Primary experimental recordNegative / threshold

PMC10126514::ACT000306

Evidence text

Paper-level observation

Figure 3A: cell viability of P9 at a lower concentration (6.25 uM) began to decrease significantly (p < 0.05), and the cell viability of 25, 50, 100, and 200 uM also decreased significantly, with extremely significant differences (p < 0.01).

textConfidence: medium

Assay observation

Activity

Toxicity

Subtype

Cytotoxic

Measure

cell_viability

Comparator

Raw observation

cell viability decreased significantly at 6.25 uM (p<0.05), and at 25, 50, 100, 200 uM (p<0.01)

Normalized measurement

<0.05

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Rattus norvegicus

Assay method

Not reported by source

Sequence

YVRHHHYVRHHH

Standardization

ready simple

Source publication

The interaction of peptide inhibitors and Aβ protein: Binding mode analysis, inhibition of the formation of Aβ aggregates, and then exert neuroprotective effects.

Frontiers in Aging Neuroscience · 2023

DOI 10.3389/fnagi.2023.1139418 PMC10126514

Parent mention

Related peptide identities

PEPDIA-PLP-003360

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.