Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 968
Aptamer sequence: AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG
Target unique ID: Other-15
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_882 | Dapt1 | Other | DN-toxin B | 60 nM | 20 mM Tris-HCl, 100 mM NaCl, 5 mM KCl and 10 mM MgCl2, 1 mM DTT, 0.05% Tween-20, pH 7.5 | 32155319 |
Structure information of aptamer
| Aptamer Sequence: | AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG |
| The optimal secondary structure in dot-bracket notation: | ...(((((((((((.(((.....))).))....)))))))))........ |
| The centroid secondary structure in dot-bracket notation: | ...(((((((.....(((.....))).........)))))))........ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_882 | Description | Dapt1 |
| Aptamer chemistry | DNA | Length | 50 nt |
| GC content | 48.0% | Molecular weight | 15,530.93 Da |
| Molarity of 1 μg/μl solution | 64.39 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Targeted binding |
| Sequence | AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG | ||
| Applications | Binding to degraded protein | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-15 | Name | DN-toxin B |
Activity data
 |
Interaction ID | 968 |
| Target type | Other | |
| Target unique ID | Other-15 | |
| Activity | 60 nM | |
| Binding Conditions/Buffer | 20 mM Tris-HCl, 100 mM NaCl, 5 mM KCl and 10 mM MgCl2, 1 mM DTT, 0.05% Tween-20, pH 7.5 |
|
| Assay | Binding curves of Dapt1 to FN-toxin B pre-exposed in unformed human stool for 1, 5 and 10 days. N.D. = Not detected |
|
| PubMed ID | 32155319 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_913 | DNA | GGCACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTT | |
| Apta_1230 | DNA | GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG | |
| Apta_42 | DNA | GCTGGTCTCTGCGGGTTGTTGCGCCGCGGCACCCTTGGCA | |
| Apta_146 | DNA | GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCG | |
| Apta_482 | DNA | AGCAAGGTTTGGTGTTGGTTGGTTGCTGGTTTTGGTTTC | |
| Apta_691 | DNA | CGACGCGCGTTGGTGGTGGATGGTGTGTTACACGTGTTGT | |
| Apta_692 | DNA | ACGTTGACGCTGGTGCCCGCTTGTGGTGCGAGTGTTGTGT | |
| Apta_750 | DNA | ATGCGAACAGGTGGGTGGGTTGGGTGGATTGTTCGGCTTCTTGAT | |
| Apta_858 | DNA | GGCTTCAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACG | |
| Apta_861 | DNA | CAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACGCAACCTG | |
| Apta_987 | DNA | GTACTGTCAATTGGAAGTGGTGTTACGTTGTGTAGTCAAATCAGTGC | |
| Apta_1091 | DNA | CCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG | |
| Apta_1237 | DNA | GGGGTTGTGTGGGGAGTTTGTCCTGTTGTG | |
| Apta_1262 | DNA | ACAAGGGGTGCAGGGGTCCGCGATTGTGACTGTGTGTGCG | |
| Apta_223 | DNA | CATTGAGATAGCTAGTTGTAGCTGCGTCATAGGCTGGGTTGGGTCTAGTGGTTGGGTGTG | |
| Apta_1280 | DNA | TCATATCCTTCTTGGTATCATTGCGTCATTTAGTCATTCATGTTATTCCCGAGGG | |
| Apta_149 | DNA | CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGATGGCGTGG | |
| Apta_284 | DNA | CACTCCGTCACTTTAGTGGATCTTTATAAAACCGATGCTG | |
| Apta_498 | DNA | GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTT | |
| Apta_693 | DNA | CGAGTTGAGCCGGGCGCGGTACGGGTACTGGTATGTGTGG |
DEV TOOL
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