Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 759
Aptamer sequence: ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT
Target unique ID: 73212
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_694 | N | Molecule | Lead (II) ion | 4 nM | 50 mM HEPES, 500 mM NaCl, 20 uM EDTA (pH 7.0 | 12706559 |
Structure information of aptamer
| Aptamer Sequence: | ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT |
| The optimal secondary structure in dot-bracket notation: | (((((((((((((((((((....)))))))))).(((.....)))..))))))))) |
| The centroid secondary structure in dot-bracket notation: | (((((((((((((((((((....)))))))))).(((.....)))..))))))))) |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_694 | Description | N |
| Aptamer chemistry | DNA | Length | 56 nt |
| GC content | 50.0% | Molecular weight | 17,288.10 Da |
| Molarity of 1 μg/μl solution | 57.84 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT | ||
| Applications | Detection and quantification of lead ions in environmental | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 73212 | Molecular name | Lead (II) ion |
| Molecular formula | Pb+2 | Molecular weight | 207 |
| IUPAC name | lead(2+) | InChIKey | RVPVRDXYQKGNMQ-UHFFFAOYSA-N |
| LogP | -0.381 | Topological polar surface area | 0 |
| Hydrogen bond acceptor | 0 | Hydrogen bond donor | 0 |
Synonym(s): Lead(2+); Lead (II) ion; Lead(2+) ion; Pb2+; Pb(2+); Lead ion; 14280-50-3; Lead(2+)ions; Lead(2+) ions; Lead, ion (Pb2+); Lead-239; Lead, isotope of mass 239; Omaha; 239Pb; PbII; Lead ion (Pb2+); Haro Mix MH-204; CHEBI:49807; DTXSID10872437; MCULE-2373499303; 78896-34-1; Q26840873
Activity data
 |
Interaction ID | 759 |
| Target type | Molecule | |
| Target unique ID | 73212 | |
| Activity | 4 nM | |
| Binding Conditions/Buffer | 50 mM HEPES, 500 mM NaCl, 20 uM EDTA (pH 7.0 |
|
| Assay | Detection of Pb(II) in Lake Michigan water |
|
| PubMed ID | 12706559 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_348 | DNA | ACTTGCTCTGATGCGACAACCTTTTGCCCAGATAGTAAGT | |
| Apta_78 | DNA | ATCTCGACTAGTCATAGGGGGCGCGAACATACGCGGTTGGTGTGGTTGGCTGACAATACTCGT | |
| Apta_449 | DNA | CGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCG | |
| Apta_834 | DNA | CGCAATACCAAAGTGGCGAGAGCGCTGTCTTGAGTGAGTGGTTGG | |
| Apta_451 | DNA | ATACCAGCTTATTCAATTGAGTAAGAGTGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCAATCT | |
| Apta_1102 | DNA | TACGACTCACTATAGGGATCCGTGACTGTACGGGCTCAGTCGTTACTTGAGAGTTGAATTCCCTTTAGTGAGGGTT | |
| Apta_1105 | DNA | TACGACTCACTATAGGGATCCAATGGCACAGCGCCTGGAACGTACTCTGTACCTGGAATTCCCTTTAGTGAGGGTT | |
| Apta_577 | DNA | ACTTCAGTGAGTTGTCCCACGGTCGGCGAGTCGGTGGTAG | |
| Apta_730 | DNA | ACCAAACACAGATGCAACCTGACTTCTAACGTCATTTGGTG | |
| Apta_1061 | DNA | TATTTATTGAATGCTGTAATTTCGCCACGCGAAAGTAGG | |
| Apta_1162 | DNA | AGAGGCTACAGCGATAAGTCGACATTGCTGACCGTACCTAGTAATACGT | |
| Apta_1101 | DNA | CCGTAATACGACTCACTATAGGTATGTGACGCGCGTCAATCGCTGTCCTACCAAGCTTTGCAGAGAGGATCCTT | |
| Apta_349 | DNA | ATACCAGCTTATTCAATTAGACGAGTTTTATTCATTTTCCATGTCGTAGCTTACCGTGAGATAGTAAGTGCAATCT | |
| Apta_698 | DNA | AGCAGCACAGAGGTCAGATGCACTCGGACCCCATTCTCCTTCCATCCCTCATCCGTCCACCCTATGCGTGCTACCGTGAA | |
| Apta_944 | DNA | ATACGACTCACTATTAGGGACAAAGCTGACAACCCTTTCATAATCTAACTACATTTATGTGCTAGACTACTGACTAC | |
| Apta_474 | DNA | CAAAAAGATAGGTGGATTTTTCCCCGGATCGGTTTGTATG | |
| Apta_475 | DNA | CAAAAAGATAGGTGGATTTTTCCCCGGGTCGGTTTGTATG | |
| Apta_476 | DNA | CCTATCTTATTCGTTGCGGACTCCCCGGTCGGTATGTATG | |
| Apta_477 | DNA | CGCGGAAGAATTGCTATGTGTGCCCCGGTTGGTCTGTATA | |
| Apta_622 | DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG |
DEV TOOL
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