Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 626
Aptamer sequence: CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC
Target unique ID: 6036
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_592 | Galactose-bisboronic acid aptamer-sensor | Molecule | D-Galactose | 13 nM | Shinkai's receptor 50 uM with 2% methanol | 25343606 |
Structure information of aptamer
| Aptamer Sequence: | CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC |
| The optimal secondary structure in dot-bracket notation: | .....(((((((((.((..((((((...)))).))..))...))))))))) |
| The centroid secondary structure in dot-bracket notation: | .....(((((((((.((..((((((...)))).))..))...))))))))) |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_592 | Description | Galactose-bisboronic acid aptamer-sensor |
| Aptamer chemistry | DNA | Length | 51 nt |
| GC content | 58.8% | Molecular weight | 15,612.00 Da |
| Molarity of 1 μg/μl solution | 64.05 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Aptasensor |
| Sequence | CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC | ||
| Applications | Recognition of D-Galactose | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| PubChem ID | 6036 | Molecular name | D-Galactose |
| Molecular formula | C6H12O6 | Molecular weight | 180.16 |
| IUPAC name | (3R,4S,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol | InChIKey | WQZGKKKJIJFFOK-SVZMEOIVSA-N |
| LogP | -3.221 | Topological polar surface area | 110.38 |
| Hydrogen bond acceptor | 6 | Hydrogen bond donor | 5 |
Synonym(s): D-Gal; D-Galactopyranose; D-Galactopyranoside; D-Galactose; Gal; Galactopyranose; Galactopyranoside; Galactose; 10257-28-0; (3R,4S,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol; cerebrose; CHEBI:4139; (+)-Galactose; D-Glucose-2-13C; SMR000857326; brain sugar; NSC-8102; D-aGalactopyranose; NCGC00159442-02; EINECS 233-595-2; D-Galactose (9CI); DSSTox_CID_3088; Galactose, D- (8CI); Epitope ID:141794; D-(+)-Galactose Anhydrous; DSSTox_RID_76869; DSSTox_GSID_23088; SCHEMBL38935; MLS001335983; MLS001335984; CHEMBL195923; (3R,4S,5R,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol; BDBM228805; DTXSID001015860; HMS2230N07; NSC 8102; Tox21_111672; MFCD00006969; s3849; AKOS030573864; CCG-266426; CAS-59-23-4; D-Galactose plant origin (ex peach gum); NCGC00166082-01; AS-46931; G0008; C00124; D-Galactose 1000 microg/mL in Methanol:Water; F10950; G-1701; O_FULL_10000000000000_GS_94; Q27106307; (3R,4S,5R,6R)-6-methyloltetrahydropyran-2,3,4,5-tetrol; WURCS=2.0/1,1,0/[a2112h-1x_1-5]/1/; 40825-89-6
Activity data
 |
Interaction ID | 626 |
| Target type | Molecule | |
| Target unique ID | 6036 | |
| Activity | 13 nM | |
| Binding Conditions/Buffer | Shinkai's receptor 50 uM with 2% methanol |
|
| Assay | The response of sensors |
|
| PubMed ID | 25343606 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_593 | DNA | CTCTCGGGACGACAGCCGAGTTGATTCAACAGCCGAGTCGTCCC | |
| Apta_556 | DNA | GGCTCTCGGGACGACATGGATTTTCCATCAACGAAGTGCGTCCGTCCC | |
| Apta_591 | DNA | CTCTCGGGACGACGGCTGGCACGTTTGGTTCAAGAATGTGGGTGTCGTCCC | |
| Apta_697 | DNA | CTCTCGGGACGACGGACGCTAATCTTACAAGGGCGTAGTGTATGTCGTCCC | |
| Apta_721 | DNA | CTCTCGGGACGACCGCGGTAGTCTTAACCTAAAGCGGTGTCAGGTCGTCCC | |
| Apta_722 | DNA | CTCTCGGGACGACGGCCCGATCTCAGAGTAGTCGTCCC | |
| Apta_871 | DNA | CCAACCACACATCCTTCCATCGACATGGACCCACCGTTCC | |
| Apta_873 | DNA | CCACCGAGCCTACCACATGTGACATCCCAGGACATAGCTG | |
| Apta_738 | DNA | ATCGTCTGCTCCGTCCAATACCTGCATATACACTTTGCATGTGGTTTGGTGTGAGGTCGTGC | |
| Apta_737 | DNA | ATCGTCTGCTCCGTCCAATAGTGCATTGAAACTTCTGCATCCTCGTTTGGTGTGAGGTCGTGC | |
| Apta_740 | DNA | ATCGTCTGCTCCGTCCAATAAACCTGCATAATTTATAAGTCTAGACTGCTGCATTTGGTGTGAGGTCGTGC | |
| Apta_922 | DNA | ATCCAGAGTGACGCAGCACACCGTTTGTATTCTGCATTGTTTTGCATTCTACATGGACACGGTGGCTTAGT | |
| Apta_663 | DNA | CACGCACAGAAGACACCTACAGGGCCAGATCACAATCGGTTAGTGAACTCGTACGGCGCG | |
| Apta_306 | DNA | CAAGGTAACCAGTACAAGGTGCTAAACGTAATGGCTTCG | |
| Apta_776 | DNA | AGTGGTCGAACTACACATCCTTGAACTGCGGAATTATCTAC | |
| Apta_985 | DNA | CCAGGAGGACCCTATTCTCGTGTATCGACGAGATCCAGTG | |
| Apta_1022 | DNA | CTCCTTCAACGAAGTGGGTTCCTTCAACGAAGTGGGTCTC | |
| Apta_1126 | DNA | TCGGGCGAGTCGTCTGCGGGCGGATAGACTACGACACCGCATCGTCCTCCC | |
| Apta_524 | DNA | ATCCGTCACACCTGCTCTGGCATTAGTATTCCATAGCCGGCCAAGTCTATGTAGTGGTGTTGGCTCCCGTAT | |
| Apta_509 | DNA | TCGCGCGAGTCGTCTGGGGGACTAGAGGACTTGTGCGGCCCCGCATCGTCCTCCC |
DEV TOOL
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