AptaDB: Result

Interaction ID: 1117

Aptamer sequence: CGATGGAGGACCTCCGGTTTACCGTGTCGTTTTACTCTTG

Target unique ID: Other-53

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1064	Apt_NDV03	Other	Newcastle disease virus (NDV)	78.1 nM	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2	32790805

Aptamer Sequence:	CGATGGAGGACCTCCGGTTTACCGTGTCGTTTTACTCTTG
The optimal secondary structure in dot-bracket notation:	..((((.(((((...))))).))))...............
The centroid secondary structure in dot-bracket notation:	....((..((((...))))..)).................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1064	Description	Apt_NDV03
Aptamer chemistry	DNA	Length	40 nt
GC content	52.5%	Molecular weight	12,275.86 Da
Molarity of 1 μg/μl solution	81.46 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	CGATGGAGGACCTCCGGTTTACCGTGTCGTTTTACTCTTG
Applications	Detection of NDV in poultry samples

Type	Detail	Type	Detail
Target ID	Other-53	Name	Newcastle disease virus (NDV)

	Interaction ID	1117
	Target type	Other
	Target unique ID	Other-53
	Activity	78.1 nM
	Binding Conditions/Buffer	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2
	Assay	Highly specific aptamers against NDV
	PubMed ID	32790805

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_961	DNA	CTAGTGGGGACCTTCCAGGGTAACTGCTCGCATTCTCCAT	60.00%
Apta_35	DNA	TGGGTGGCCTCCCGTTTATTCGAGATTTGGTTGAATTTGT	57.50%
Apta_1176	DNA	AGTATGATATCGGTGTTTATGGTGTCTGTCTTCATACT	55.00%
Apta_1210	DNA	GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG	55.00%
Apta_1215	DNA	GTCGAATCAGCACCTCTGCATAGGTTACGTTTATACTGCG	55.00%
Apta_1177	DNA	TCCTACTCGTGATATCGGTGTTTATGGTGTCTGTCTTCATGTAGGA	54.35%
Apta_484	DNA	CAGGGAGGGACAGGGCGGGAATTTGTATGATGGTTCGTTTGCTCG	53.33%
Apta_748	DNA	AGCTTGAGGGTGGGCGGGTGGACGCGGTAGTGGTATATAGGTCGG	53.33%
Apta_263	DNA	AGAGGGGAGGGTCGGGTATCGGCGTGTTCGGGGGATCTGC	52.50%
Apta_393	DNA	AGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT	52.50%
Apta_691	DNA	CGACGCGCGTTGGTGGTGGATGGTGTGTTACACGTGTTGT	52.50%
Apta_1059	DNA	TCGTGACGCCGTGCAGTTACCGATACGAGCCTCGTTTTG	52.50%
Apta_1138	DNA	GCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	52.50%
Apta_1241	DNA	GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC	52.50%
Apta_1254	DNA	GGCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	52.50%
Apta_1087	DNA	CTTACGACTCAGGCATTTTGCCGGGTAACGAAGTTACTGTCGTAAG	52.17%
Apta_335	DNA	ACCGGGCGTACACCGTCGCGGCACATGTCTGAATGCGTTTAGTCTCTGTG	52.00%
Apta_595	DNA	AGCGAGGGCGGTGTCCAACAGCGGTTTTTTCACGAGGAGGTTGGCGGTGG	52.00%
Apta_1046	DNA	TCGCATGGAGGGCAGAGCCGCCTGCCGGGATCCGGCCCTCTTGGGCGGGC	52.00%
Apta_650	DNA	GCACACCGATGGCGGTCCTGTTTAGGGGGTGTGCGTGGGGAGGTGCGGTTGC	51.92%

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