AptaDB: Result

Interaction ID: 147

Aptamer sequence: GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG

Target unique ID: P02768

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_143	G8	Protein	ALBU_HUMAN	1.50 μM	1X PBS, 137mM [Na+], 2mM [Mg2+]	27084987

Aptamer Sequence:	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG
The optimal secondary structure in dot-bracket notation:	...((((...((((.......)))))))).(((......))).......
The centroid secondary structure in dot-bracket notation:	..........((((.......))))........................

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_143	Description	G8
Aptamer chemistry	DNA	Length	49 nt
GC content	57.1%	Molecular weight	15,517.69 Da
Molarity of 1 μg/μl solution	64.44 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG
Applications	Detection of GHSA

Type	Detail	Type	Detail
Uniprot ID	P02768	Protein name	Albumin
Gene name(s)	ALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341	Organism	Albumin
Status	reviewed in uniprot database	Length	609
Mass	69,367	Activity regulation	N/A
Involvement in disease	Hyperthyroxinemia, familial dysalbuminemic (FDAH)	Catalytic activity	N/A
PDB ID(s)	1AO6;1BJ5;1BKE;1BM0;1E78;1E7A;1E7B;1E7C;1E7E;1E7F;1E7G;1E7H;1E7I;1GNI;1GNJ;1H9Z;1HA2;1HK1;1HK2;1HK3;1HK4;1HK5;1N5U;1O9X;1TF0;1UOR;1YSX;2BX8;2BXA;2BXB;2BXC;2BXD;2BXE;2BXF;2BXG;2BXH;2BXI;2BXK;2BXL;2BXM;2BXN;2BXO;2BXP;2BXQ;2ESG;2I2Z;2I30;2N0X;2VDB;2VUE;2VUF;2XSI;2XVQ;2XVU;2XVV;2XVW;2XW0;2XW1;2YDF;3A73;3B9L;3B9M;3CX9;3JQZ;3JRY;3LU6;3LU7;3LU8;3SQJ;3TDL;3UIV;4BKE;4E99;4EMX;4G03;4G04;4HGK;4HGM;4IW1;4IW2;4K2C;4K71;4L8U;4L9K;4L9Q;4LA0;4LB2;4LB9;4N0F;4N0U;4S1Y;4Z69;5FUO;5GIX;5GIY;5ID7;5IFO;5IJF;5UJB;5VNW;5X52;5YB1;5YOQ;5Z0B;6A7P;6EZQ;6HSC;6JE7;6L4K;6M4R;6M58;6M5D;6M5E;6QIO;6QIP;6R7S;6WUW;6XV0;6YG9;6ZL1;7A9C;7AAE;7AAI;7D6J;7DJN;7DL4;7EEK;7JWN;7QFE;7VR9;
Function	Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable).

No relevant experimental diagram	Interaction ID	147
	Target type	Protein
	Target unique ID	P02768
	Activity	1.50 μM
	Binding Conditions/Buffer	1X PBS, 137mM [Na+], 2mM [Mg2+]
	Assay	N/A
	PubMed ID	27084987

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_144	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAG	89.80%
Apta_145	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGA	79.59%
Apta_146	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCG	69.39%
Apta_1259	DNA	GGCGCGGCATGGTGTGGACTCCAGGCGGTAGGGATGTCGT	63.27%
Apta_596	DNA	GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG	62.00%
Apta_148	DNA	CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGGTGGCGTGG	57.14%
Apta_565	DNA	GCGGGGTTGGGCGGGTGGGTTCGCTGGGCAGGGGGCGAGTG	57.14%
Apta_1205	DNA	GGCAGGTGGTGTTGGTTGGTTGTGCGTGGAGTTGG	57.14%
Apta_1261	DNA	GGGCGGACGCTAGGTGGTGATGCTGTGCTACACGTGTTGT	57.14%
Apta_1035	DNA	ATGCGGATCCCGCGCGGGTCTGAGGAGTGCGCGGTGCCAGTGAGTGCGCGAAGCTTGCGC	56.67%
Apta_41	DNA	CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC	55.10%
Apta_50	DNA	AGTGGCGAGGGGGGTAGGTAAAGTATCCTTAGTGTGTTG	55.10%
Apta_149	DNA	CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGATGGCGTGG	55.10%
Apta_150	DNA	CCGTAGGTTCGGGGCGGAGTGGTCCGGAAGGTGGCGTGG	55.10%
Apta_264	DNA	GGCGTTGTCGGGCGCAGGTGTAGGCCTCGTGGTGGTGGGT	55.10%
Apta_831	DNA	CCGCCCAGCGGGGGTAGGGCCGGACGTAGGAGGAGCTGCG	55.10%
Apta_858	DNA	GGCTTCAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACG	55.10%
Apta_963	DNA	TGGCGCTGCCCCTAGTCTCCGGCTGATAGCTGCTTCTTGG	55.10%
Apta_986	DNA	CGTGTATCCCCTGTGTGTTTGTACTCGGCTACTGTATCCG	55.10%
Apta_1014	DNA	TGGGGGTTGGGTGGATAGGCTGGCGTCGGGGCAGGTCAGT	55.10%

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