Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 999
Aptamer sequence: ATACGGGAGCCAACACCAATTCCGCCAAAGTCTGCTAATAAACGGACGCCGGGGAGAGCAGGTGTGACGGAT
Target unique ID: Other-27
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_908 | seqU4 | Other | β-Casomorphin-7 (BCM-7) | 23.11 nM | 20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0 | 25712869 |
Structure information of aptamer
| Aptamer Sequence: | ATACGGGAGCCAACACCAATTCCGCCAAAGTCTGCTAATAAACGGACGCCGGGGAGAGCAGGTGTGACGGAT |
| The optimal secondary structure in dot-bracket notation: | .........((.(((((..((((.((...(((((........)))))...))))))....)))))...)).. |
| The centroid secondary structure in dot-bracket notation: | .........((.(((((..((((.((...(((((........)))))...))))))....)))))...)).. |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_908 | Description | seqU4 |
| Aptamer chemistry | DNA | Length | 72 nt |
| GC content | 55.6% | Molecular weight | 22,318.32 Da |
| Molarity of 1 μg/μl solution | 44.81 μM | Number of G-quadruplexes | 2 |
| G-Score | 20 | Function | Targeted binding |
| Sequence | ATACGGGAGCCAACACCAATTCCGCCAAAGTCTGCTAATAAACGGACGCCGGGGAGAGCAGGTGTGACGGAT | ||
| Applications | Sensing of β?Casomorphin?7 | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-27 | Name | β-Casomorphin-7 (BCM-7) |
Activity data
 |
Interaction ID | 999 |
| Target type | Other | |
| Target unique ID | Other-27 | |
| Activity | 23.11 nM | |
| Binding Conditions/Buffer | 20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0 |
|
| Assay | ELASA for BCM-7. The extent of displacement of the BCM-7 peroxidase conjugate by BCM-7, BCM-5, BCM-9A1, and BCM-9A2 at fixed concentration |
|
| PubMed ID | 25712869 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_527 | DNA | ATACGGGAGCCAACACCAACAACCTAGATGTTCTGATAACACGAATCGCTTCGAAGAGCAGGTGTGACGGAT | |
| Apta_824 | DNA | ATACGGGAGCCAACACCATCCCTCTTAGGATACAAAGCCAAACTGAGCCCGTGCAGAGCAGGTGTGACGGAT | |
| Apta_528 | DNA | ATACGGGAGCCAACACCACTTGGTTAACCAATCAAACCGGACAACGAAGGGTCCAGAGCAGGTGTGACGGAT | |
| Apta_907 | DNA | ATACGGGAGCCAACACCACAACAAGATAAAGTATCAATCTGGTTGACGGACGTGAGAGCAGGTGTGACGGAT | |
| Apta_1048 | DNA | ATACGGGAGCCAACACCACCTGCGGAAAATCAACAACGACACACGCCACGATTCAGAGCAGGTGTGACGGAT | |
| Apta_526 | DNA | ATACGGGAGCCAACACCAAGTAACACACGCGGACCAGAAATACATCCCCCCGTAGAGCAGGTGTGACGGAT | |
| Apta_896 | DNA | ATACGGGAGCCAACACCATAAGTCTAAAAAACTGGGAGTAAACACAATGTGTATAGAGCAGGTGTGACGGAT | |
| Apta_897 | DNA | ATACGGGAGCCAACACCACTCTTATTTCCGGAAGTGGTTCTTCAACAGAGGAATAGAGCAGGTGTGACGGAT | |
| Apta_898 | DNA | ATACGGGAGCCAACACCAACAAAACTAGCAAATTAGAGCCGTATCGGAGCCTATAGAGCAGGTGTGACGGAT | |
| Apta_904 | DNA | ATACGGGAGCCAACACCAGACGGTAAATAAAGTCAGTATCGAGTACTCTATTCGAGAGCAGGTGTGACGGAT | |
| Apta_954 | DNA | ATACGGGAGCCAACACCAGGACTAACATTATAAGAATTGCGAATAATCATTGGAGAGCAGGTGTGACGGAT | |
| Apta_533 | DNA | ATACGGGAGCCAACACCAAAGTAAGATCATCACCCGGACGCGGACATAATAGGAGAGCAGGTGTGACGGAT | |
| Apta_825 | DNA | ATACGGGAGCCAACACCACCCGTGGCCTTCACCCAGCCAGGGACCCCGTCTCTGAGAGCAGGTGTGACGGAT | |
| Apta_533 | DNA | ATACGGGAGCCAACACCAAAGTAAGATCATCACCCGGACGCGGACATAATAGGAGAGCAGGTGTGACGGAT | |
| Apta_901 | DNA | ATACGGGAGCCAACACCACAAGTTGACTTGGAGGAGGGTCTAACTAGTTCGAGGAGAGCAGGTGTGACGGAT | |
| Apta_902 | DNA | ATACGGGAGCCAACACCACCAACATTATCAGAGTATGTTACTTATAGTGGTGGCAGAGCAGGTGTGACGGAT | |
| Apta_903 | DNA | ATACGGGAGCCAACACCAGACGGTAAATAAAGTCAGTATCGATACTCTATTCGAGAGCAGGTGTGACGGAT | |
| Apta_531 | DNA | ATACGGGAGCCAACACCACATCGACTTACGAATCAACGCGTTTATTATTGGTTCAGAGCAGGTGTGACGGAT | |
| Apta_827 | DNA | ATACGGGAGCCAACACCACCCGTGGCCTTCACCCAGCCAGGGGCCCCGTCTCTGAGAGCAGGTGTGACGGAT | |
| Apta_1049 | DNA | ATACGGGAGCCAACACCATGTACATTGTAGATTTATTTGCCCAAAACCCAAGAAGAGCAGGTGTGACGGAT |
DEV TOOL
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