Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1200
Aptamer sequence: UAGUGUGAGAGCCGUGAGUGAAAGGCCGCGACAAAGAUCGGA
Target unique ID: C7EXM1
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_1140 | I-2 | Protein | C7EXM1_SALTM | 20.27 nM | 30 mM Tris-HCl, pH 7.5, 150 mM NaCl, 1.5 mM MgCl2, 2 mM dithiothreitol, and 1% BSA | 23676911 |
Structure information of aptamer
| Aptamer Sequence: | UAGUGUGAGAGCCGUGAGUGAAAGGCCGCGACAAAGAUCGGA |
| The optimal secondary structure in dot-bracket notation: | ............((((.((.....))))))............ |
| The centroid secondary structure in dot-bracket notation: | ..........(((..........)))................ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_1140 | Description | I-2 |
| Aptamer chemistry | RNA | Length | 42 nt |
| GC content | 54.8% | Molecular weight | 13,714.27 Da |
| Molarity of 1 μg/μl solution | 72.92 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | UAGUGUGAGAGCCGUGAGUGAAAGGCCGCGACAAAGAUCGGA | ||
| Applications | Disease Diagnosis | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Uniprot ID | C7EXM1 | Protein name | Membrane protein (OmpC) (Outer membrane porin protein C) (Outer membrane protein C) (Outer membrane protein C protein-like protein) (Phosphoporin PhoE) (Porin) (Porin OmpC) |
| Gene name(s) | ompC | Organism | Membrane protein (OmpC) (Outer membrane porin protein C) (Outer membrane protein C) (Outer membrane protein C protein-like protein) (Phosphoporin PhoE) (Porin) (Porin OmpC) |
| Status | unreviewed in uniprot database | Length | 378 |
| Mass | 41,239 | Activity regulation | N/A |
| Involvement in disease | N/A | Catalytic activity | N/A |
| PDB ID(s) | N/A |
 |
Function | N/A |
Activity data
 |
Interaction ID | 1200 |
| Target type | Protein | |
| Target unique ID | C7EXM1 | |
| Activity | 20.27 nM | |
| Binding Conditions/Buffer | 30 mM Tris-HCl, pH 7.5, 150 mM NaCl, 1.5 mM MgCl2, 2 mM dithiothreitol, and 1% BSA |
|
| Assay | Determination of the dissociation constant (Kd) for the aptamer to the OmpC protein |
|
| PubMed ID | 23676911 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_135 | RNA | GGGAGGACGAUGCGGAUUCUGGUUACUGGCCGCCCCAGACGACUCGCCCGA | |
| Apta_714 | RNA | GGCGGUUCCUGCCGAAAGGCUCGUGGCAACGUC | |
| Apta_133 | RNA | GGGAGGACGAUGCGGUGAGUCGUUCCCUUCGUCCCCAGACGACUCGCCCGA | |
| Apta_134 | RNA | GGGAGGACGAUGCGGGCCGUUGUUGUGUGCCGCCCCAGACGACUCGCCCGA | |
| Apta_315 | RNA | GGGAGGACGAUGCGGUCGUAUUAUCCGCUGCACGCCAGACGACUCGCCCGA | |
| Apta_713 | RNA | GGCGGUGCUGGCCGAAAGGCGCUUGGAAACGUC | |
| Apta_855 | RNA | UCACUGUUAUCCGAUAGCAGCGCGGGAUGA | |
| Apta_131 | RNA | GGGAGGACGAUGCGGUCCUGUCGUCUGUUCGUCCCCAGACGACUCGCCCGA | |
| Apta_424 | RNA | UGCUAGUAUAUCGCACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCG | |
| Apta_27 | DNA | AGGGGGAGGGGTGGGGCCGGGCAGA | |
| Apta_85 | RNA | UGCGACUGUUAUAACCUAACAGCGACGUAAAGAUA | |
| Apta_91 | RNA | GAUAACCUCGAUGCGACGUUCGGCCUCAAAAUCAA | |
| Apta_96 | RNA | UCGCUAAUUAUAGGCGGAGUGCGACGUUAUAAAUA | |
| Apta_269 | RNA | AACGCUCAACGUCAGAAGGCAACGUAUAGGCAAGCACACUUCGACAUGAGGC | |
| Apta_599 | RNA | GUCUCUGUGUGCGCCAGAGAACACUGGGGCAGAUAUGGGCCAGCACAGAAUGAGGCCC | |
| Apta_711 | RNA | GGCGAUACCAGCCGAAAGGCCCUUGGCAGCGUC | |
| Apta_715 | RNA | GGCGCUGCACGCCGAAAGGCCCGUUGAAACGUC | |
| Apta_717 | RNA | GGCGCAGCCCGCCGAAAGGCACGUGGAACCGUC | |
| Apta_967 | DNA | GGGTAGCAGCCCCGCGGAGGGTCGGCTATAAGAACCAAGA | |
| Apta_599 | RNA | GUCUCUGUGUGCGCCAGAGAACACUGGGGCAGAUAUGGGCCAGCACAGAAUGAGGCCC |
DEV TOOL
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