MetaADEDB 2.0 @ LMMD
Protriptyline
(BWPIARFWQZKAIA-UHFFFAOYSA-N)
Structure
SMILES
CNCCCC1c2ccccc2C=Cc2c1cccc2
Type(s)
Approved
ATC code(s)
N06AA11
Molecular Formula:
C19H21N
Molecular Weight:
263.377
Log P:
4.6928
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
1
TPSA:
12.03
CAS Number(s):
438-60-8; 1225-55-4
Synonym(s)
1.
Protriptyline
2.
Protriptyline Hydrochloride
3.
Vivactil
4.
Hydrochloride, Protriptyline
External Link(s)
MeSHD011530
PubChem Compound4976
BindingDB50176062
ChEBI8597
CHEMBLCHEMBL668
DrugBankDB00344
DrugCentral2320
IUPHAR/BPS Guide to PHARMACOLOGY7285
KEGGcpd:C07408
dr:D08447
Therapeutic Target DatabaseD00MYQ
ZINC1530764
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 2US FAERS
2Blood pressure orthostatic decreasedFAERS: 1US FAERS
3DysgeusiaFAERS: 1SIDER
US FAERS
4Electrocardiogram changeFAERS: 1US FAERS
5HypersensitivityFAERS: 1US FAERS
6Sinus TachycardiaFAERS: 1US FAERS
7SyncopeFAERS: 1US FAERS
8TremorFAERS: 17334152CTD
SIDER
US FAERS
9Troponin increasedFAERS: 1US FAERS
10Abdominal CrampsSIDER
11Abdominal PainSIDER
12Acute Coronary SyndromeSIDER
13AdenitisSIDER
14AgitationSIDER
15AgranulocytosisSIDER
16AlopeciaSIDER
17AnorexiaSIDER
18AnxietySIDER
19AstheniaSIDER
20AtaxiaSIDER
21Atrioventricular BlockSIDER
22Bipolar Disorder7446789CTD
23Black hairy tongueSIDER
24Bone marrow depressionSIDER
25Catalepsy9567763CTD
26Cataplexy6976152CTD
27Cerebrovascular accidentSIDER
28ConstipationSIDER
29Depressive disorder4671919
5578096		CTD
30DermatitisSIDER
31DiscomfortSIDER
32DisorientationSIDER
33Disturbance in sexual arousalSIDER
34DizzinessSIDER
35DrowsinessSIDER
36Drug withdrawal syndromeSIDER
37DyspepsiaSIDER
38EosinophiliaSIDER
39Epigastric distressSIDER
40Epilepsy5823053CTD
41Erectile dysfunction3957884CTD
SIDER
42FatigueSIDER
43Feeling abnormalSIDER
44FlushingSIDER
45HeadacheSIDER
46HyperpyrexiaSIDER
47HypomaniaSIDER
48Hypotension, Orthostatic6465015
6711426
7105622		CTD
49HypotensionSIDER
50LeukopeniaSIDER
51LymphadenitisSIDER
52MalaiseSIDER
53Malaria23129054CTD
54MydriasisSIDER
55Myocardial InfarctionSIDER
56NauseaSIDER
57NocturiaSIDER
58NumbnessSIDER
59PalpitationsSIDER
60PancytopeniaSIDER
61Paresthesia of limbsSIDER
62Parotid swellingSIDER
63PetechiaeSIDER
64PruritusSIDER
65PurpuraSIDER
66Somnambulism453369CTD
67SomnolenceSIDER
68StomatitisSIDER
69Substance Withdrawal Syndrome7446789CTD
70Tachycardia, Ventricular463940CTD
71TachycardiaSIDER
72Taste peculiarSIDER
73ThrombocytopeniaSIDER
74Tinnitus7334152CTD
SIDER
75Urinary RetentionSIDER
76UrticariaSIDER
77Vascular purpuraSIDER
78Ventricular Fibrillation463940CTD
79VomitingSIDER
80Xerostomia7334152CTD
81jaundiceSIDER
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