Primary experimental recordNegative / threshold

PMC10126514::ACT000307

P11

Evidence text

Paper-level observation

Figure 3B: cell viability began to decrease significantly at low concentration (3.125 uM) of P11 (p < 0.05), showing that this concentration can make cells significantly toxic (p < 0.05). Other concentrations also have significant effects on cell viability (p < 0.05).

textConfidence: medium

Assay observation

Activity

Toxicity

Subtype

Cytotoxic

Measure

cell_viability

Comparator

Raw observation

cell viability decreased significantly at 3.125 uM (p<0.05) and other concentrations (p<0.05)

Normalized measurement

<0.05

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Rattus norvegicus

Assay method

Not reported by source

Sequence

YVRHSVYVRHSV

Standardization

ready simple

Source publication

The interaction of peptide inhibitors and Aβ protein: Binding mode analysis, inhibition of the formation of Aβ aggregates, and then exert neuroprotective effects.

Frontiers in Aging Neuroscience · 2023

DOI 10.3389/fnagi.2023.1139418 PMC10126514

Parent mention

Related peptide identities

PEPDIA-PLP-003362

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.