MetaADEDB 2.0 @ LMMD
Apoptosis
(UMLS:C0162638)
Definition:
A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically-programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.|Physiological forms of regulated cell death that occur during growth and development and tissue turnover.
UMLS ID:
C0162638
MeSH ID:
D017209
Classification:
Name:
Cell Physiological Phenomena
MeSH Tree Number(s):
G04.146.160
Synonym(s)
1.
Apoptosis
2.
APOPTOSIS
3.
Apoptotic Process
4.
Gene-directed cell death
5.
Mechanism that allows cells to self-destruct when it is necessary
6.
Programmed Cell Death
7.
apoptose
8.
apoptosis
9.
apoptotic cell death
10.
apoptotic process
11.
apoptotic programmed cell death
12.
programmed cell death
13.
programmed cell death by apoptosis
14.
self destruction of the cell
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1Mycophenolic AcidFAERS: 33US FAERS
2Mycophenolic AcidFAERS: 32US FAERS
3IbuprofenFAERS: 6
Canada Vigilance: 3		Canada Vigilance
US FAERS
4MethamphetamineFAERS: 3US FAERS
5MinocyclineFAERS: 3US FAERS
6AcetaminophenFAERS: 2OFFSIDES
US FAERS
7CephalexinFAERS: 2US FAERS
8LamotrigineFAERS: 2US FAERS
9AtorvastatinFAERS: 1US FAERS
10CapecitabineFAERS: 1US FAERS
11CiprofloxacinFAERS: 1US FAERS
12DigoxinFAERS: 1US FAERS
13DocetaxelFAERS: 1US FAERS
14FluconazoleFAERS: 1US FAERS
15FluvastatinFAERS: 1US FAERS
16HydrocortisoneFAERS: 1US FAERS
17LenalidomideFAERS: 1US FAERS
18OctreotideFAERS: 1US FAERS
19Olmesartan MedoxomilFAERS: 1US FAERS
20RifampinFAERS: 1US FAERS
21idelalisibFAERS: 1US FAERS
22AzithromycinOFFSIDES
23Calcium CarbonateOFFSIDES
24ChlorambucilOFFSIDES
25CytarabineOFFSIDES
26DimethindeneOFFSIDES
27Duloxetine HydrochlorideOFFSIDES
28GemfibrozilOFFSIDES
29LisinoprilOFFSIDES
30MelphalanOFFSIDES
31MethamphetamineOFFSIDES
32MethotrexateOFFSIDES
33ProcarbazineOFFSIDES
34RifabutinOFFSIDES
35Risedronic AcidOFFSIDES
36SunitinibSIDER
37VinblastineOFFSIDES
38fludarabineOFFSIDES
39gemcitabineCanada Vigilance: 1Canada Vigilance
Similar ADE(s)
NameSemantic Similarity
1Necrosis28.6%
2Clonal Evolution15.8%
3DNA Degradation, Necrotic15.5%
4Diapedesis9.2%
5Phagocytosis5.8%
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