MetaADEDB 2.0 @ LMMD
Nicorandil
(LBHIOVVIQHSOQN-UHFFFAOYSA-N)
Structure
SMILES
[O-][N+](=O)OCCNC(=O)c1cccnc1
Type(s)
Approved; Investigational
ATC code(s)
C01DX16
Molecular Formula:
C8H9N3O4
Molecular Weight:
211.175
Log P:
0.9338
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
97.04
CAS Number(s):
65141-46-0
Synonym(s)
1.
Nicorandil
2.
2-Nicotinamidoethyl Nitrate
3.
2-Nicotinamidethyl Nitrate
4.
Adancor
5.
Dancor
6.
Ikorel
7.
SG-75
8.
2 Nicotinamidethyl Nitrate
9.
2 Nicotinamidoethyl Nitrate
10.
Nitrate, 2-Nicotinamidethyl
11.
Nitrate, 2-Nicotinamidoethyl
12.
SG 75
13.
SG75
External Link(s)
MeSHD020108
PubChem Compound47528
BindingDB50247908
ChEBI31905
CHEMBLCHEMBL284906
DrugBankDB09220
DrugCentral1919
IUPHAR/BPS Guide to PHARMACOLOGY2411
KEGGcpd:C13280
dr:D01810
Therapeutic Target DatabaseD0O2SR
ZINC1533102
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Pain19309387CTD
SIDER
2Abnormal sleep-related eventOFFSIDES
3AbscessSIDER
4AcidosisOFFSIDES
5Acute Coronary SyndromeSIDER
6Acute kidney injury31376360CTD
7Acute myocardial infarctionOFFSIDES
8Alanine Aminotransferase IncreasedOFFSIDES
9Albuminuria22622455CTD
10Altered state of consciousnessOFFSIDES
11Anal FissureSIDER
12Angina Pectoris8271529
11791009
19309387		CTD
SIDER
13AngioedemaOFFSIDES
SIDER
14AngioplastyOFFSIDES
15AnorexiaSIDER
16Anti-insulin antibody positiveOFFSIDES
17ApathyOFFSIDES
18Arteriosclerosis ObliteransOFFSIDES
19AstheniaSIDER
20AsthmaOFFSIDES
21Back PainSIDER
22Bile Duct StenosisOFFSIDES
23Blood alkaline phosphatase increasedOFFSIDES
24Blood and lymphatic system disordersSIDER
25Blood chloride decreasedOFFSIDES
26Blood creatine phosphokinase increasedOFFSIDES
27Blood glucose decreasedOFFSIDES
28Blood lactate dehydrogenase increasedOFFSIDES
29Blood potassium increasedOFFSIDES
30Blood pressure immeasurableOFFSIDES
31Blood sodium increasedOFFSIDES
32Blood sodiumOFFSIDES
33Blood uric acidOFFSIDES
34BradycardiaOFFSIDES
35Brain Ischemia8401937CTD
36BronchitisSIDER
37Capillary Leak SyndromeOFFSIDES
38Cardiac DeathOFFSIDES
39Cardio-respiratory distressOFFSIDES
40Chest PainOFFSIDES
SIDER
41CholestasisSIDER
42ChromaturiaOFFSIDES
43Chronic left ventricular failureOFFSIDES
44CirrhosisOFFSIDES
45Conjunctival ulcerSIDER
46ConjunctivitisSIDER
47ConstipationSIDER
48CraniotomyOFFSIDES
49CyanosisOFFSIDES
50Cytolytic hepatitisOFFSIDES
51Dacryostenosis acquiredOFFSIDES
52Depressed Level of ConsciousnessOFFSIDES
53DermatitisSIDER
54Diabetes mellitus inadequate controlOFFSIDES
55DiplopiaSIDER
56DiscomfortSIDER
57Disseminated Intravascular Coagulation19309387CTD
OFFSIDES
58DizzinessSIDER
59Drug diversionOFFSIDES
60DyspepsiaSIDER
61DysuriaOFFSIDES
62EczemaOFFSIDES
63Electromechanical dissociationOFFSIDES
64Eosinophilic PneumoniaOFFSIDES
65EpistaxisOFFSIDES
SIDER
66ErysipelasOFFSIDES
67Erythema MultiformeOFFSIDES
68Fatty LiverOFFSIDES
69Feeling abnormalSIDER
70Fibrosis31376360CTD
71FlushingSIDER
72Foaming at mouthOFFSIDES
73Gamma-Glutamyltransferase IncreasedOFFSIDES
74Gastrointestinal PainSIDER
75General physical health deteriorationOFFSIDES
76HeadacheSIDER
77Hematoma19309387CTD
78Hemorrhage31376360CTD
79HepatitisSIDER
80Histiocytosis haematophagicOFFSIDES
81HyperventilationOFFSIDES
82HypocomplementaemiaOFFSIDES
83Hypotension11138733CTD
SIDER
84InfectionSIDER
85Kidney Failure, Chronic22622455CTD
86LethargySIDER
87Liver AbscessOFFSIDES
88Lymphocyte stimulation test positiveOFFSIDES
89MalaiseSIDER
90Mixed liver injuryOFFSIDES
91Muscle necrosisOFFSIDES
92Musculoskeletal discomfortSIDER
93MyalgiaSIDER
94Myocardial Infarction11829124
14527820		CTD
SIDER
95NauseaSIDER
96Neck PainSIDER
97NervousnessSIDER
98Neutrophil count decreasedOFFSIDES
99Oliguria19309387CTD
100PainSIDER
101PalpitationsSIDER
102Pancreatic InsufficiencyOFFSIDES
103Paraparesis, Spastic16551926CTD
104Percutaneous Coronary InterventionOFFSIDES
105PolyuriaOFFSIDES
106Proteinuria19262229CTD
107Prothrombin time ratio increasedOFFSIDES
108PruritusSIDER
109Pulmonary venous thrombosisOFFSIDES
110PyuriaOFFSIDES
111Renal tubular disorderOFFSIDES
112Reperfusion Injury12409977CTD
113Respiratory Distress Syndrome, Adult19309387CTD
114RhabdomyolysisOFFSIDES
115ShockSIDER
116Sinoatrial BlockOFFSIDES
117Skin necrosisOFFSIDES
118SoliloquyOFFSIDES
119SomnolenceSIDER
120StomatitisSIDER
121SubileusOFFSIDES
122Supraventricular tachycardiaOFFSIDES
123SweatingSIDER
124SyncopeSIDER
125Tachycardia, Ventricular9809951CTD
126Tachycardia19309387CTD
SIDER
127TensionSIDER
128ThrombocytopeniaSIDER
129ThyroidectomyOFFSIDES
130TinnitusSIDER
131Troponin TOFFSIDES
132Troponin increasedOFFSIDES
133UlcerSIDER
134Urticaria PigmentosaOFFSIDES
135Vasodilation procedureSIDER
136VasodilationSIDER
137Ventricular FibrillationOFFSIDES
138VertigoSIDER
139VomitingSIDER
140YawningOFFSIDES
141intensive careOFFSIDES
142jaundiceSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.