MetaADEDB 2.0 @ LMMD
Troponin T
(UMLS:C0077404)
Definition:
A TROPONIN complex subunit that binds to TROPOMYOSIN. There are three troponin T subtypes: troponin T1, T2 and T3. Troponin T2 is cardiac-specific whereas troponin T2 and T3 are skeletal subtypes. Troponin T2 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin T2 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
UMLS ID:
C0077404
MeSH ID:
D020107
Classification 1:
Name:
Macromolecular Substances
MeSH Tree Number(s):
D05.500.945.962|D05.750.078.730.825.962
Classification 2:
Name:
Amino Acids, Peptides, and Proteins
MeSH Tree Number(s):
D12.776.210.500.910.962|D12.776.220.525.825.962
Synonym(s)
1.
Troponin T
2.
TNNT
3.
Tropomyosin-binding troponin
4.
Tropomyosin-binding troponin subunit
5.
Troponin-T
6.
t troponin
7.
tnt
8.
tnts
9.
troponin t
10.
troponin-t
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1ClozapineFAERS: 1OFFSIDES
US FAERS
2VyxeosFAERS: 1US FAERS
3pazopanibFAERS: 1US FAERS
44-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideOFFSIDES
55-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydron;chlorideOFFSIDES
6AcetaminophenOFFSIDES
7AlcoholsOFFSIDES
8AmisulprideOFFSIDES
9AmphetamineOFFSIDES
10BromocriptineOFFSIDES
11BupivacaineOFFSIDES
12CabergolineOFFSIDES
13ClotrimazoleOFFSIDES
14CocaineOFFSIDES
15DeferasiroxOFFSIDES
16EnalaprilatOFFSIDES
17EpinephrineOFFSIDES
18ErythromycinOFFSIDES
19FloxacillinOFFSIDES
20HydroxyzineOFFSIDES
21IopamidolOFFSIDES
22LevodopaOFFSIDES
23MethimazoleOFFSIDES
24MetoclopramideOFFSIDES
25NicorandilOFFSIDES
26NitratesOFFSIDES
27OxytocinOFFSIDES
28PentoxifyllineOFFSIDES
29PergolideOFFSIDES
30PravastatinOFFSIDES
31SufentanilOFFSIDES
32ThalidomideOFFSIDES
33TirofibanOFFSIDES
34TrihexyphenidylOFFSIDES
35TrimetazidineOFFSIDES
36TropisetronOFFSIDES
37VinorelbineOFFSIDES
38azosemideOFFSIDES
39isosorbide-5-mononitrateOFFSIDES
40loxoprofenOFFSIDES
41tegaserodOFFSIDES
42tegaserodOFFSIDES
43telmisartan, hydrochlorothiazide drug combinationOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Troponin I53%
2C-reactive protein15.2%
3Transferrin11.7%
4Fibrin9.7%
5beta Globulin9.7%
6Prealbumin9.7%
7procalcitonin9.3%
8Chylomicrons8.2%
9Lipoprotein (a)8.2%
10Human Chorionic Gonadotropin7.3%
11Troponin6.7%
12Cryoglobulins6.1%
13Osteocalcin5.8%
14Rheumatoid Factor5.1%
15Antiphospholipid Antibodies5.1%
16Troponin T4.4%
17Carcinoembryonic Antigen4.3%
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