oc1cccc(c1)C(F)(F)F)C
Type(s)
Approved; Investigational
Molecular Formula:
C24H28F3N3O3
Molecular Weight:
463.493
Log P:
6.6841
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
78.63
CAS Number(s):
106635-80-7
Synonym(s)
1.
tafenoquine
2.
N(4)-(2,6-dimethoxy-4-methyl-5-((3-trifluoromethyl)phenoxy)-8-quinolinyl)-1,4-pentanediamine
3.
WR 238605
4.
WR-238605
5.
tafenoquine maleate
6.
tafenoquine succinate
External Link(s)
MeSHC055852
PubChem Compound115358
ChEBI141487
CHEMBLCHEMBL298470
DrugBankDB06608
DrugCentral3578
IUPHAR/BPS Guide to PHARMACOLOGY9722
KEGGdr:D10490
Therapeutic Target DatabaseD07TWN
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Post-Traumatic Stress DisorderFAERS: 11US FAERS
2TinnitusFAERS: 11US FAERS
3AngerFAERS: 10US FAERS
4AnxietyFAERS: 10US FAERS
5HeadacheFAERS: 7US FAERS
6ParanoiaFAERS: 7US FAERS
7DizzinessFAERS: 6US FAERS
8Irritable Bowel SyndromeFAERS: 6US FAERS
9MalaiseFAERS: 6US FAERS
10Suicide attemptFAERS: 6US FAERS
11Depressed moodFAERS: 5US FAERS
12Memory impairmentFAERS: 5US FAERS
13Mood swingsFAERS: 5US FAERS
14AmnesiaFAERS: 4US FAERS
15General physical health deteriorationFAERS: 4US FAERS
16Loss of personal independence in daily activitiesFAERS: 4US FAERS
17VertigoFAERS: 4US FAERS
18AstheniaFAERS: 3US FAERS
19SchizophreniaFAERS: 3US FAERS
20ScreamingFAERS: 3US FAERS
21TremorFAERS: 3US FAERS
22AbuliaFAERS: 2US FAERS
23AgitationFAERS: 2US FAERS
24Alcohol abuseFAERS: 2US FAERS
25Bipolar DisorderFAERS: 2US FAERS
26CryingFAERS: 2US FAERS
27DeafnessFAERS: 2US FAERS
28DehydrationFAERS: 2US FAERS
29Emotional distressFAERS: 2US FAERS
30Feeling abnormalFAERS: 2US FAERS
31HypervigilanceFAERS: 2US FAERS
32Hypothalamo-pituitary disorderFAERS: 2US FAERS
33Mental impairmentFAERS: 2US FAERS
34NauseaFAERS: 2US FAERS
35Personality ChangeFAERS: 2US FAERS
36Product use issueFAERS: 2US FAERS
37RestlessnessFAERS: 2US FAERS
38Abdominal PainFAERS: 1US FAERS
39Acute kidney injuryFAERS: 1US FAERS
40Cerebrovascular accidentFAERS: 1US FAERS
41Chest PainFAERS: 1US FAERS
42Completed SuicideFAERS: 1US FAERS
43Dengue FeverFAERS: 1US FAERS
44Dissociative disorderFAERS: 1US FAERS
45Drug ineffectiveFAERS: 1US FAERS
46DysphemiaFAERS: 1US FAERS
47Emotional disorderFAERS: 1US FAERS
48FatigueFAERS: 1US FAERS
49Frustration tolerance decreasedFAERS: 1US FAERS
50Head discomfortFAERS: 1US FAERS
51HyperacusisFAERS: 1US FAERS
52Impaired work abilityFAERS: 1US FAERS
53IncoherentFAERS: 1US FAERS
54Intrusive thoughtsFAERS: 1US FAERS
55MalariaFAERS: 1US FAERS
56Mental FatigueFAERS: 1US FAERS
57MiliariaFAERS: 1US FAERS
58Multiple SclerosisFAERS: 1US FAERS
59Muscle tightnessFAERS: 1US FAERS
60MyalgiaFAERS: 1US FAERS
61NephrolithiasisFAERS: 1US FAERS
62Neuropsychiatric syndromeFAERS: 1US FAERS
63Oropharyngeal spasmFAERS: 1US FAERS
64PainFAERS: 1US FAERS
65PhotophobiaFAERS: 1US FAERS
66Physical assaultFAERS: 1US FAERS
67Plasmodium vivax infectionFAERS: 1US FAERS
68PoisoningFAERS: 1US FAERS
69Product prescribing issueFAERS: 1US FAERS
70Psychiatric symptomFAERS: 1US FAERS
71Stress at workFAERS: 1US FAERS
72Struck by lightningFAERS: 1US FAERS
73SwellingFAERS: 1US FAERS
74Toxicity to various agentsFAERS: 1US FAERS
75Visual ImpairmentFAERS: 1US FAERS
76Vitreous floatersFAERS: 1US FAERS
77Weight decreasedFAERS: 1US FAERS
78Leishmaniasis20837750CTD
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