MetaADEDB 2.0 @ LMMD
Genetic Polymorphism
(UMLS:C0032529)
Definition:
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
UMLS ID:
C0032529
MeSH ID:
D011110
Classification:
Name:
Genetic Phenomena
MeSH Tree Number(s):
G05.365.795
Synonym(s)
1.
Genetic Polymorphism
2.
Genetic polymorphism
3.
Genetic polymorphisms
4.
Polymorphism
5.
genetic polymorphism
6.
polymorphism
7.
polymorphisms
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1BromocriptineFAERS: 1US FAERS
2EstradiolFAERS: 1US FAERS
3SimvastatinFAERS: 1US FAERS
4AzithromycinSIDER
5IrinotecanSIDER
Similar ADE(s)
NameSemantic Similarity
1Genomic Instability27.3%
2Mosaicism25.4%
3Chimerism25.4%
4Chromosome Aberrations20.9%
5Aneuploidy19.7%
6Polyploidy19.7%
7Microsatellite Instability19.7%
8Trisomy18%
9Chromosome Breakage17.6%
10Sex Chromosome Aberrations16.9%
11Monosomy16.2%
12Tetraploidy16.2%
13Clonal Evolution15.8%
14Chromosomal Instability15.6%
15Chromosome Fragility12.9%
16Enzyme Induction10.3%
17Philadelphia Chromosome10%
18Micronuclei, Chromosome-Defective9.9%
19DNA Degradation, Necrotic6.9%
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120241

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.