Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 939
Aptamer sequence: TGACCGAGTGTCTGGTCATTTTCGATGTCTGTTGTTAGGC
Target unique ID: Other-2
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_853 | SMV-26 | Other | Human Norovirus | 281 nM | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature | 25192421 |
Structure information of aptamer
| Aptamer Sequence: | TGACCGAGTGTCTGGTCATTTTCGATGTCTGTTGTTAGGC |
| The optimal secondary structure in dot-bracket notation: | ((((((......))))))........(((((....))))) |
| The centroid secondary structure in dot-bracket notation: | ((((((......))))))........(((((....))))) |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_853 | Description | SMV-26 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 47.5% | Molecular weight | 12,345.91 Da |
| Molarity of 1 μg/μl solution | 81.00 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | TGACCGAGTGTCTGGTCATTTTCGATGTCTGTTGTTAGGC | ||
| Applications | HuNoV capture and detection assays | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-2 | Name | Human Norovirus |
Activity data
 |
Interaction ID | 939 |
| Target type | Other | |
| Target unique ID | Other-2 | |
| Activity | 281 nM | |
| Binding Conditions/Buffer | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature |
|
| Assay | Equilibrium dissociation curves for select aptamers |
|
| PubMed ID | 25192421 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_1244 | DNA | GGAGATGTCAGTTGTGTGTGTGGTTATGGC | |
| Apta_1177 | DNA | TCCTACTCGTGATATCGGTGTTTATGGTGTCTGTCTTCATGTAGGA | |
| Apta_1155 | DNA | TAGTTTTATTTGTTCATTTTGTGTATTGTTTTGA | |
| Apta_1236 | DNA | GGACTGTTGTGGTATTATTTTTGGTTGTGC | |
| Apta_1240 | DNA | GGAGTAGTGGGGATTGTGGTGTATGTTGTC | |
| Apta_1243 | DNA | GGTGTTGTTGTTGGCTAGTTTGTTGTGGGC | |
| Apta_972 | DNA | TGACAGTACGTACTGAACTAATTTATAAGTAATTTGCTATGGTGGTATCC | |
| Apta_58 | DNA | GCACCTTGATGACATGATAGTCGTTGTGTATGCAGTTGGC | |
| Apta_165 | DNA | TGGACGAACTGCCCTCAGCTACTTTCATGTTGCTGACGCA | |
| Apta_263 | DNA | AGAGGGGAGGGTCGGGTATCGGCGTGTTCGGGGGATCTGC | |
| Apta_542 | DNA | GCACGTGTTGTCTCTCTGTGTCTCGTGC | |
| Apta_543 | DNA | GGCACGTGTTGTCTCTCTGTGTCTCGTGCC | |
| Apta_817 | DNA | TGCGTGAGCGGTAGGCCCCTACGACCCACTGTGGTTGGGC | |
| Apta_1036 | DNA | ATACCAGTCTATTCAATTGGGCCCGTCCGTATGGTGGG | |
| Apta_1176 | DNA | AGTATGATATCGGTGTTTATGGTGTCTGTCTTCATACT | |
| Apta_1210 | DNA | GGGGAGGCAGTGTGTTGTGTCGTGTGTGTGCTTGG | |
| Apta_1237 | DNA | GGGGTTGTGTGGGGAGTTTGTCCTGTTGTG | |
| Apta_1238 | DNA | GGTTTTGTGTTTGTGTTTTGTGGTTGTTGT | |
| Apta_1241 | DNA | GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_1242 | DNA | GGAGCGATTAGTAGTGGTCTTGTCTTTTGC |
DEV TOOL
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