Aptamer-target interaction descriptor
Aptamer-target interaction information
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1145 | 21-mer aptamer | Molecule | Aflatoxin M1 | N/A | N/A | 12238815 |
Structure information of aptamer
| Aptamer Sequence: | ACTGCTAGAGATTTTCCACAT |
| The optimal secondary structure in dot-bracket notation: | ..................... |
| The centroid secondary structure in dot-bracket notation: | ..................... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1145 | Description | 21-mer aptamer |
| Aptamer chemistry | DNA | Length | 21 nt |
| GC content | 38.1% | Molecular weight | 6,380.16 Da |
| Molarity of 1 μg/μl solution | 156.74 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | ACTGCTAGAGATTTTCCACAT | ||
| Applications | Detection of aflflatoxin M1 | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 15558498 | Molecular name | Aflatoxin M1 |
| Molecular formula | C17H12O7 | Molecular weight | 328.27 |
| IUPAC name | (3R,7R)-3-hydroxy-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione | InChIKey | MJBWDEQAUQTVKK-IAGOWNOFSA-N |
| LogP | 1.38 | Topological polar surface area | 95.2 |
| Hydrogen bond acceptor | 7 | Hydrogen bond donor | 1 |
Synonym(s): AFLATOXIN M1; 6795-23-9; 4-Hydroxyaflatoxin B1; UNII-I3020O28I3; I3020O28I3; (3R,7R)-3-hydroxy-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione; (6aR,9aR)-9a-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; 25325-49-9; Aflatoxin M1 0.5 microg/mL in Acetonitrile; CCRIS 15; EINECS 229-865-4; AFLATOXINM1; CHEBI:78576; DTXSID40891797; ZINC402666; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-; EX-A5477; MFCD00871812; Aflatoxin M1, from Aspergillus flavus; C16756; A937070; Q26998369; Aflatoxin M1 solution, 0.5 mug/mL in acetonitrile, analytical standard; (3R,7R)-3-hydroxy-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0^{2,9}.0^{3,7}.0^{13,17}]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione; (6AR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione; (7R)-3-Hydroxy-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione; Aflatoxin M1 solution, certified reference material, 10 mug/mL in acetonitrile, ampule of 1 mL; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-; Rel-(6aR,9aR)-9a-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
Activity data
|
No relevant experimental diagram |
Interaction ID | 1205 |
| Target type | Molecule | |
| Target unique ID | 15558498 | |
| Activity | N/A | |
| Binding Conditions/Buffer | N/A |
|
| Assay | N/A |
|
| PubMed ID | 12238815 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_185 | DNA | ACCAAGGCTTTAGGTCTGAGATCTCCCAAT | |
| Apta_915 | DNA | ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT | |
| Apta_199 | DNA | TAGGTCTGAGATCTCGGAAT | |
| Apta_201 | DNA | CTGAGATCTCGGAAT | |
| Apta_325 | DNA | TACTGCATGCACACCACTTCAACTA | |
| Apta_330 | DNA | GCTGGGTAAATAGATGATTCCCGGC | |
| Apta_325 | DNA | TACTGCATGCACACCACTTCAACTA | |
| Apta_1282 | DNA | TCCTCTCACACATCTTATCCCCTAGGG | |
| Apta_187 | DNA | ACCAACCCTTTACCTCTGAGATCTCCCAAT | |
| Apta_1147 | DNA | GGGGACTAGAGGACTTGTGCGGCC | |
| Apta_407 | DNA | GTGAATTGCGTTGAATTATGTTTTTTCAGTCATCACT | |
| Apta_423 | DNA | TGGGAGCTGATGTCGCATGGGTTTTGATCACATGA | |
| Apta_75 | DNA | CACTGGTAGGTTGGTGTGGTTGGGGCCAGTG | |
| Apta_434 | DNA | ACACGACGGGAATACTGACTCTCCCCCATGT | |
| Apta_227 | DNA | ACGCGCCTATGGTGCATCGCATGCCGACC | |
| Apta_66 | DNA | TACCGTGGTAGGGAAGGTTGGAGTGTA | |
| Apta_202 | DNA | AAGGCTTTAGGTCTGAGATCTCGGAAT | |
| Apta_197 | DNA | GGCTTTAGGTCTGAGATCTCGGAAT | |
| Apta_200 | DNA | AGGAAGGCTTTAGGT | |
| Apta_210 | DNA | AGGTTGGTTGGTTGGAAT |
DEV TOOL
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