Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 460
Aptamer sequence: AGCTCCAGAAGATAAATTACAGGGGCCGGGGTGGCTCAGGCAAGGGGTTGACCTGTCGTAGGGATTGTTTTAACAACTAGGATACTATGACCCC
Target unique ID: Q27102
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_455 AP65_A2 Protein Q27102_TRIVA 153 nM PBS-Tween 29972299
Structure information of aptamer
Aptamer Sequence: AGCTCCAGAAGATAAATTACAGGGGCCGGGGTGGCTCAGGCAAGGGGTTGACCTGTCGTAGGGATTGTTTTAACAACTAGGATACTATGACCCC
The optimal secondary structure in dot-bracket notation: .(((((...............))))).(((....)))......(((((((...((((.(((...((((....))))))).))))...)))))))
The centroid secondary structure in dot-bracket notation: .(((((...............))))).................((((((....((((.(((...((((....))))))).))))....))))))
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_455 Description AP65_A2
Aptamer chemistry DNA Length 94 nt
GC content 51.1% Molecular weight 29,197.69 Da
Molarity of 1 μg/μl solution 34.25 μM Number of G-quadruplexes 3
G-Score 58 Function Aptasensor
Sequence AGCTCCAGAAGATAAATTACAGGGGCCGGGGTGGCTCAGGCAAGGGGTTGACCTGTCGTAGGGATTGTTTTAACAACTAGGATACTATGACCCC
Applications Diagnostic assays for the reliable and rapid detection of T. vaginalis in vaginal swabs
Target information
Type Detail Type Detail
Uniprot ID Q27102 Protein name AP65-3 adhesin
Gene name(s) N/A Organism AP65-3 adhesin
Status unreviewed in uniprot database Length 567
Mass 63,134 Activity regulation N/A
Involvement in disease N/A Catalytic activity N/A
PDB ID(s)
N/A
Function N/A
Activity data
Interaction ID 460
Target type Protein
Target unique ID Q27102
Activity 153 nM
Binding Conditions/Buffer

PBS-Tween
Assay

Affinity dissociation constants KD of the full length aptamer candidates calculated by SPR (ii)
PubMed ID 29972299
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_459 DNA AGCTCCAGAAGATAAATTACAGGGGCGGGGGGGCGGGGGAGGCGGAAGGCCTGCTAAAGTCGTTGTGAGCGAACCAACTAGGATACTATGACCCC 74.74%
Apta_454 DNA AGCTCCAGAAGATAAATTACAGGTGAGGGCGGGCGGGTGGTTGTAATATGATCGAATGGTATATGTGTGTTTGCAACTAGGATACTATGACCCCG 72.63%
Apta_456 DNA AGCTCCAGAAGATAAATTACAGGTGGGTGGGTGGGCGGTGGAATTTAGCGGCGGAGCTCTGTGTGTGTTAGGGCAACTAGGATACTATGACCCC 72.34%
Apta_457 DNA AGCTCCAGAAGATAAATTACAGGGGATCAGTAAGGTTGAGACGGCCTGAATCTATCGTGGAGACCACGCGACGCAACTAGGATACTATGACCCC 70.21%
Apta_458 DNA AGCTCCAGAAGATAAATTACAGGGAGAGTAAACTTTGCAAACACAACAATACCATTCCGGAACGTTCTTAACACAACTAGGATACTATGACCCC 67.02%
Apta_759 DNA GAGGCATACCAGCTTATTATTGGGGCCGGGGCAAGGGGGGGGTACCGTGGTAGGACAGATAGTAAGTGCAATCTGCGAA 55.32%
Apta_887 DNA ACGCTCGGATGCCACTACAGGGGGGTGGTCCTGAGGGTGGTGTGGTTGGTTTGGTTTCCTCATGGACGTGCTGGTGAC 55.32%
Apta_1011 DNA GCTGTGTGACTCCTGCAATGGTAGCGGGTAGGGGAGGGAGGGTGAATGGAGGATGTTCATGGCAGCTGTATCTTGTCTCC 54.26%
Apta_584 DNA GTACCAGCTTATTCAATTACACGGACAGAGGGTAGCGGCTCTGCGCATTGAGTTGCTGCGGGCTGAAGCGCGGTACATGGGAGATAGTATGTTCATCAG 53.54%
Apta_235 DNA AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA 52.13%
Apta_1088 DNA ATCCAGAGTGACGCAGCATCGAGTGGCTTGTTTGTAATGTAGGGTTCCGGTCGTGGGTTGGACACGGTGGCTTAGT 52.13%
Apta_465 DNA AGCTGACACAGCAGGTTGGTGGGGGTGGCTTCCAGTTGGGTTGACAATACGTAGGGACACGAAGTCCAACCACGAGTCGAGCAATCTCGAAAT 51.06%
Apta_490 DNA GGGAGACAAGAATAAACGCTCAAGGGCGTGGTGGGTGGGGTACTAATAATGTGCGTTTGTTCGACAGGAGGCTCACAACAGGC 51.06%
Apta_881 DNA AGCGTCGAATACCACTACAGCCCGCACTCAACCACCGTTCCTTTGTTTAATTTTGCACATCTAATGGAGCTCGTGGTCAG 51.06%
Apta_1099 DNA ATCCATTGCCACTGACTACCAGCCGGGTGGGTGGGGGGGTTTGCTGGTATCGCATTGTGCGAAGTCAGTCGGTCGTTAGT 51.06%
Apta_1178 DNA AGCGTCGAATACCACTACAGGGGATGCGAAGTTCCGCGGTCGAGTATATGATACATCCATCTAATGGAGCTCGTGGTCAG 51.06%
Apta_1182 DNA GAATTCAGTCGGACAGCGTCAGTCGTCCCTTTATGCTTGGTGCTCACCGTCTGAATTTCTTCAGATGGACGAATATCGTCTCCC 51.06%
Apta_626 DNA ATACCAGCTTATTCAATTGGTGGTAGGATGGGCTCGATCGAGGTCTTCAGTCGGCTCGGTTTAGTTTATGTTCTCCTGTAGATAGTAAGTGCAATCT 50.52%
Apta_626 DNA ATACCAGCTTATTCAATTGGTGGTAGGATGGGCTCGATCGAGGTCTTCAGTCGGCTCGGTTTAGTTTATGTTCTCCTGTAGATAGTAAGTGCAATCT 50.52%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 50.00%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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