Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 998
Aptamer sequence: ATACGGGAGCCAACACCACAACAAGATAAAGTATCAATCTGGTTGACGGACGTGAGAGCAGGTGTGACGGAT
Target unique ID: Other-27
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_907 seqU3 Other β-Casomorphin-7 (BCM-7) 21.43 nM 20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0 25712869
Structure information of aptamer
Aptamer Sequence: ATACGGGAGCCAACACCACAACAAGATAAAGTATCAATCTGGTTGACGGACGTGAGAGCAGGTGTGACGGAT
The optimal secondary structure in dot-bracket notation: .........((.(((((.((((.((((.........)))).))))......((....)).)))))...))..
The centroid secondary structure in dot-bracket notation: ............(((((.((((.((((.........)))).))))...............))))).......
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_907 Description seqU3
Aptamer chemistry DNA Length 72 nt
GC content 48.6% Molecular weight 22,380.39 Da
Molarity of 1 μg/μl solution 44.68 μM Number of G-quadruplexes 2
G-Score 17 Function Targeted binding
Sequence ATACGGGAGCCAACACCACAACAAGATAAAGTATCAATCTGGTTGACGGACGTGAGAGCAGGTGTGACGGAT
Applications Sensing of β?Casomorphin?7
Target information
Type Detail Type Detail
Target ID Other-27 Name β-Casomorphin-7 (BCM-7)
Activity data

No relevant experimental diagram

 Interaction ID 998
Target type Other
Target unique ID Other-27
Activity 21.43 nM
Binding Conditions/Buffer

20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0
Assay

N/A
PubMed ID 25712869
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_902 DNA ATACGGGAGCCAACACCACCAACATTATCAGAGTATGTTACTTATAGTGGTGGCAGAGCAGGTGTGACGGAT 75.00%
Apta_528 DNA ATACGGGAGCCAACACCACTTGGTTAACCAATCAAACCGGACAACGAAGGGTCCAGAGCAGGTGTGACGGAT 73.61%
Apta_531 DNA ATACGGGAGCCAACACCACATCGACTTACGAATCAACGCGTTTATTATTGGTTCAGAGCAGGTGTGACGGAT 73.61%
Apta_901 DNA ATACGGGAGCCAACACCACAAGTTGACTTGGAGGAGGGTCTAACTAGTTCGAGGAGAGCAGGTGTGACGGAT 73.61%
Apta_903 DNA ATACGGGAGCCAACACCAGACGGTAAATAAAGTCAGTATCGATACTCTATTCGAGAGCAGGTGTGACGGAT 73.61%
Apta_527 DNA ATACGGGAGCCAACACCAACAACCTAGATGTTCTGATAACACGAATCGCTTCGAAGAGCAGGTGTGACGGAT 72.22%
Apta_533 DNA ATACGGGAGCCAACACCAAAGTAAGATCATCACCCGGACGCGGACATAATAGGAGAGCAGGTGTGACGGAT 72.22%
Apta_898 DNA ATACGGGAGCCAACACCAACAAAACTAGCAAATTAGAGCCGTATCGGAGCCTATAGAGCAGGTGTGACGGAT 72.22%
Apta_533 DNA ATACGGGAGCCAACACCAAAGTAAGATCATCACCCGGACGCGGACATAATAGGAGAGCAGGTGTGACGGAT 72.22%
Apta_904 DNA ATACGGGAGCCAACACCAGACGGTAAATAAAGTCAGTATCGAGTACTCTATTCGAGAGCAGGTGTGACGGAT 72.22%
Apta_908 DNA ATACGGGAGCCAACACCAATTCCGCCAAAGTCTGCTAATAAACGGACGCCGGGGAGAGCAGGTGTGACGGAT 72.22%
Apta_954 DNA ATACGGGAGCCAACACCAGGACTAACATTATAAGAATTGCGAATAATCATTGGAGAGCAGGTGTGACGGAT 72.22%
Apta_1048 DNA ATACGGGAGCCAACACCACCTGCGGAAAATCAACAACGACACACGCCACGATTCAGAGCAGGTGTGACGGAT 72.22%
Apta_824 DNA ATACGGGAGCCAACACCATCCCTCTTAGGATACAAAGCCAAACTGAGCCCGTGCAGAGCAGGTGTGACGGAT 70.83%
Apta_526 DNA ATACGGGAGCCAACACCAAGTAACACACGCGGACCAGAAATACATCCCCCCGTAGAGCAGGTGTGACGGAT 69.44%
Apta_896 DNA ATACGGGAGCCAACACCATAAGTCTAAAAAACTGGGAGTAAACACAATGTGTATAGAGCAGGTGTGACGGAT 68.06%
Apta_897 DNA ATACGGGAGCCAACACCACTCTTATTTCCGGAAGTGGTTCTTCAACAGAGGAATAGAGCAGGTGTGACGGAT 68.06%
Apta_1049 DNA ATACGGGAGCCAACACCATGTACATTGTAGATTTATTTGCCCAAAACCCAAGAAGAGCAGGTGTGACGGAT 68.06%
Apta_825 DNA ATACGGGAGCCAACACCACCCGTGGCCTTCACCCAGCCAGGGACCCCGTCTCTGAGAGCAGGTGTGACGGAT 66.67%
Apta_827 DNA ATACGGGAGCCAACACCACCCGTGGCCTTCACCCAGCCAGGGGCCCCGTCTCTGAGAGCAGGTGTGACGGAT 66.67%

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AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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