MetaADEDB 2.0 @ LMMD
Chlorothiazide
(JBMKAUGHUNFTOL-UHFFFAOYSA-N)
Structure
SMILES
Clc1cc2NC=NS(=O)(=O)c2cc1S(=O)(=O)N
Type(s)
Approved; Vet_approved
ATC code(s)
C03AA04; C03AB04; C03AH01; G01AE10
Molecular Formula:
C7H6ClN3O4S2
Molecular Weight:
295.723
Log P:
2.5654
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
135.45
CAS Number(s):
58-94-6
Synonym(s)
1.
Chlorothiazide
External Link(s)
MeSHD002740
PubChem Compound2720
BindingDB39351
ChEBI3640
CHEMBLCHEMBL3392493
CHEMBL842
DrugBankDB00880
DrugCentral609
IUPHAR/BPS Guide to PHARMACOLOGY4835
KEGGcpd:C07461
dr:D00519
Therapeutic Target DatabaseD0M9WM
ZINC3872055
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DehydrationFAERS: 1OFFSIDES
US FAERS
2General symptomFAERS: 1OFFSIDES
US FAERS
3Mental retardation severity unspecifiedFAERS: 1US FAERS
4Product use in unapproved indicationFAERS: 1US FAERS
5Urinary RetentionFAERS: 1US FAERS
6Abdominal InfectionOFFSIDES
7Acid refluxOFFSIDES
8AcidosisOFFSIDES
9Acute graft versus host disease in liverOFFSIDES
10Acute kidney injury5738352CTD
11AgitationSIDER
12AgranulocytosisSIDER
13AlbuminuriaCanada Vigilance: 1Canada Vigilance
14AlopeciaSIDER
15AlveolitisOFFSIDES
16Anal FissureOFFSIDES
17Anaphylactic shockSIDER
18AnhedoniaOFFSIDES
19AnhidrosisOFFSIDES
20AnorexiaOFFSIDES
SIDER
21AnxietyOFFSIDES
22Aortic AneurysmOFFSIDES
23ArteriosclerosisOFFSIDES
24AstheniaSIDER
25AtelectasisOFFSIDES
26Azotemia5738352CTD
27BedriddenOFFSIDES
28Blood albumin decreasedOFFSIDES
29Blood creatine increasedOFFSIDES
30Blood creatine phosphokinase increasedOFFSIDES
31Blood creatinine increasedOFFSIDES
32Blood glucose abnormalOFFSIDES
33Blood pH increasedOFFSIDES
34Blood sodiumOFFSIDES
35Blood urine presentOFFSIDES
36Bone density decreasedOFFSIDES
37Bone painOFFSIDES
38BronchopneumoniaOFFSIDES
39Capillary Leak SyndromeOFFSIDES
40Cerebral dysgenesisOFFSIDES
41Cerebral ventricle dilatationOFFSIDES
42Choking sensationOFFSIDES
43Chronic Obstructive Airway DiseaseOFFSIDES
44Chronic sinusitisOFFSIDES
45ChylothoraxOFFSIDES
46Colonic Pseudo-ObstructionOFFSIDES
47Congenital pulmonary hypertensionOFFSIDES
48Congenital tricuspid valve incompetenceOFFSIDES
49ConstipationSIDER
50Cor pulmonaleOFFSIDES
51CraniotabesOFFSIDES
52Death of childOFFSIDES
53DermatitisSIDER
54Diabetes Insipidus4727756CTD
55Diaphragmatic HerniaOFFSIDES
56DiarrheaOFFSIDES
57Diastolic dysfunctionOFFSIDES
58DizzinessSIDER
59Drug exposure during pregnancyOFFSIDES
60DysmorphismOFFSIDES
61DysuriaOFFSIDES
62Echocardiogram abnormalOFFSIDES
63Economic problemOFFSIDES
64EczemaCanada Vigilance: 1Canada Vigilance
65Electrolyte imbalanceSIDER
66Electromechanical dissociationOFFSIDES
67EndarterectomyOFFSIDES
68Engraftment syndromeOFFSIDES
69EnteritisOFFSIDES
70Enterococcal infectionOFFSIDES
71EnterocolitisOFFSIDES
72Eosinophilic myocarditisOFFSIDES
73Epigastric discomfortSIDER
74Erectile dysfunctionSIDER
75Erythema InfectiosumOFFSIDES
76Erythema MultiformeSIDER
77ErythemaCanada Vigilance: 1Canada Vigilance
SIDER
78Febrile NeutropeniaOFFSIDES
79Fluid overloadOFFSIDES
80FormicationOFFSIDES
81Gastric irritationSIDER
82Gastrointestinal hypomotilityOFFSIDES
83General physical health deteriorationOFFSIDES
84GlaucomaOFFSIDES
85GlycosuriaSIDER
86GoutCanada Vigilance: 1Canada Vigilance
OFFSIDES
87HeadacheSIDER
88Hepatic InfarctionOFFSIDES
89Hepatic necrosisOFFSIDES
90HepatitisOFFSIDES
91HepatosplenomegalyOFFSIDES
92HydronephrosisOFFSIDES
93Hypercalcemia2706898
5305802		CTD
94Hypercalciuria1324751
6600835		CTD
95HypersensitivitySIDER
96Hypokalemia5668173CTD
97Hyponatremia6635723CTD
98HypotensionSIDER
99HypoxiaOFFSIDES
100Incorrect dose administeredOFFSIDES
101Iron OverloadOFFSIDES
102Kidney Calculi1324751
7110808		CTD
103Kidney FailureOFFSIDES
104LethargyOFFSIDES
105Leukopenia neonatalOFFSIDES
106LeukopeniaSIDER
107Lung InjuryOFFSIDES
108Mental status changesOFFSIDES
109Metabolic acidosisOFFSIDES
110Multiple MyelomaOFFSIDES
111Muscle necrosisOFFSIDES
112Muscle strainOFFSIDES
113NauseaSIDER
114Nervous tensionOFFSIDES
115Neutrophil count decreasedOFFSIDES
116Noonan SyndromeOFFSIDES
117ObstructionOFFSIDES
118OliguriaOFFSIDES
119Optic Disc EdemaOFFSIDES
120OrthopneaOFFSIDES
121OsteopeniaOFFSIDES
122PainOFFSIDES
123Pancreas lipomatosisOFFSIDES
124PancreatitisSIDER
125Paresis5668173CTD
126Pericardial effusionOFFSIDES
127PneumoniaSIDER
128Polyuria656782
4360856		CTD
129Portal Vein ThrombosisOFFSIDES
130PosturingOFFSIDES
131PruritusCanada Vigilance: 2Canada Vigilance
132Pulmonary HypertensionOFFSIDES
133Pulmonary Valve StenosisOFFSIDES
134Pulmonary malformationOFFSIDES
135PurpuraCanada Vigilance: 2Canada Vigilance
SIDER
136RalesOFFSIDES
137Respiratory FailureOFFSIDES
138Respiratory distressSIDER
139Retinal vascular occlusionOFFSIDES
140RhabdomyolysisOFFSIDES
141Right Ventricular DysfunctionOFFSIDES
142Risus sardonicusOFFSIDES
143Septic ShockOFFSIDES
144Sputum culture positiveOFFSIDES
145Status EpilepticusOFFSIDES
146Stevens-Johnson Syndrome25811541CTD
OFFSIDES
SIDER
147StressOFFSIDES
148Supraventricular tachycardiaOFFSIDES
149ThrombocytopeniaSIDER
150Tinea PedisOFFSIDES
151Toxic Epidermal NecrolysisSIDER
152Trisomy 21OFFSIDES
153Unresponsive to stimuliOFFSIDES
154Urinary tract infection pseudomonalOFFSIDES
155UrticariaSIDER
156Vascular purpuraSIDER
157VasculitisSIDER
158Venoocclusive diseaseOFFSIDES
159Venous Thrombosis4301397CTD
160VertebroplastyOFFSIDES
161VertigoSIDER
162VomitingSIDER
163Wrong technique in drug usage processOFFSIDES
164XanthopsiaSIDER
165jaundiceSIDER
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