Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 533
Aptamer sequence: TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA
Target unique ID: 213021
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_510 | S18 | Molecule | Acetamiprid | 4.98 μM | N/A | 21306108 |
Structure information of aptamer
| Aptamer Sequence: | TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA |
| The optimal secondary structure in dot-bracket notation: | .(((((.((..((((((((((...)))))))).)).)).)))))..... |
| The centroid secondary structure in dot-bracket notation: | .(((((.((..((((((((((...)))))))).)).)).)))))..... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_510 | Description | S18 |
| Aptamer chemistry | DNA | Length | 49 nt |
| GC content | 40.8% | Molecular weight | 15,091.70 Da |
| Molarity of 1 μg/μl solution | 66.26 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | TGTAATTTGTCTGCAGCGGTTCTTGATCGCTGACACCATATTATGAAGA | ||
| Applications | Determination of this pesticides in agricultural products and environmental samples | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 213021 | Molecular name | Acetamiprid |
| Molecular formula | C10H11ClN4 | Molecular weight | 222.67 |
| IUPAC name | N-[(6-chloropyridin-3-yl)methyl]-N-cyano-N-methylethanimidamide | InChIKey | WCXDHFDTOYPNIE-UHFFFAOYSA-N |
| LogP | 2.066 | Topological polar surface area | 52.28 |
| Hydrogen bond acceptor | 3 | Hydrogen bond donor | 0 |
Synonym(s): Acetamiprid; 135410-20-7; 160430-64-8; Mospilan; Intruder; (E)-N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide; (E)-acetamiprid; (Z)-acetamiprid; NI 25; UNII-5HL5N372P0; N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; CHEBI:39164; NI-25; Ethanimidamide, N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methyl-, (1E)-; Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-, (E)-; CHEBI:39163; (E)-N-(6-Chloro-3-pyridyl)methyl-N'-cyano-N-methylacetamidine; N-((6-Chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide; 5HL5N372P0; Stonkat; Assail; Piorun; Prize; (1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; Ethanimidamide, N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methyl-,(1E)-; Acetamiprid [ISO]; N-(6-Chloro-3-pyridylmethyl)-N-cyano-N-methylacetamidine; N-[(6-chloro-3-pyridyl)methyl]-N'-cyano-N-methyl-acetamidine; Gazelle SG; Mospilan 20SP; NFK 17; HSDB 7274; ADA 06200; TD 2472; TD 2480; Acetamipride; CCRIS 9238; N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide; TD 2472-01; Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-, (1E)-; Acetamiprid-[d3]; TD-2472; TD-2480; BY 102960; DSSTox_CID_14300; DSSTox_RID_79140; DSSTox_GSID_34300; SCHEMBL26296; CHEMBL265941; CHEMBL3185634; DTXSID0034300; SCHEMBL13448458; CHEBI:39165; DTXSID901015148; HY-B0823; N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide; Tox21_301046; 6325AA; BDBM50486223; Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-; MFCD06201842; ZINC13827890; (1E)-N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide; AKOS015891945; AKOS015964740; AKOS030228384; ZINC256008417; VZ31178; (E)-N(sup 1)-((6-chloro-3-pyridyl)methyl)-N(sup 2)-cyano-N(sup 1)-methylacetamidine; NCGC00163881-01; NCGC00163881-02; NCGC00163881-03; NCGC00254948-01; AS-12113; Acetamiprid 10 microg/mL in Ethyl acetate; DB-042287; CAS-135410-20-7; CS-0012839; FT-0621729; FT-0654861; Acetamiprid, PESTANAL(R), analytical standard; C18507; J10337; 410A207; A810143; Q421598; J-006693; Q27119764; (e)-n1-[(6-chloro-3-pyridyl)methyl]-n2-cyano-n1-methylacetamidine; (1Z)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; (E)-N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide; (E)-N^1^-[(6-Chloropyridin-3-yl)methyl]-N^2^-cyano-N^1^-methylacetamidine
Activity data
 |
Interaction ID | 533 |
| Target type | Molecule | |
| Target unique ID | 213021 | |
| Activity | 4.98 μM | |
| Binding Conditions/Buffer | N/A |
|
| Assay | Specificity and affinity determination for S18 |
|
| PubMed ID | 21306108 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_622 | DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | |
| Apta_570 | DNA | GGCAAGATGTGCCCAGAACAGTTGCTTGTATGGTGGGGAGCGTCCATATTGGCTTAAAC | |
| Apta_144 | DNA | GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAG | |
| Apta_441 | DNA | TGAATCTCGCGCTCGTTGGTACCCTTAAAATAAAGGCATA | |
| Apta_1061 | DNA | TATTTATTGAATGCTGTAATTTCGCCACGCGAAAGTAGG | |
| Apta_37 | DNA | TCTATAAACTCTGTCCGGTTTTATAATAATAACATTTTAC | |
| Apta_42 | DNA | GCTGGTCTCTGCGGGTTGTTGCGCCGCGGCACCCTTGGCA | |
| Apta_181 | DNA | CCGTGTAAGGTTTCAGTGGCTTATCCGAAGTAACCCGAGA | |
| Apta_183 | DNA | TAGCACTGTGCGGCGCGTATTGTTCTAATCTGATTACATT | |
| Apta_621 | DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | |
| Apta_614 | DNA | AATCGCATTACCTTATACCAGCTTATTCAATTACGTCTGCACATACCAGCTTATTCAATT | |
| Apta_1169 | DNA | TTTTTTTTTTTCAGCACCGACCTTGTGCTTTGGGAGTGCTGGTCCAAGGGCGTTAATGGACA | |
| Apta_36 | DNA | GTTAATGGGGGATCTCGCGGCCGTTCTTGTTGCTTATACA | |
| Apta_145 | DNA | GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGA | |
| Apta_273 | DNA | ATAAGCTGAGCATCTTAGATCCCCGTCAAGGGCAGCGTAA | |
| Apta_437 | DNA | TCACAGTCCCGGTGCCGCACTAAAACCCATTGTTGTGCGA | |
| Apta_449 | DNA | CGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCG | |
| Apta_776 | DNA | AGTGGTCGAACTACACATCCTTGAACTGCGGAATTATCTAC | |
| Apta_846 | DNA | GTGCAGACAGCTAGTAGTGGTGACTTTCTGTCCAAATCAAGATAA | |
| Apta_850 | DNA | CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA |
DEV TOOL
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