Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 937
Aptamer sequence: CCATGTTTTGTAGGTGTAATAGGTCATGTTAGGGTTTCTG
Target unique ID: Other-2
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_851 | SMV-21 | Other | Human Norovirus | 101 nM | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature | 25192421 |
Structure information of aptamer
| Aptamer Sequence: | CCATGTTTTGTAGGTGTAATAGGTCATGTTAGGGTTTCTG |
| The optimal secondary structure in dot-bracket notation: | .((((.(((((.......))))).))))............ |
| The centroid secondary structure in dot-bracket notation: | .((((.(((((.......))))).))))............ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_851 | Description | SMV-21 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 40.0% | Molecular weight | 12,408.97 Da |
| Molarity of 1 μg/μl solution | 80.59 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | CCATGTTTTGTAGGTGTAATAGGTCATGTTAGGGTTTCTG | ||
| Applications | HuNoV capture and detection assays | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-2 | Name | Human Norovirus |
Activity data
 |
Interaction ID | 937 |
| Target type | Other | |
| Target unique ID | Other-2 | |
| Activity | 101 nM | |
| Binding Conditions/Buffer | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature |
|
| Assay | Equilibrium dissociation curves for select aptamers |
|
| PubMed ID | 25192421 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_590 | DNA | ACCATCTGTGTAAGGGGTAAGGGGTGGGGGTGGGTACGTCT | |
| Apta_850 | DNA | CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA | |
| Apta_1091 | DNA | CCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG | |
| Apta_1092 | DNA | CCCATGGTAGGTATTGCTTGGTAGGGATAGTGGGCTTGATG | |
| Apta_62 | DNA | AGTCCGTGGTAGGGCAGGTTGGGGTGACT | |
| Apta_223 | DNA | CATTGAGATAGCTAGTTGTAGCTGCGTCATAGGCTGGGTTGGGTCTAGTGGTTGGGTGTG | |
| Apta_675 | DNA | ACTGTCCGTCGGGTTTAGGGTGGCGTTCGG | |
| Apta_1149 | DNA | ATCATGGTGGGTATCGGCACTCGTTGGTTGAT | |
| Apta_1155 | DNA | TAGTTTTATTTGTTCATTTTGTGTATTGTTTTGA | |
| Apta_1241 | DNA | GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_1245 | DNA | AGTGTGAAGTGGTGTGTGTTGTTGTTTGTC | |
| Apta_861 | DNA | CAGGTTGGTCTGGTTGGGTTTGGCTCCTGTGTACGCAACCTG | |
| Apta_651 | DNA | CCTGCACCTCGTCCAGCATGCACACCGATGGCGGTCCTGTTTAGGGGGTGTGCGTG | |
| Apta_749 | DNA | GATCGGTGGGTGGGGGGGTTGGAGATCATCCTCAGGGATTACGTC | |
| Apta_1154 | DNA | TTAATTTTTTGATCTTTGATTGTTTTATTTTTTTTATTGTTTGTG | |
| Apta_1230 | DNA | GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG | |
| Apta_1280 | DNA | TCATATCCTTCTTGGTATCATTGCGTCATTTAGTCATTCATGTTATTCCCGAGGG | |
| Apta_65 | DNA | CTACCGTGGTAGGGAAGGTTGGAGTGTAG | |
| Apta_72 | DNA | AGTCAGTAGGTTGGTGTGGTTGGGGCTGACT | |
| Apta_75 | DNA | CACTGGTAGGTTGGTGTGGTTGGGGCCAGTG |
DEV TOOL
 |
 |
 |
 |