Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_855 | S-PS8.4 | Other | IVB pil operon of S. enterica serovar Typhi | 7.2 nM | 25 mM Tris-HCl, 50 mM KCl, 200 mM NaCl, 0.2 mM EDTA, 5% [vol/vol] glycerol, 0.5 mM DTT | 16189080 |
Structure information of aptamer
| Aptamer Sequence: | UCACUGUUAUCCGAUAGCAGCGCGGGAUGA |
| The optimal secondary structure in dot-bracket notation: | ...(((((((...))))))).......... |
| The centroid secondary structure in dot-bracket notation: | ...((((((.....)))))).......... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_855 | Description | S-PS8.4 |
| Aptamer chemistry | RNA | Length | 30 nt |
| GC content | 53.3% | Molecular weight | 9,628.76 Da |
| Molarity of 1 μg/μl solution | 103.86 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | UCACUGUUAUCCGAUAGCAGCGCGGGAUGA | ||
| Applications | Detection of salmonella enterica | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-4 | Name | IVB pil operon of S. enterica serovar Typhi |
Activity data
 |
Interaction ID | 941 |
| Target type | Other | |
| Target unique ID | Other-4 | |
| Activity | 7.2 nM | |
| Binding Conditions/Buffer | 25 mM Tris-HCl, 50 mM KCl, 200 mM NaCl, 0.2 mM EDTA, 5% [vol/vol] glycerol, 0.5 mM DTT |
|
| Assay | Inhibition of bacterial adhesion and invasion by the RNA pools obtained at various intervals during the SELEX procedure |
|
| PubMed ID | 16189080 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_85 | RNA | UGCGACUGUUAUAACCUAACAGCGACGUAAAGAUA | |
| Apta_319 | RNA | ACCCUGAUGGUAGACGCCGGGGUG | |
| Apta_313 | RNA | UGCCCUGCCCUCACCCGUUAGCCUGAGCGCCCCGCA | |
| Apta_97 | RNA | UUGUCGUCUUCUCCAGUUAGUCAACGAACUUGUGU | |
| Apta_849 | RNA | UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC | |
| Apta_924 | RNA | GCCUUUUCGGGAUACGCGGAGGGUGGGCAA | |
| Apta_1140 | RNA | UAGUGUGAGAGCCGUGAGUGAAAGGCCGCGACAAAGAUCGGA | |
| Apta_96 | RNA | UCGCUAAUUAUAGGCGGAGUGCGACGUUAUAAAUA | |
| Apta_1 | RNA | ACGAAGCUUGAUCCCGUUUGCCGGUCGAUCGCUUCGA | |
| Apta_324 | DNA | CAAACAATCAAACAGCAGTGGGGTG | |
| Apta_324 | DNA | CAAACAATCAAACAGCAGTGGGGTG | |
| Apta_955 | RNA | ACGUAUCCCUUUUCGCGUA | |
| Apta_956 | RNA | ACGUUUCCCUUUUCGCGUA | |
| Apta_51 | RNA | GCCUUAGUAACGUGCUUUGAUGUCGAUUCGACAGGAGGC | |
| Apta_237 | RNA | UUCAACGCUGUGAAGGGCUUAUACGAGCGGAUUACCC | |
| Apta_86 | RNA | GAAACGACUCGACAACCUCGAGCGACGUGAAUCAU | |
| Apta_87 | RNA | UACCGACUAGCAAAACCUGCUGGCGACGUUUAGAU | |
| Apta_89 | RNA | AAUAACCUUAAUGCGACGUUGGUUCGUCAACAUGG | |
| Apta_93 | RNA | CUCCGCUAUCUAACGUAUGAUAGAAUGGAUGACUA | |
| Apta_588 | RNA | CCGGUGCGCAUAACCACCUCAGUGCGAGCAAGGAA |
DEV TOOL
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