AptaDB: Result

Interaction ID: 267

Aptamer sequence: ACGGACTCGCAAAAGGTGGAACAGGAGTGGGCCCCGCGGC

Target unique ID: P08637

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_262	CLN0118	Protein	FCG3A_HUMAN	31 nM	DPBS with 0.05% BSA	21531729

Aptamer Sequence:	ACGGACTCGCAAAAGGTGGAACAGGAGTGGGCCCCGCGGC
The optimal secondary structure in dot-bracket notation:	......((((....((.((..((....))..)))))))).
The centroid secondary structure in dot-bracket notation:	.......(((....((.((..((....))..)))))))..

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_262	Description	CLN0118
Aptamer chemistry	DNA	Length	40 nt
GC content	67.5%	Molecular weight	12,670.92 Da
Molarity of 1 μg/μl solution	78.92 μM	Number of G-quadruplexes	2
G-Score	19	Function	Targeted binding
Sequence	ACGGACTCGCAAAAGGTGGAACAGGAGTGGGCCCCGCGGC
Applications	Binding to target proteins

Type	Detail	Type	Detail
Uniprot ID	P08637	Protein name	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Gene name(s)	FCGR3A CD16A FCG3 FCGR3 IGFR3	Organism	Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
Status	reviewed in uniprot database	Length	254
Mass	29,089	Activity regulation	N/A
Involvement in disease	Immunodeficiency 20 (IMD20)	Catalytic activity	N/A
PDB ID(s)	3AY4;3SGJ;3SGK;3WN5;5BW7;5D6D;5ML9;5MN2;5VU0;5XJE;5XJF;5YC5;7SEG;
Function	Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).

No relevant experimental diagram	Interaction ID	267
	Target type	Protein
	Target unique ID	P08637
	Activity	31 nM
	Binding Conditions/Buffer	DPBS with 0.05% BSA
	Assay	N/A
	PubMed ID	21531729

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_261	DNA	TAAACCCCAAAACAGTGCAACTAGGTGTAGGTCCCGTGGT	62.50%
Apta_706	DNA	CCGGCCAAGGGTGGGAGGGAGGGGGCCGG	60.00%
Apta_33	DNA	GCGGTAAACTGCGTCCGAAGGGGCTGCAGTGACCCGAATGGGTCCGCCGCGAAGCG	58.93%
Apta_218	RNA	AGCCGCGAGGGGAGGGAUAGGGUAGGGCGCGGCU	57.50%
Apta_585	DNA	GATCGAGGGCAGCGATAGCTGGGCTAATAAGGTTAGCCCCATCGGTC	55.32%
Apta_343	DNA	AACAGAGGGACAAACGGGGGAAGATTTGACGTCGACGAC	55.00%
Apta_1167	RNA	GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC	55.00%
Apta_1265	DNA	CACGCACACAACAGCCAATAATGTATAACGCTGTCCACTGTGTGGTGTCCCCCGCGTCG	54.24%
Apta_643	DNA	ACCGATCCATCGAGTTTCTGAGAAAGGCCCGGAGAAACCGCGAGA	53.33%
Apta_815	DNA	CATCCGTCACACCTGCTCTGGCCACTAACATGGGGACCAGGTGGTGTTGGCTCCCGTATC	53.33%
Apta_71	DNA	GGCGAGTAGGTTGGTGTGGTTGGGGCTCGCC	52.50%
Apta_227	DNA	ACGCGCCTATGGTGCATCGCATGCCGACC	52.50%
Apta_245	DNA	ACAGGGGTGTGGGGACAGGGGTGTGGGG	52.50%
Apta_420	DNA	AGGGACGGGCTAAGTAACTGTGGAGGGT	52.50%
Apta_701	DNA	GTACTGGCGTTCGGGGGGTACCGCTGC	52.50%
Apta_1188	DNA	CGGGCGGGGCGTGGGGTGTTGGAGTGGAGGGCGGGGCGGC	52.50%
Apta_1194	DNA	GGGAGAGGTGGGAGCGGGGCCAGGG	52.50%
Apta_1068	DNA	CGGGACAAGACAACGAACGAACAGGAAGAGAACCGGAATGCAGACGTCAGGG	51.92%
Apta_1213	DNA	GGACTTGAAGAAAAGGGCGACACGCGAAGTCGATGTCGCGTCTGCCTGAAGTCA	51.85%
Apta_888	DNA	GGCGACCCCCGGGCTACCAGACAATGTACGCAGCAAGAGTGACGGTCGTACCTCGGAGTC	51.67%

ABOUT