xylometazoline
(HUCJFAOMUPXHDK-UHFFFAOYSA-N)
Structure
- SMILES
- Cc1cc(cc(c1CC1=NCCN1)C)C(C)(C)C
- Type(s)
- Approved; Investigational
- ATC code(s)
- R01AA07; R01AB06; S01GA03; S01GA53
- Molecular Formula:
- C16H24N2
- Molecular Weight:
- 244.375
- Log P:
- 2.9095
- Hydrogen Bond Acceptor:
- 2
- Hydrogen Bond Donor:
- 1
- TPSA:
- 24.39
- CAS Number(s):
- 526-36-3; 1218-35-5
Synonym(s)
1.
xylometazoline
2.
2-(4'-tert-butyl-2',6'-dimethylphenylmethyl)imidazoline
3.
Amidrin
4.
Balkis
5.
Chlorohist-LA
6.
Decongest
7.
Gelonasal
8.
Idasal
9.
Idril N
10.
Imidin
11.
Nasan
12.
NasenGel ratiopharm
13.
NasenSpray ratiopharm
14.
NasenTropfen ratiopharm
15.
Nasengel AL
16.
Nasenspray AL
17.
Nasentropfen AL
18.
Novorin
19.
Otradrops
20.
Otraspray
21.
Otriven
22.
Otrivin
23.
Otrivin Mentol
24.
Rapako
25.
Snup
26.
espa-rhin
27.
schnupfen endrine
28.
stas
29.
xylometazoline hydrochloride
30.
xylometazoline monohydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug Dependence | FAERS: 183 Canada Vigilance: 24 | Canada Vigilance US FAERS | |
| 2 | Incorrect drug administration duration | FAERS: 71 | OFFSIDES US FAERS | |
| 3 | Intentional drug misuse | FAERS: 34 | OFFSIDES US FAERS | |
| 4 | Overdose | FAERS: 20 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 5 | Drug ineffective | FAERS: 14 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 6 | Rebound effect | FAERS: 14 Canada Vigilance: 3 | Canada Vigilance OFFSIDES US FAERS | |
| 7 | Anosmia | FAERS: 13 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 8 | Incorrect dose administered | FAERS: 12 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Epistaxis | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Maternal exposure during pregnancy | FAERS: 9 | US FAERS | |
| 11 | Inappropriate schedule of drug administration | FAERS: 8 | OFFSIDES US FAERS | |
| 12 | Anxiety | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Palpitations | FAERS: 7 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 14 | Drug abuse | FAERS: 6 Canada Vigilance: 12 | Canada Vigilance US FAERS | |
| 15 | Drug exposure during pregnancy | FAERS: 6 | OFFSIDES US FAERS | |
| 16 | Ageusia | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 17 | Dizziness | FAERS: 5 | OFFSIDES US FAERS | |
| 18 | Headache | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 19 | Hypersensitivity | FAERS: 5 | US FAERS | |
| 20 | Wrong technique in drug usage process | FAERS: 5 | OFFSIDES US FAERS | |
| 21 | Incorrect route of drug administration | FAERS: 4 | US FAERS | |
| 22 | Malaise | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 23 | Nasal discomfort | FAERS: 4 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 24 | Pain | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 25 | Tachycardia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 26 | Therapeutic response unexpected | FAERS: 4 | US FAERS | |
| 27 | Diabetes Mellitus | FAERS: 3 | US FAERS | |
| 28 | Erythema | FAERS: 3 | US FAERS | |
| 29 | Feeling abnormal | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 30 | Infection | FAERS: 3 | US FAERS | |
| 31 | No adverse drug reaction | FAERS: 3 | US FAERS | |
| 32 | Wrong technique in product usage process | FAERS: 3 | US FAERS | |
| 33 | Accidental drug intake by child | FAERS: 2 | US FAERS | |
| 34 | Application site pain | FAERS: 2 | OFFSIDES US FAERS | |
| 35 | Bradycardia | FAERS: 2 | US FAERS | |
| 36 | Disease recurrence | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 37 | Dysgeusia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 38 | Influenza | FAERS: 2 | US FAERS | |
| 39 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 40 | Pregnancy | FAERS: 2 | US FAERS | |
| 41 | Rhinitis | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 42 | Sinus Arrhythmia | FAERS: 2 | US FAERS | |
| 43 | Sinusitis | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 44 | Somnolence | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 45 | Syncope | FAERS: 2 | US FAERS | |
| 46 | Tremor | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 47 | jaundice | FAERS: 2 | US FAERS | |
| 48 | Arthralgia | FAERS: 1 | US FAERS | |
| 49 | Arthritis | FAERS: 1 | US FAERS | |
| 50 | Asthenia | FAERS: 1 | OFFSIDES US FAERS | |
| 51 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 52 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 53 | Burning sensation | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 54 | Cheilitis | FAERS: 1 | US FAERS | |
| 55 | Chest discomfort | FAERS: 1 | US FAERS | |
| 56 | Claustrophobia | FAERS: 1 | US FAERS | |
| 57 | Depressed mood | FAERS: 1 | US FAERS | |
| 58 | Drug administered to patient of inappropriate age | FAERS: 1 | US FAERS | |
| 59 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 60 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 61 | Dysphonia | FAERS: 1 | US FAERS | |
| 62 | Dysuria | FAERS: 1 | US FAERS | |
| 63 | Ear discomfort | FAERS: 1 | US FAERS | |
| 64 | Expired drug administered | FAERS: 1 | US FAERS | |
| 65 | Expired product administered | FAERS: 1 | US FAERS | |
| 66 | Eye pain | FAERS: 1 | US FAERS | |
| 67 | Fatigue | FAERS: 1 | OFFSIDES US FAERS | |
| 68 | Glaucoma | FAERS: 1 | US FAERS | |
| 69 | Glucose tolerance increased | FAERS: 1 | US FAERS | |
| 70 | Hepatitis C | FAERS: 1 | US FAERS | |
| 71 | Hernia perforation | FAERS: 1 | US FAERS | |
| 72 | Hyperventilation | FAERS: 1 | US FAERS | |
| 73 | Incorrect product storage | FAERS: 1 | US FAERS | |
| 74 | Lip swelling | FAERS: 1 | US FAERS | |
| 75 | Macular degeneration | FAERS: 1 | US FAERS | |
| 76 | Mouth swelling | FAERS: 1 | US FAERS | |
| 77 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 78 | Myopia | FAERS: 1 | US FAERS | |
| 79 | Nasal mucosal disorder | FAERS: 1 | US FAERS | |
| 80 | Nasopharyngitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 81 | No adverse event | FAERS: 1 | US FAERS | |
| 82 | Optic Neuritis | FAERS: 1 | US FAERS | |
| 83 | Pallor | FAERS: 1 | US FAERS | |
| 84 | Panic Disorder | FAERS: 1 | US FAERS | |
| 85 | Poisoning | FAERS: 1 | US FAERS | |
| 86 | Polyneuropathy chronic | FAERS: 1 | US FAERS | |
| 87 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 88 | Positron emission tomogram abnormal | FAERS: 1 | US FAERS | |
| 89 | Product container issue | FAERS: 1 | US FAERS | |
| 90 | Product contamination | FAERS: 1 | US FAERS | |
| 91 | Pruritus | FAERS: 1 | US FAERS | |
| 92 | Restlessness | FAERS: 1 | US FAERS | |
| 93 | Retinal Artery Occlusion | FAERS: 1 | US FAERS | |
| 94 | Scab | FAERS: 1 | US FAERS | |
| 95 | Skin reaction | FAERS: 1 | US FAERS | |
| 96 | Suicide attempt | FAERS: 1 | US FAERS | |
| 97 | Swelling | FAERS: 1 | US FAERS | |
| 98 | Urticaria | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 99 | Visual Impairment | FAERS: 1 | US FAERS | |
| 100 | Vomiting | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 101 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 102 | Yawning | FAERS: 1 | US FAERS | |
| 103 | Abnormal vision | OFFSIDES | ||
| 104 | Abuse | OFFSIDES | ||
| 105 | Anaphylactic shock | Canada Vigilance: 1 | Canada Vigilance | |
| 106 | Aneurysm | Canada Vigilance: 1 | Canada Vigilance | |
| 107 | Application site reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 108 | Arthropod sting | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Atrial tachycardia | OFFSIDES | ||
| 110 | Autoimmune hepatitis | OFFSIDES | ||
| 111 | Benign Prostatic Hyperplasia | OFFSIDES | ||
| 112 | Blepharospasm | OFFSIDES | ||
| 113 | Blood cortisol decreased | OFFSIDES | ||
| 114 | Blood creatinine decreased | OFFSIDES | ||
| 115 | Bronchospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 116 | Catalepsy | 35781 35783 | CTD | |
| 117 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | Choking sensation | OFFSIDES | ||
| 119 | Common Cold | 20030735 | CTD | |
| 120 | Conjunctival deposit | OFFSIDES | ||
| 121 | Craniotomy | OFFSIDES | ||
| 122 | Deafness | OFFSIDES | ||
| 123 | Decreased Libido | OFFSIDES | ||
| 124 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 125 | Dementia | Canada Vigilance: 2 | Canada Vigilance | |
| 126 | Drug addict | OFFSIDES | ||
| 127 | Drug ineffective for unapproved indication | Canada Vigilance: 1 | Canada Vigilance | |
| 128 | Exposure via breast milk | Canada Vigilance: 1 | Canada Vigilance | |
| 129 | Formication | OFFSIDES | ||
| 130 | Hepatic necrosis | OFFSIDES | ||
| 131 | Hormone level abnormal | OFFSIDES | ||
| 132 | Incorrect product administration duration | Canada Vigilance: 3 | Canada Vigilance | |
| 133 | Inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 134 | Intentional product misuse | Canada Vigilance: 1 | Canada Vigilance | |
| 135 | Lethargy | Canada Vigilance: 1 | Canada Vigilance | |
| 136 | Lymphocyte count decreased | OFFSIDES | ||
| 137 | Medication Error | Canada Vigilance: 1 | Canada Vigilance | |
| 138 | Muscle Weakness | OFFSIDES | ||
| 139 | Nasal Polyps | Canada Vigilance: 1 | Canada Vigilance | |
| 140 | Nausea | Canada Vigilance: 2 | Canada Vigilance | |
| 141 | Purulent discharge | Canada Vigilance: 1 | Canada Vigilance | |
| 142 | Respiratory distress | Canada Vigilance: 1 | Canada Vigilance | |
| 143 | Secondary hypothyroidism | OFFSIDES | ||
| 144 | Sneezing | Canada Vigilance: 1 | Canada Vigilance | |
| 145 | Spinal column stenosis | OFFSIDES | ||
| 146 | Temperature intolerance | OFFSIDES | ||
| 147 | Throat irritation | Canada Vigilance: 1 | Canada Vigilance | |
| 148 | Tinnitus | OFFSIDES |
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