AptaDB: Result

Interaction ID: 1115

Aptamer sequence: GGGGTCTTGCAGGTCCCGTAGGAGGGGCCATTGGAGTGGGG

Target unique ID: Other-53

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1062	Apt_NDV01	Other	Newcastle disease virus (NDV)	31 nM	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2	32790805

Aptamer Sequence:	GGGGTCTTGCAGGTCCCGTAGGAGGGGCCATTGGAGTGGGG
The optimal secondary structure in dot-bracket notation:	....(((....((((((......))))))...)))......
The centroid secondary structure in dot-bracket notation:	...........((((((......))))))............

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1062	Description	Apt_NDV01
Aptamer chemistry	DNA	Length	41 nt
GC content	68.3%	Molecular weight	12,875.21 Da
Molarity of 1 μg/μl solution	77.67 μM	Number of G-quadruplexes	2
G-Score	19	Function	Target detection
Sequence	GGGGTCTTGCAGGTCCCGTAGGAGGGGCCATTGGAGTGGGG
Applications	Detection of NDV in poultry samples

Type	Detail	Type	Detail
Target ID	Other-53	Name	Newcastle disease virus (NDV)

	Interaction ID	1115
	Target type	Other
	Target unique ID	Other-53
	Activity	31 nM
	Binding Conditions/Buffer	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2
	Assay	Highly specific aptamers against NDV
	PubMed ID	32790805

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_1195	DNA	GGGGTTGGGGGGAGGCGGGGAATGGGGG	58.54%
Apta_46	DNA	CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTT	56.10%
Apta_264	DNA	GGCGTTGTCGGGCGCAGGTGTAGGCCTCGTGGTGGTGGGT	56.10%
Apta_693	DNA	CGAGTTGAGCCGGGCGCGGTACGGGTACTGGTATGTGTGG	56.10%
Apta_806	DNA	GGTTGGATGTAAGGTTGGAGGGGGG	56.10%
Apta_830	DNA	GACGGTGGCAGGGAAAGGGGTCGGGCATATGGCGGAGGGG	56.10%
Apta_1193	DNA	GGGTTGGAGGTGGAGGGGAGTTGAGG	56.10%
Apta_143	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG	55.10%
Apta_144	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAG	54.55%
Apta_596	DNA	GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG	54.00%
Apta_941	DNA	CGGGTGCCTTAAAGTGTAGGTGGGAGGGGGATGATTATGTACGATCAAGT	54.00%
Apta_650	DNA	GCACACCGATGGCGGTCCTGTTTAGGGGGTGTGCGTGGGGAGGTGCGGTTGC	53.85%
Apta_10	DNA	GGGGGGGGTGGCTGGGCGGGGTGGG	53.66%
Apta_493	DNA	GGGGTGGTGGGTTCTTTTTGTGGTATTGGTGTGGGGGGCA	53.66%
Apta_673	DNA	GCAGTCCTAGATCGGGTGTGGCTGGCTTGG	53.66%
Apta_682	DNA	CCTTGTAGATCGGGTGTGGTTTGGCGTAGG	53.66%
Apta_808	DNA	GGGTCTTCCTGGACTGTCGAAAATTCAGTATCGGGAGG	53.66%
Apta_857	DNA	GCTATGGGTGGTCTGGTTGGGATTGGCCCCGGGAGCTGGC	53.66%
Apta_1097	DNA	AGGCCCTACACGCCTTTTAGCGAGGGCGTTCCGTGGAGGA	53.66%
Apta_1205	DNA	GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG	53.66%

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