AptaDB: Result

Interaction ID: 499

Aptamer sequence: GGGGTGGTGGGTTCTTTTTGTGGTATTGGTGTGGGGGGCA

Target unique ID: Q8VA04

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_493	N	Protein	Q8VA04_9VIRU	55 nM	PBS-T (10 mM Na2HPO4, 2 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, and 0.05%Triton-X; pH 7.5) with added 0.1 μg/ml poly-dIdC and 1 μg/ml BSA	20624933

Aptamer Sequence:	GGGGTGGTGGGTTCTTTTTGTGGTATTGGTGTGGGGGGCA
The optimal secondary structure in dot-bracket notation:	..........(((((((...............))))))).
The centroid secondary structure in dot-bracket notation:	..........(((((((...............))))))).

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_493	Description	N
Aptamer chemistry	DNA	Length	40 nt
GC content	57.5%	Molecular weight	12,619.04 Da
Molarity of 1 μg/μl solution	79.25 μM	Number of G-quadruplexes	3
G-Score	50	Function	Targeted binding
Sequence	GGGGTGGTGGGTTCTTTTTGTGGTATTGGTGTGGGGGGCA
Applications	Bound to ASPV

Type	Detail	Type	Detail
Uniprot ID	Q8VA04	Protein name	Capsid protein (Coat protein)
Gene name(s)	N/A	Organism	Capsid protein (Coat protein)
Status	unreviewed in uniprot database	Length	396
Mass	42,575	Activity regulation	N/A
Involvement in disease	N/A	Catalytic activity	N/A
PDB ID(s)	N/A
Function	N/A

No relevant experimental diagram	Interaction ID	499
	Target type	Protein
	Target unique ID	Q8VA04
	Activity	55 nM
	Binding Conditions/Buffer	PBS-T (10 mM Na2HPO4, 2 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, and 0.05%Triton-X; pH 7.5) with added 0.1 μg/ml poly-dIdC and 1 μg/ml BSA
	Assay	N/A
	PubMed ID	20624933

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_879	DNA	GGGGGGGTGAGACATCGGGCATGTTCATGGGTGGGGGGTA	62.50%
Apta_1247	DNA	GGTGGTTGCTGTTGTTTGTGGTTGGTGTGC	62.50%
Apta_752	DNA	GCTATCTTATGGAAATTTCGTGTAGGGTTTGGTGTGGCGGGGCTA	62.22%
Apta_596	DNA	GGTGGCTGTTGGTCGAGGCTTATTAGTGTAGTCAATGGAGGCAGGCGACG	58.00%
Apta_46	DNA	CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTT	57.50%
Apta_267	DNA	GAGTGCGTAATGGTACGATTTGGGAAGTGGCTTGGGGTGG	57.50%
Apta_350	DNA	GGTGGTGGTGGTTGTGGTGGTGGTGG	57.50%
Apta_1188	DNA	CGGGCGGGGCGTGGGGTGTTGGAGTGGAGGGCGGGGCGGC	57.50%
Apta_1210	DNA	GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG	57.50%
Apta_1240	DNA	GGAGTAGTGGGGATTGTGGTGTATGTTGTC	57.50%
Apta_1243	DNA	GGTGTTGTTGTTGGCTAGTTTGTTGTGGGC	57.50%
Apta_1186	DNA	AGGGGGTTTTGGTGGGGGGGGCTGGGTTGTCTTGGGGGTGGGCT	56.82%
Apta_1185	DNA	CAGGGGGTTTTGGTGGGGGGGGCTGGGTTGTCTTGGGGGTGGGCT	55.56%
Apta_70	DNA	AGGTCGTAGGTTGGTGTGGTTGGGGCGACCT	55.00%
Apta_71	DNA	GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC	55.00%
Apta_73	DNA	GGGGAGTAGGTTGGTGTGGTTGGGGCTCCCC	55.00%
Apta_77	DNA	GGTGTGGGCGACATGGGGGTTGGTGGTGTAGGAGCGCCAT	55.00%
Apta_145	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGA	55.00%
Apta_146	DNA	GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCG	55.00%
Apta_264	DNA	GGCGTTGTCGGGCGCAGGTGTAGGCCTCGTGGTGGTGGGT	55.00%

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