Experimental evidence search

Table 3: Cell death of L929 cells treated with Hydrostatin-AMP2 is 8.08%.

Table 3: Cell death of HaCaT cells treated with Hydrostatin-AMP2 is 5.89%.

Table 3: Cell death of RAW264.7 cells treated with Hydrostatin-AMP2 is 10.81%.

Table 3: Hemolysis of human erythrocytes by Hydrostatin-AMP2 is 4.6%.

After incubation ... the calculated hemolysis ratio of OMV groups was lower than 5% (Figures 5A, B), indicating the negligible hemolysis caused by bioengineered OMVs in vitro.

After incubation ... the calculated hemolysis ratio of OMV groups was lower than 5% (Figures 5A, B).

After incubation ... the calculated hemolysis ratio of OMV groups was lower than 5% (Figures 5A, B).

octopromycin did not show considerable cytotoxic effects on human (HEK293T) or mouse (Raw264.7) cells at concentrations up to 400 μg/mL [24].

octopromycin did not show considerable cytotoxic effects on human (HEK293T) or mouse (Raw264.7) cells at concentrations up to 400 μg/mL [24].

also did not cause hemolysis in mouse red blood cells at high concentrations (<300 µg/mL) [24].

Embryos exposed to different concentrations did not display any visible anomalies. ... peptides from S. amaranthoides do not demonstrate any toxic effect on embryos.

Embryos exposed to different concentrations did not display any visible anomalies. ... peptides from S. amaranthoides do not demonstrate any toxic effect on embryos.

Embryos exposed to different concentrations did not display any visible anomalies. ... peptides from S. amaranthoides do not demonstrate any toxic effect on embryos.

Figure 3A: cell viability of P9 at a lower concentration (6.25 uM) began to decrease significantly (p < 0.05), and the cell viability of 25, 50, 100, and 200 uM also decreased significantly, with extremely significant differences (p < 0.01).

Figure 3B: cell viability began to decrease significantly at low concentration (3.125 uM) of P11 (p < 0.05), showing that this concentration can make cells significantly toxic (p < 0.05). Other concentrations also have significant effects on cell viability (p < 0.05).

Figure 3C: P12 has significant effect on the viability of PC12 cells at 6.25 uM (p < 0.05). But there was no significant difference at other concentrations.

Figure 3D: the cell viability of P21 was significantly reduced at 25 uM (p < 0.05), and the cytotoxic peptide concentration produced at this time was higher than that of other peptides, and the cytotoxicity of P21 itself was lower.

Figure 5: P21 polypeptide has a good inhibitory effect on the PC12 cytotoxicity caused by the aggregation of Aβ1-42 at a low concentration ratio (1:0.25 and 1:0.5). After the concentration ratio of P21 reached 1:1, with the increase of P21 concentration (1:2, 1:4), cell viability continued to increase, reaching the maximum at 1:4, which was close to the normal level.

Section 2.8.1: None of the concentrations of FNZ produced hemolytic activity on erythrocytes; no damage to mouse red blood cells (MRBCs) with FNZ in all scope-effective concentrations.

Section 2.8.1: FNZ showed low cytotoxicity (88.56% survival) toward mouse macrophages RAW264.7 cells at 128 μg/mL