MetaADEDB 2.0 @ LMMD
Tachyphylaxis
(UMLS:C0039242)
Definition:
Rapidly decreasing response to a drug or physiologically active agent after administration of a few doses. In immunology, it is the rapid immunization against the effect of toxic doses of an extract or serum by previous injection of small doses. (Dorland, 28th ed)
UMLS ID:
C0039242
MeSH ID:
D013618
Classification 1:
Name:
Physiological Phenomena
MeSH Tree Number(s):
G07.690.773.992.910
Classification 2:
Name:
Immune System Phenomena
MeSH Tree Number(s):
G12.535.425.910
Synonym(s)
1.
Tachyphylaxis
2.
TACHYPHYLAXIS
3.
tachyphylaxis
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1CabergolineFAERS: 5US FAERS
2CitalopramFAERS: 4US FAERS
3Rosuvastatin CalciumFAERS: 4US FAERS
4tegaserodFAERS: 4OFFSIDES
US FAERS
5PregabalinFAERS: 3US FAERS
6SunitinibFAERS: 3OFFSIDES
US FAERS
7Vardenafil DihydrochlorideFAERS: 3OFFSIDES
US FAERS
8AripiprazoleFAERS: 2OFFSIDES
US FAERS
9DeferasiroxFAERS: 2OFFSIDES
US FAERS
10Desvenlafaxine SuccinateFAERS: 2US FAERS
11DiazepamFAERS: 2US FAERS
12DoxycyclineFAERS: 2US FAERS
13OctreotideFAERS: 2OFFSIDES
US FAERS
14OmeprazoleFAERS: 2US FAERS
15linaclotideFAERS: 2US FAERS
16mirabegronFAERS: 2US FAERS
17naloxegolFAERS: 2US FAERS
18ropiniroleFAERS: 2OFFSIDES
US FAERS
19AlbuterolFAERS: 1US FAERS
20Atomoxetine HydrochlorideFAERS: 1US FAERS
21AtorvastatinFAERS: 1US FAERS
22AzithromycinFAERS: 1US FAERS
23BaclofenFAERS: 1US FAERS
24BuprenorphineFAERS: 1US FAERS
25CyclosporineFAERS: 1US FAERS
26EsomeprazoleFAERS: 1US FAERS
27FentanylFAERS: 1US FAERS
28Fexofenadine hydrochloride and pseudoephedrine hydrochlorideFAERS: 1US FAERS
29Fluticasone-Salmeterol Drug CombinationFAERS: 1US FAERS
30FluticasoneFAERS: 1US FAERS
31IpratropiumFAERS: 1US FAERS
32IrinotecanFAERS: 1US FAERS
33Lisdexamfetamine DimesylateFAERS: 1US FAERS
34LosartanFAERS: 1US FAERS
35PantoprazoleFAERS: 1US FAERS
36Quetiapine FumarateFAERS: 1US FAERS
37RanitidineFAERS: 1US FAERS
38Sildenafil CitrateFAERS: 1US FAERS
39Solifenacin SuccinateFAERS: 1US FAERS
40TadalafilFAERS: 1US FAERS
41TamsulosinFAERS: 1US FAERS
42Tiotropium BromideFAERS: 1US FAERS
43TirofibanFAERS: 1US FAERS
44TramadolFAERS: 1US FAERS
45Vortioxetine hydrobromideFAERS: 1US FAERS
46cisatracuriumFAERS: 1US FAERS
47insulin aspart, insulin aspart protamine drug combination 30:70FAERS: 1US FAERS
48liposomal doxorubicinFAERS: 1US FAERS
49salmon calcitoninFAERS: 1US FAERS
50tafluprostFAERS: 1US FAERS
51tofacitinibFAERS: 1US FAERS
52ziprasidoneFAERS: 1US FAERS
53BupivacaineOFFSIDES
54Desvenlafaxine SuccinateOFFSIDES
55FinasterideCanada Vigilance: 2Canada Vigilance
56GuanfacineOFFSIDES
57LamotrigineOFFSIDES
58MethotrexateCanada Vigilance: 1Canada Vigilance
59NateglinideOFFSIDES
60NitroglycerinCanada Vigilance: 1Canada Vigilance
61OctreotideCanada Vigilance: 1Canada Vigilance
62PentazocineCanada Vigilance: 1Canada Vigilance
63SevelamerOFFSIDES
64SevelamerOFFSIDES
65SuccinylcholineSIDER
66SunitinibOFFSIDES
67TetracyclineOFFSIDES
68Valproic AcidOFFSIDES
69alfacalcidolOFFSIDES
70dofetilideOFFSIDES
71fexofenadineCanada Vigilance: 1Canada Vigilance
72tegaserodOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Drug resistance23.1%
2Insulin Resistance11.4%
3Phagocytosis8.2%
4Body Temperature7.8%
5Macrophage Activation6.7%
6Oxidative Stress4.4%
7Disease susceptibility4.2%
8Breast Feeding3.5%
9Sweating3.3%
10Fasting2.6%
11Shivering2.6%
12Anion Gap2.5%
13Body Height2.2%
14Hunger2%
15Bottle feeding1.9%
16Body Weight1.9%
17Diapedesis1.7%
18Body mass index1.6%
19Somatosensory Evoked Potentials1.6%
20Fetal Weight1.6%
21Birth Weight1.4%
22Body Weight Changes1.2%
23Ketogenic Diet1.2%
24Weight Gain1%
25Underweight1%
26Overweight1%
27Obesity, Abdominal0.7%
28Obesity0.7%
29Pediatric Obesity0.6%
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