MetaADEDB 2.0 @ LMMD
Tirofiban
(COKMIXFXJJXBQG-NRFANRHFSA-N)
Structure
SMILES
CCCCS(=O)(=O)N[C@H](C(=O)O)Cc1ccc(cc1)OCCCCC1CCNCC1
Type(s)
Approved
ATC code(s)
B01AC17
Molecular Formula:
C22H36N2O5S
Molecular Weight:
440.597
Log P:
4.7510
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
3
TPSA:
113.11
CAS Number(s):
144494-65-5
Synonym(s)
1.
Tirofiban
2.
Aggrastat
3.
Agrastat
4.
L 700462
5.
L-700,462
6.
L-700462
7.
MK 383
8.
MK-383
9.
N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine
10.
Tirofiban Hydrochloride
11.
Tirofiban Hydrochloride Monohydrate
12.
L 700,462
13.
L700,462
External Link(s)
MeSHD000077466
PubChem Compound40466968
60947
BindingDB50004058
ChEBI9605
CHEMBLCHEMBL916
DrugBankDB00775
DrugCentral2680
IUPHAR/BPS Guide to PHARMACOLOGY6586
KEGGcpd:C07965
dr:D08607
Therapeutic Target DatabaseD0BN9X
ZINC3806104
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1ThrombocytopeniaFAERS: 111
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
2Myocardial InfarctionFAERS: 32SIDER
US FAERS
3Drug specific antibody presentFAERS: 10OFFSIDES
US FAERS
4ReocclusionFAERS: 7US FAERS
5Acute Coronary SyndromeFAERS: 6OFFSIDES
US FAERS
6Accidental overdoseFAERS: 4US FAERS
7Acute myocardial infarctionFAERS: 4OFFSIDES
SIDER
US FAERS
8Drug prescribing errorFAERS: 4US FAERS
9Basilar artery thrombosisFAERS: 3OFFSIDES
US FAERS
10Cardiac ArrestFAERS: 3US FAERS
11Cerebrovascular accidentFAERS: 3US FAERS
12Ventricular FibrillationFAERS: 3US FAERS
13Cardiac procedure complicationFAERS: 2OFFSIDES
US FAERS
14Coronary artery reocclusionFAERS: 2OFFSIDES
US FAERS
15Deep Vein ThrombosisFAERS: 2US FAERS
16Medication ErrorFAERS: 2US FAERS
17Sudden Cardiac DeathFAERS: 2OFFSIDES
US FAERS
18Wrong technique in product usage processFAERS: 2US FAERS
19Accidental exposureFAERS: 1US FAERS
20Antibody test positiveFAERS: 1US FAERS
21AphasiaFAERS: 1US FAERS
22Blood immunoglobulin G increasedFAERS: 1US FAERS
23Blood triglycerides increasedFAERS: 1US FAERS
24Cardiac TamponadeFAERS: 1SIDER
US FAERS
25Cerebellar infarctionFAERS: 1US FAERS
26Cerebral InfarctionFAERS: 1US FAERS
27Chest PainFAERS: 1US FAERS
28Circumstance or information capable of leading to medication errorFAERS: 1OFFSIDES
US FAERS
29Coronary artery embolismFAERS: 1US FAERS
30Depressed Level of ConsciousnessFAERS: 1US FAERS
31Disseminated Intravascular CoagulationFAERS: 1US FAERS
32EpistaxisFAERS: 1US FAERS
33Gastrointestinal angiodysplasia haemorrhagicFAERS: 1US FAERS
34General physical health deteriorationFAERS: 1US FAERS
35HemiplegiaFAERS: 1US FAERS
36Incorrect drug administration durationFAERS: 1US FAERS
37Injection site erythemaFAERS: 1US FAERS
38Injection site irritationFAERS: 1US FAERS
39Intestinal infarctionFAERS: 1US FAERS
40MonoparesisFAERS: 1US FAERS
41Platelet aggregation inhibitionFAERS: 1US FAERS
42Post procedural complicationFAERS: 1OFFSIDES
US FAERS
43Post procedural fistulaFAERS: 1US FAERS
44Post procedural myocardial infarctionFAERS: 1US FAERS
45Prescribed overdoseFAERS: 1US FAERS
46SepsisFAERS: 1US FAERS
47Stent occlusionFAERS: 1OFFSIDES
US FAERS
48Sudden deathFAERS: 1US FAERS
49Thrombosis in deviceFAERS: 1OFFSIDES
US FAERS
50Vascular stent occlusionFAERS: 1US FAERS
51Anaphylactic shockSIDER
52Arterial InjuryOFFSIDES
53AscitesOFFSIDES
54Aspiration PneumoniaOFFSIDES
55BradycardiaSIDER
56Catheter related complicationOFFSIDES
57Catheter site dischargeOFFSIDES
58Catheter site related reactionOFFSIDES
59ChillsSIDER
60Device malfunctionOFFSIDES
61DizzinessSIDER
62Electromechanical dissociationOFFSIDES
63EmbolismOFFSIDES
64Frank hematuriaSIDER
65HeadacheSIDER
66HemothoraxOFFSIDES
67HypersensitivitySIDER
68Iatrogenic injuryOFFSIDES
69Incorrect dose administeredOFFSIDES
70NauseaSIDER
71Non-Q wave MISIDER
72OverdoseOFFSIDES
73PainSIDER
74Pericardial effusionOFFSIDES
75PericarditisOFFSIDES
76Protein C decreasedOFFSIDES
77Protein S decreasedOFFSIDES
78ST segment elevation myocardial infarctionSIDER
79Surgical failureOFFSIDES
80SweatingSIDER
81SwellingSIDER
82Therapy non-responderOFFSIDES
83Troponin I increasedOFFSIDES
84Troponin TOFFSIDES
85UrticariaSIDER
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