MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Celiprolol

(JOATXPAWOHTVSZ-UHFFFAOYSA-N)

Structure

SMILES: CCN(C(=O)Nc1ccc(c(c1)C(=O)C)OCC(CNC(C)(C)C)O)CC
Type(s): Approved; Investigational
ATC code(s): C07AB08
Molecular Formula:: C20H33N3O4
Molecular Weight:: 379.494
Log P:: 3.3546
Hydrogen Bond Acceptor:: 7
Hydrogen Bond Donor:: 3
TPSA:: 90.9
CAS Number(s):: 56980-93-9

Synonym(s)

Celiprolol

Celiprolol Hydrochloride

Celiprolol Monohydrochloride

Celiprolol, (+,-)-Isomer

Celiprolol, (R)-Isomer

Celiprolol, (S)-Isomer

Celiprolol, Monohydrochloride, (R)-Isomer

Celiprolol, Monohydrochloride, (S)-Isomer

N'-(3-Acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)-N,N-diethylurea

10.

REV-5320A

11.

ST-1396

12.

Selectol

13.

Hydrochloride, Celiprolol

14.

Monohydrochloride, Celiprolol

15.

REV 5320A

16.

REV5320A

17.

ST 1396

18.

ST1396

External Link(s)

MeSH	D017272
PubChem Compound	2663
ChEBI	94461
CHEMBL	CHEMBL27810
DrugBank	DB04846
DrugCentral	569
IUPHAR/BPS Guide to PHARMACOLOGY	9064
KEGG	dr:D07660

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	ANA increased		SIDER
2	Abdominal Pain		SIDER
3	Adenocarcinoma		OFFSIDES
4	Agraphia		OFFSIDES
5	Angina Pectoris	2571590	CTD
6	Angioedema		OFFSIDES
7	Anti-insulin antibody positive		OFFSIDES
8	Antinuclear antibody increased		SIDER
9	Anuria		OFFSIDES
10	Apathy		OFFSIDES
11	Aphagia		OFFSIDES
12	Asthenia		OFFSIDES SIDER
13	Atrioventricular Block		SIDER
14	Bile Duct Stenosis		OFFSIDES
15	Blood alkaline phosphatase increased		OFFSIDES
16	Blood chloride decreased		OFFSIDES
17	Blood creatine phosphokinase increased		OFFSIDES
18	Blood creatinine increased		OFFSIDES
19	Blood glucose decreased		OFFSIDES
20	Blood immunoglobulin A increased		OFFSIDES
21	Blood lactate dehydrogenase increased		OFFSIDES
22	Blood osmolarity decreased		OFFSIDES
23	Blood potassium increased		OFFSIDES
24	Blood pressure inadequately controlled		OFFSIDES
25	Blood sodium		OFFSIDES
26	Blood urea increased		OFFSIDES
27	Bradycardia		OFFSIDES SIDER
28	Bronchoalveolar Lavage		OFFSIDES
29	Bronchopneumopathy		OFFSIDES
30	Bronchospasm		SIDER
31	Calcification pancreatic duct		OFFSIDES
32	Calciphylaxis		OFFSIDES
33	Cell Death		OFFSIDES
34	Cerebral atrophy		OFFSIDES
35	Cheilitis		OFFSIDES
36	Cholestatic liver injury		OFFSIDES
37	Complement factor C3 increased		OFFSIDES
38	Concomitant disease aggravated		OFFSIDES
39	Confabulation		OFFSIDES
40	Creatinine renal clearance decreased		OFFSIDES
41	Cyst		OFFSIDES
42	Cytolytic hepatitis		OFFSIDES
43	Dehydration		OFFSIDES
44	Dermatitis		SIDER
45	Diabetes Mellitus		SIDER
46	Disseminated Intravascular Coagulation		OFFSIDES
47	Dizziness		SIDER
48	Drowsiness		OFFSIDES
49	Drug Tolerance		OFFSIDES
50	Duodenal Ulcer		OFFSIDES
51	Eczema		OFFSIDES
52	Electrocardiogram repolarisation abnormality		OFFSIDES
53	Enterocolitis		OFFSIDES
54	Epilepsy		OFFSIDES
55	Erythema Multiforme		OFFSIDES
56	Erythema		OFFSIDES
57	Fatigue		SIDER
58	Feeling abnormal		SIDER
59	Gamma-Glutamyltransferase Increased		OFFSIDES
60	Gamma-glutamyltransferase abnormal		OFFSIDES
61	Gastroenteritis		OFFSIDES
62	Gastrointestinal motility disorder		OFFSIDES
63	Gastrointestinal mucosal necrosis		OFFSIDES
64	Gastrointestinal tract adenoma		OFFSIDES
65	General physical health deterioration		OFFSIDES
66	Glossitis		OFFSIDES
67	Granulocytosis		OFFSIDES
68	Guttate psoriasis		OFFSIDES
69	Headache		SIDER
70	Heart failure	15849448	CTD
71	Hypercreatinaemia		OFFSIDES
72	Hyperthyroidism		SIDER
73	Hypophagia		OFFSIDES
74	Hypotension	1973398	CTD SIDER
75	Ileitis		OFFSIDES
76	Incisional hernia		OFFSIDES
77	Incorrect route of drug administration		OFFSIDES
78	Injection site warmth		OFFSIDES
79	Intermittent Claudication		SIDER
80	Joint sprain		OFFSIDES
81	Kidney Failure		OFFSIDES
82	Laboratory test interference		OFFSIDES
83	Lymphoma		OFFSIDES
84	Monocyte percentage decreased		OFFSIDES
85	Monoparesis		OFFSIDES
86	Mucocutaneous candidiasis		OFFSIDES
87	Multiple drug overdose		OFFSIDES
88	Nausea		SIDER
89	Nephrogenic Fibrosing Dermopathy		OFFSIDES
90	Neutropenic sepsis		OFFSIDES
91	Optic Disc Edema		OFFSIDES
92	Oral polypectomy		OFFSIDES
93	Overdose		OFFSIDES
94	Palpitations		SIDER
95	Phlebitis		OFFSIDES
96	Pleurisy		OFFSIDES
97	Psoriasis		OFFSIDES
98	Pyuria		OFFSIDES
99	Renal scan abnormal		OFFSIDES
100	Scan abdomen abnormal		OFFSIDES
101	Sclerosing encapsulating peritonitis		OFFSIDES
102	Sjogren's Syndrome		OFFSIDES
103	Skin lesion		OFFSIDES
104	Skin test positive		OFFSIDES
105	Small bowel angioedema		OFFSIDES
106	Somnolence		SIDER
107	Starvation		OFFSIDES
108	Stomach ache		SIDER
109	Strawberry tongue		OFFSIDES
110	Subileus		OFFSIDES
111	Sudden death		OFFSIDES
112	Tachycardia, Ventricular	1973400	CTD
113	Tachycardia		SIDER
114	Tendinitis		OFFSIDES
115	Tetany		OFFSIDES
116	Thyrotoxicosis		SIDER
117	Tinea Pedis		OFFSIDES
118	Tonsillitis		OFFSIDES
119	Tremor		SIDER
120	Umbilical hernia		OFFSIDES
121	Visual Impairment		SIDER
122	Visual disturbance		SIDER
123	Vomiting		SIDER
124	colonoscopy		OFFSIDES

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