AptaDB: Result

Interaction ID: 1271

Aptamer sequence: GGCACGATGTGGCTACATCGATCGCGGTACTGGTG

Target unique ID: 27294

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1204	Aptamer 6	Cell	Mycobacterium tuberculosis subsp. Tuberculosis	103 nM	20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl	28689112

Aptamer Sequence:	GGCACGATGTGGCTACATCGATCGCGGTACTGGTG
The optimal secondary structure in dot-bracket notation:	.((.((((((....))))))...))..........
The centroid secondary structure in dot-bracket notation:	.((.((((((....))))))...))..........

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1204	Description	Aptamer 6
Aptamer chemistry	DNA	Length	35 nt
GC content	60.0%	Molecular weight	10,843.95 Da
Molarity of 1 μg/μl solution	92.22 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	GGCACGATGTGGCTACATCGATCGCGGTACTGGTG
Applications	Detection of H37Rv in clinical diagnosis

Type	Detail	Type	Detail
ATCC ID	27294	Cell name	Mycobacterium tuberculosis subsp. Tuberculosis
Category	Bacteria	Organism	N/A
Product type	N/A	Cell type	N/A
Morphology	N/A	Tissue	N/A
Disease	N/A	Product format	Frozen
Antigen expression	N/A	Genes expressed	N/A
Cell description	This strain has been assigned to Risk Group 3-agents associated with serious or lethal human disease for which preventive or therapeutic interventions may be available.
Application(s)	N/A

No relevant experimental diagram	Interaction ID	1266
	Target type	Cell
	Target unique ID	27294
	Activity	103 nM
	Binding Conditions/Buffer	20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl
	Assay	N/A
	PubMed ID	28689112
No relevant experimental diagram	Interaction ID	1271
	Target type	Cell
	Target unique ID	27294
	Activity	103 nM
	Binding Conditions/Buffer	20 mmol/L HEPES buffer at pH 7.35, 1 mmol/L MgCl2, 120 mmol/L NaCl, 1 mmol/L CaCl2, and 5 mmol/L KCl
	Assay	N/A
	PubMed ID	28689112

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_1204	DNA	GGCACGATGTGGCTACATCGATCGCGGTACTGGTG	100.00%
Apta_1254	DNA	GGCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	62.50%
Apta_443	DNA	GGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	60.00%
Apta_541	DNA	CACGTGTTGTCTCTCTGTGTCTCGTG	60.00%
Apta_542	DNA	GCACGTGTTGTCTCTCTGTGTCTCGTGC	60.00%
Apta_543	DNA	GGCACGTGTTGTCTCTCTGTGTCTCGTGCC	60.00%
Apta_630	DNA	GACCAGGGCAAACGGTAGGGAGTGGTC	60.00%
Apta_1138	DNA	GCAGTGTGGGCGAATCTATGCGTACCGTTCGATATCGTG	58.97%
Apta_57	DNA	GCGGGTCGGTTGCTCGCTTCGCCCGATCGGTCTAAGGGTG	57.50%
Apta_438	DNA	AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	57.50%
Apta_438	DNA	AGCCATGACGATGTCGTTACGTAGATGCAGAGACTCCTAA	57.50%
Apta_444	DNA	AGCCATTACGATGTCGTTACGTAGATGCAGAGACTCCTAA	57.50%
Apta_913	DNA	GGCACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTT	57.50%
Apta_959	DNA	GGACCGCTAGGTTCGTGGCTGAGATCACGCGATATCAGTA	57.50%
Apta_1259	DNA	GGCGCGGCATGGTGTGGACTCCAGGCGGTAGGGATGTCGT	57.50%
Apta_320	DNA	GCACTCTGTGGGGGTGGACGGGCCGGGT	57.14%
Apta_674	DNA	GCACGATGGGGAAAGGGTCCCCCTGGGTTG	57.14%
Apta_937	DNA	TTGCCCACAGATCTGTGGAAGCCGAACCGCGTGCTAGTCGTG	57.14%
Apta_939	DNA	TTGCCCACCGTACTGTGCAGGTCGAACTACAGGCACGTCGTG	57.14%
Apta_1200	DNA	GGCACACAGGACTATACAGTGTTGCAGTGTTGCTG	57.14%

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